Vascular disease modeling in Organs-on-Chips
Our research is focused on understanding human vascular diseases and developing therapeutic strategies using advanced in vitro models, particularly ‘Organs-on-Chips’. We employ microfluidic technology to create 'Vessel-on-Chip' models, enabling us to simulate and study in vitro vascular dysfunction, including inflammation, immune cell-recruitment and thrombosis. This approach allows unique opportunities to model vascular diseases (both of the large vessels and the microvasculature), thereby providing powerful tools for the study of cardiovascular health and disease progression.
