Organs-on-chips are realistic laboratory models of human tissues and organs, based on the culture of human cell material in microfluidic devices. Nanosensors and microactuators are integrated in the devices and generate a dynamic and realistic cell culture microenvironment. As a result of this technical-biological integration, organs-on-chips exhibit specific functions that are similar to those found in human organs.
At the MIRA Institute, we develop organs-on-chips to investigate the safety of health products and to understand the mechanisms of disease. We hope that in the future organs-on-chips will find widespread use in biomedical science and will progressively replace animal models as the mainstay in efficacy and toxicity testing.