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[M] Cell detection under defocus blur

BACHELOR Assignment

Cell detection under defocus blur

Type: Bachelor EE/CS/HMI 

Period: TBD

Student: (Unassigned)

If you are interested please contact :

Introduction:

As the demand of medical image analysis increases, the aid of deep leaning models has shown its great potential in improving diagnose speed, releasing medical experts from numerous workloads. However, a high-performance medical used model requires not only high accuracy, but also robustness.

For whole-slide cell images, one of the most common corruptions is defocus blur [1], because the focus of a microscope is inappropriately set, or the positions of cells are non-coplanar. In large-scale cell image analysis, the out-of-focus problem is inevitable and must be dealt with to ensure reliable predictions.

Objective:

The goal of this project is to detect cells in partial-blurry images (mainly due to defocus blur) and explore the efficiency of defocus blur detection  algorithms [2] in improving robustness towards such corruption.

References:

  1. https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-018-2087-4
  2. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205387