MESA+ University of Twente
The BIOS Lab-on-a-chip group

Introduction: Microdevices for Chemical Analysis

The theme of Microdevices for Chemical Analysis aims at engineering novel devices to measure chemical quantities, pushing boundaries in applications to explore unknown territory. Often, this relates to faster, or better spatially resolved measurements at lower concentrations in small volumes. Micro- and nanofabrication techniques are used to enhance electrochemical, optical or mass spectrometric readout. The ultimate goal is to create new, yet robust tools for routine use in the lab or point-of-care applications. Collaborations include various research groups specialized in analytical chemistry, microfabrication companies, as well as various research groups oriented towards applications in neurology and (photo)catalysis.


Hybrid push-pull perfusion probes with high temporal and spatial resolution to study the onset of a migraine and to unravel processes in the brain (VENI grant, Spinoza and Herseninstituut collaboration)


Development of a droplet microreactor platform for ‘Single Catalyst Particle Diagnostics’ (MCEC gravity program)


Development of surface enhanced FTIR/SERS spectroscopic readout in a microchip’ (MCEC gravity program)


Biological probing using microdroplets and mass-spectrometry


Capacitive deionization on chip for small volume sample preparation


PFS (polyferrocenylsilane) based coulometric and electrochemical biosensors (collaboration with MTP group)


Development of Fluidic Circuit Boards and interconnects to bridge the gap from Lab to Fab (MFManufacturing EU project)


Novel route to fabrication of structured micro-particles, and tools to deepen our understanding of the Ouzo effect

For more information contact: Mathieu Odijk








+31 (0)53 489 4620




Carré 2.413








3D nanoprinted woodpiles made of PFS

Artist impression of capactive deionization on-chip