Publication: Bio macromolecules Exploring Intra- and Inter-Regional Interactions in the IDP α-Synuclein Using smFRET and MD Simulations

In the article G. Heesink et al,  shows that Coarse-grained molecular dynamics (CG-MD) simulation moddeling can be used for key interactions of trinsically disordered proteins α-synuclein. Single molecule FRET experiments show a good agreement with the modelled results.

The work can be read here: https://pubs.acs.org/doi/10.1021/acs.biomac.3c00404