At the 7th World Congress of Biomechanics, a team of researchers from Aalborg University, Radboudumc, Materialise (Leuven, Belgium) and a research group from Prof. Bart Koopman (from the department of Biomedical Engineering at the Twente University) has been awarded the first prize in the Grand Challenge competition. This competition is a worldwide endeavour in which researchers are challenged to predict loads in the knee joint of a patient who has received a total knee replacement.