2026 - 2032 PainCart2.0This project aims to advance Sensing & Actuation technologies to accelerate the development of safer, more affordable pain medications. Current drugs like opioids often cause severe side effects, such as respiratory depression. Evaluating both efficacy and side effects typically occurs late in clinical trials, once patients are involved. Our consortium seeks to enable this assessment already during phase 1 trials with healthy subjects. By enhancing the PainCart test battery, we will improve measurement quality and simulate patient-like pain sensitivity and side-effect susceptibility. This includes improved observation of central pain processing and temporary modulation of pain and respiratory responses, opening new avenues for drug development and pain research.

2025 - 2029 Ankle ReLoadThe EU-funded Interreg project Ankle ReLoad aims to support rehabilitation of ankle fracture patients by estimating the joint loading during daily using a small set of wearable sensors. It has been shown that early partial weight bearing of the affected joint supports faster rehabilitation, however, current practice does not support patients on how much their actual loading is. This application will provide that insight and helps clinicians to better understand the rehabilitation process.

2023 - 2027 Fit to purpose projectSport contributes to a healthy individual, collective happiness, and a productive society.
Unfortunately, (elite) sport has the downside that incorrect or excessive strain can lead to serious injuries. The financial impact of injuries, especially in elite sports, is enormous, running into millions annually.

2023 - 2027 The Vibrating Socks projectThe EU-funded Interreg VI project "Parkinson Vibrating Socks" aims to improve the mobility of people suffering from Parkinson's disease. Parkinson's disease is an incurable neurodegenerative condition that primarily occurs in individuals over the age of 60. Currently, about 182 out of 100,000 people are affected by Parkinson's. One of the most limiting symptoms is the phenomenon known as "Freezing of Gait," in which approximately 60% of all people with Parkinson's experience during the course of their illness. Freezing is described as if the feet suddenly stick to the ground, preventing the initiation of the next step, often leading to falls. Consequently, those affected often restrict their daily activities, which in turn reduces their quality of life.

2023 - 2027 RECENTRE: Risk-based lifEstyle Change: daily lifE moNiToring and REcommendationsIn 2030, there will be one million people in the Netherlands who have (had) cancer, and more than half of the Dutch population is overweight or obese. Both groups are at risk for severe late effects such as cardiovascular disease and decreased bone health. These risks are influenced by lifestyle factors, which can be changed using targeted interventions. Using smart holistic monitoring in daily-life and adaptive interventions developed with patients and citizens, the RECENTRE project aims to move care from primary/secondary care and come to a lower risk and disease burden of late effects, resulting in a higher quality of life and lower healthcare costs.

2022 - 2030 LoaD project: What is “healthy loading” for patients with osteoarthritis?Osteoarthritis is a painful, disabling joint disease that affects millions of people. There is no cure for Osteoarthritis.Patients are encouraged to stay physically active, but the optimal joint loading for the individual patient is not known. In the LoaD project, researchers from Medical Centers, Technical Universities, Colleges of Applied Science and companies collaborate to investigate what activity is optimal for an individual patient with knee osteoarthritis and how to coach patients towards healthy loading. With the obtained knowledge we will develop personalised support strategies for use in daily life.

2022 - 2026 X-double-dot projectThe x-double-dot project is a collaboration between Movella, a world leader in the field of inertial sensor technology, and the Biomedical Signals and Systems (BSS) group of the University of Twente. The aim of the project is to combine the knowledge of Movella and the BSS group to create new ideas with regard to personalized analysis of 3D human movement analysis using a sparse configuration of inertial sensors, specifically in application areas such as sports and rehabilitation.

2021 - ongoing Remote monitoring after colon surgery: towards colon surgery in day care in the MST hospitalMore than 14,000 (partial) colon resections or colectomies are proceeded every year in the Netherlands, for example in case of colon cancer. Resection of this organ has a huge impact on the human body which needs physiological adaptations and a long recovery. The goal of this research is reducing hospital stay after colon surgery to daycare in the MST hospital by selecting patients at low risk of complications and using remote monitoring.

2020 - 2027 INTENSE Project - Innovative Neurotechnology for societyThe rapid emerging scientific field of neurotechnology may radically change medical practice. This field connects important advances in our understanding of brain function to a recent surge in the technological possibilities to write to and read from the brain. INTENSE brings together academic researchers, medical doctors and companies and patient organizations with the aim to expand the possibilities of linking digital technology to the nervous system to profoundly improve the lives of patients with blindness, deafness, paralysis and epilepsy.

2017 - ongoing Optimal care for frail elderly with a hip fracture:decision support for surgeryHip fractures are a significant health care problem in the elderly, affecting 1.5 million people per year worldwide. Identification of patients at high risk for early mortality is beneficial, to inform the patient about the prognosis of hip fracture surgery and to customize care. Aim of this project is to use both data-driven and structured expert judgement approaches to come to clinical decision support for decisions on hip surgery for frail elderly.