Mireille Claessens received togehter with Dr Otterman (Eindhoven University) a NWO Klein Grant
Manipulating the protein aggregation energy landscape: how a passive chaperone protein safeguards against disease.
Can Parkinson’s disease be prevented by improved quality control in cells? People are living longer, which increases the risk of quality control errors occurring in their cells. Quality control errors lead to diseases such as Parkinson’s. In this project, we will explore the potential of using small molecules to engineer an important part of the cellular quality control system. We will attempt to identify a mechanism that we can use to improve this quality control system, and thus prevent people from developing Parkinson’s disease.
16 April 2020