Nanobiophysics Group uses two main laboratories, the physics laboratory hosts many modern tools to study cell interaction and protein aggregations. Many (custom-build) microscopes are available build for a broad and versatile applications. Laboratory ZH174 is restricted area due to the AP-I & LASER4 classification, it's allowed to study ML-1 bio-samples in a closed container.
Keywords: Nanopositioners, lasers, fluorescence, TIRFM total internal reflection microscopy, darkfield, AFM atomic force microscopy, confocal microscopy, fluorescent lifetime, spectroscopy, lightscatter. nanophotonics, LDOS, imaging,
Overview of microscopy techniques
Atomic Force microscopy.
1. Bruker Catalyst AFM for scanning, tapping and peak force imaging, compatible with live cells.
2. Multiple top-head design AFM systems, for versatile sample interaction/manipulation by AFM.
Fluorescence Microscopy Techniques
1. Single molecule sensitive confocal microscope, single TCSPC channel
2. PicoQuant, FCS compatible microscope, dual TCSPC channels
3. PicoQuant, Confocal microscope TCSPC extended with STED
4. Single molecule sensitive microscope, wide filed based for PALM, STORM dual channel widefield/TIRF
5. Commercial Nikon Ti-E TIRF microscope, Single molecule sensitive.
6. Fluoromax4 photo spectrometer with lifetime extension
7. Nikon TI-2000 fluorescent microscope with live cell incubator.
Custom build Dynamic Light Scatter setup (towards Static Light scatter)
Olympus GX71, transmission and reflection compatible darkfield inverted microscope for scattering nano-particles.