Bioinspired Molecular engineering

Welcome and thank you for visiting the Jonkheijm research group. Our lab is part of the cluster Organic and Materials Chemistry and Technology, the MESA+ Institute for Nanotechnology and the TechMed Centre of the University of Twente in Enschede, the Netherlands.

Our team of BSc, MSc, PhD students and postdoctoral research associates are exposed to many diverse research tools such as synthetic chemistry, material science, molecular biology, live-cell high-resolution microscopy, biochemistry and cell biology tools. 

Often, preparative procedures to render materials with bioactive, mechanosensitive and spatiotemporal modules rely on trial-and-error and serendipity. Can dynamic/spatiotemporal presentation of bioactive ligands on implanted biomaterials be exploited for modulating in-vivo cell behaviour and to elicit cascades of reparative responses? Because dynamic attachment in-vivo is intricately related to cell function, it comes as no surprise that thorough understanding of forces and dynamics of the building blocks and correlating these with cell responses using state-of-the-art microscopy and analytics is at the very forefront of present-day research and will bring about a paradigm shift for developing next-generation biomaterials. Please use the links above to learn more about our research group. 

We collaborate on these topics with different groups located at the University of Twente, University of Eindhoven, ETH Zurich, University of Munster, University of Utrecht, University of Maastricht, IMN Saarbrucken, Limerick University, University of Parma, Tsinghua University Beijing, University of Toronto, University of Leeds. Collaborations and feedback are most welcome.