Research overview

The BIOS Lab on a Chip chair (“Miniaturized systems for biomedical and environmental applications”) aims at the research and development of Lab on a Chip (LOC) systems.

OUR MISSION 

Biomedical microdevices

The focus of this theme is on the development of microfluidic systems for (bio)-medical applications, thereby increasing the knowledge of biological systems and improving the diagnostics and treatment of diseases. Microfluidics are a perfect tool for this, since dimensions comparable to single cells are used, low sample volumes are needed and multiple functionalities can be integrated in one platform. 

P.I.: Prof.dr.ir. Loes Segerink

Nanopores on-chip for e-health applications

We develop biological nanopores for use as biosensors to detect health- and environmentally-relevant molecules. The aim is to integrate these sensors into electronic devices for application in clinics or at home. Additionally, we are exploring the repurposing of these pore-forming proteins for anti-cancer therapies.

P.I.: Dr. Carsten Wloka

Lab-on-a-chip tools for nanobiology

Nanotechnology has a lot to offer to modern biophysics and nanobiology. We bring the lab-on-a-chip technology to it's ultimate limits - manipulation of single protein molecules. We develop single molecule platforms based on dielectrophoresis and electrophoresis to study dynamic properties of protein molecules.

P.I.: Dr. Sergii Pud

Dynamics of Functional Soft Matter

Dynamics of Functional Soft Matter investigates functional soft-matter systems—microbubbles, lipid nanoparticles, and droplets—using microfluidics to create, control, and probe them. We study the physical and interfacial principles that govern their formation, behavior, and functionality, with the goal of advancing non-invasive biomedical imaging, sensing, and therapy.