Anton Nijholt started his professional life as a scientific programmer at TNO, Rijswijk, the Netherlands. He studied mathematics and computer science at Delft University of Technology and moved to live in Amsterdam and do his PhD in theoretical computer science at the Vrije Universiteit. He was employed at several universities in and outside the Netherlands before 'settling down' at the University of Twente in 1989 as a full professor where he initiated and led the Human Media Interaction research group until his retirement in 2011. During that period the group took part in many Dutch and European research projects on multimodal and multi-party interaction, information retrieval and brain-computer interfacing. Nijholt supervised the research of more than fifty PhD students.
Nijholt organized and co-organized many conferences, workshops, and special sessions as program chair or general chair (ACE, FG, IVA, ICMI, ACII, Intetain). A few years (2015-2017) he was global research fellow at the Imagineering Institute in Iskandar, Johor, Malaysia. Presently (2018) he is member of Microsoft's Technical Leadership Advisory Board on Brain-Computer Interfaces (BCI). He is also editor-in-chief of Frontiers in Human-Media Interaction and Springer Book Series Editor Gaming Media and Social Effects. Recent keynotes talks (2015-2018) have been delivered on brain-computer interfacing, humor, and playable cities.