CARE-FLOW

CARE-FLOW is a four-year Interreg VI project led by the University of Twente to improve cross-border collaboration in healthcare delivery between the Netherlands and Germany. The goal is to develop intelligent, data-driven software solutions that streamline patient flows and optimize healthcare capacity in the region.

Why CARE-FLOW?

Healthcare systems in both countries are under increasing pressure due to:

This strain is especially visible in border regions, where a lack of coordination between systems leads to inefficiencies like duplicated resources, uneven workloads, and delays in care. While past crises, such as the COVID-19 pandemic, have shown the value of cross-border cooperation, current approaches remain fragmented and largely ad hoc.

Our Solution

CARE-FLOW harnesses the power of data analytics, mathematical modeling, Artificial Intelligence and Information Technology to:

The algorithms and software will be co-developed with input from healthcare providers to ensure it fits real-world needs and is easy to adopt. A dedicated training model will also support its practical integration.

Collaboration

The CARE-FLOW project brings together a diverse and cross-border consortium of universities, healthcare providers, and software companies from the Netherlands and Germany.

Who is leading the algorithm development in CARE-FLOW?

UT researchers from the Center for Healthcare Operations Improvement & Research (CHOIR), which includes Derya Demirtas, Daniela Guericke, Sebastian Rachuba, Anne Zander, Erwin Hans, and Richard Boucherie.

Partners

  • Universities
    • Universiteit Twente (Lead Partner)

      Leads the CARE-FLOW project, coordinating research, communication, and project management. Develops intelligent, data-driven tools for optimizing patient logistics and cross-border healthcare collaboration.

    • Universität Münster (Core Partner)

      Contributes academic expertise in crisis and healthcare management, supporting evaluation methods and project result analysis.

    • Universitätsklinikum Münster (Core Partner)

      Provides expertise in epidemiology and simulation. Leads forecasting activities and supports the integration of results into healthcare planning algorithms.

  • Software Companies
    • Stokhos B.V. (Core Partner)

      A key SME specializing in real-time deployment of emergency services. Leads software development for emergency services (WP7) and supports data collection/evaluation for WP3 and WP10. Closely collaborates with SafetyCT on geolocation based route optimization.

    • ORTEC B.V. (Core Partner)

      Contributes to software development for hospitals and VVT institutions. Leads WP3 (data management) and WP8 (software implementation). Their Rhythm team brings knowledge in capacity planning and healthcare analytics.

    • L2R GmbH (Core Partner)

      Leads WP10 (Trials and Training). Brings expertise in training and applying digital emergency response technologies, focusing on complex tool introduction across healthcare systems.

Associates

  • Associates

    Radboud universitair medisch centrum / Radboudumc • Universitair Medisch Centrum Groningen (UMCG) • Medisch Spectrum Twente • Klinikum Osnabrück GmbH • Ambulance Oost • Ziekenhuisgroep Twente • De Posten • Zorgschakel • Livio Holding B.V. • GGD Flevoland • Kreis Borken • Safetyct • Acute Zorg Euregio

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Work Packages

  • WP1 (Project Management)
    • University of twente

      Coordinates the overall project, monitors progress, reporting, and partner collaboration.

  • WP2 (PR and Communication)
    • University of Twente

      Manages communication activities, public visibility, stakeholder engagement, and compliance with Interreg/EU branding.

  • WP3 (Data Management)
    • ORTEC B.V.

      Identifies and prepares healthcare data, ensures GDPR compliance, and develops a central data platform.

  • WP4 (Forecasting and Modelling)
    • University Hospital of Münster UKM

      Develops predictive models for healthcare demand including peak/crisis scenarios using simulation and epidemiological data.

  • WP5 (Cross-Border Ambulance Deployment)
    • University of Twente

      Designs algorithms and digital strategies for ambulance repositioning across borders.

  • WP6 (Patient Flow & Capacity Management)
    • University of Twente

      Designs algorithms for smart patient flow steering and efficient use of hospital and aftercare capacity.

  • WP7 (Emergency Services Software)
    • Stokhos B.V.

      Enhances Stokhos' Seconds platform with forecasting and cross-border routing from WPs 4 and 5.

  • WP8 (Hospital and Aftercare Software)
    • ORTEC B.V.

      Integrates planning tools WPs 4 and 5 into ORTEC's Healthcare Suite for real-world hospital and care use.

  • WP9 (Evaluation)
    • University of Münster

      Evaluates tool effectiveness and user experience, supports project-wide reflection and improvement.

  • WP10 (Trials & Training)
    • L2R GmbH

      Organizes live trials and develops training materials to support healthcare staff in using the tools.


Funding & Support

The CARE-FLOW project is carried out as part of the Interreg VI-Program Deutschland-Nederland and has a total budget of 4.6 million euros. It is co-financed with €2,883,585.81 by the European Regional Development Fund (EFRE/EFRO), the Dutch Ministry of Economic Affairs and Climate Policy (EZK), the Ministry for Economic Affairs, Industry, Climate Protection and Energy of the State of North Rhine-Westphalia (MWIKE NRW), and the provinces of Flevoland, Groningen, and Overijssel.