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NanoInside Theme Plan ‘Organs-on-Chips’

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Organs-on-Chips Technology Platform

The ‘Organs-on-Chips Technology Platform’ is one of the projects that is sponsored in the context of the NanoNextNL NanoInside program; it is related to the emerging theme of ‘Organs-on-Chips’.

Goal

The goal of the project is to lay the foundation for the development of joint and exchangeable standard technological solutions for organs-on-chips. This will lead to technical standardization of technology platforms and more streamlined development of new organ-on-chip systems.

Objectives

We will work towards our aim of technology standardization by a bottom-up approach, in which hands-on researchers (students, PhD candidates, post-docs) define and carry out their own collaborative pilot projects to find standardized solutions to challenges that they face.

Concretely, our proposed project will consist of four objectives:

·

Organizing two workshops and three lab visits

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Designing and carrying out joint pilot projects

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Setting up a digital forum for information exchange

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Visiting a relevant conference in technology development

Timeline and Planning

The approximate timeline of the project is as follows.

·

Workshop Meet and Greet. University of Twente; September 15, 2016

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Lab visits:

o

University of Twente; September 15, 2016

o

TU Eindhoven; September 23, 2016 (date not final yet)

o

TU Delft; September 30, 2016 (date not final yet)

·

Pilot projects

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Proposal application deadline: October 7, 2016 (date not final yet)

o

Proposal evaluation deadline: October 14, 2016 (date not final yet)

o

Pilot project execution: October 17 – December 9, 2016 (dates not final yet)

o

Pilot project report deadline: December 16, 2016 (date not final yet)

·

Workshop Tell and Sell. December 16, 2016 (date not final yet)

First Workshop and Lab Visit

The first workshop in the project will take place on September 15, 2016 at the University of Twente. The aim of the workshop is to stimulate hands-on researchers in organ-on-chip projects to generate concrete ideas for pilot projects with each other and/or relevant private partners.

Hands-on researchers – post-docs, Ph.D. students, Master students – in the field of organs-on-chips will be invited to the workshop and will be given the opportunity to present their work, as well as introduce concrete technical challenges they are facing. Representatives from industry (e.g. companies in the OOC-Manufacturing Cluster and others) will also be invited to introduce their relevant technical solutions and to facilitate the use of their technology in pilot projects.

The first lab visit in the project will take place on September 15, 2016 at the University of Twente. This will give the hands-on researchers the opportunity to get a feel for general facilities and specific set-ups that are used in the context of organ-on-chip research. This should help to facilitate the drafting of concrete pilot project proposals.

Specific programs for both the Meet and Greet workshop of September 15 and the lab visit of September 15 will appear on this website.

Partners

The ‘Organs-on-Chips Technology Platform’ project was initiated by researchers from University of Twente (UT), TU Delft and TU Eindhoven, which are three technical partners in the virtual institute of Human Organ and Disease Model Technologies (hDMT). The project applicants were Andries van der Meer (UT), Lina Sarro (TU Delft), Jaap den Toonder (TU/e), Janny van den Eijnden (hDMT), and Mieke Schutte (hDMT). The leaders of the NanoInside theme ‘Organs-on-Chips’ are Albert van den Berg (UT) and Vinod Subramaniam (VU). The project coordinator is Andries van der Meer (UT).

Contact

For questions regarding the project in general or the first workshop and lab visit in particular, feel free to contact Andries van der Meer.

NanoInside

NanoInside is a targeted program by NanoNextNL that aims to stimulate brief explorative projects related to promising emerging themes in the fields of nanotechnology and microtechnology. The program specifically supports activities that aim to more sharply define the emerging themes in terms of scope, stakeholders and future impact. The projects in the NanoInside program will run between June 2016 and December 2016.