The cartoon shows my research area. The S-curve representing the heat flux as a function of the superheat i.e. the temperature difference between the solid and the liquid captures the various regimes of heat transfer. Most of the studies are focused on the fundamentals of bubble formation and the subsequent fluid mechanics and heat transfer in the so-called nucleate regime i.e. when the object is already cold and the cooling by the fluid is to maintain the objects temperature, which we call steady state. My interest is to investigate the factors that play a role during the cooling of an object from a room temperature to a cryogenic temperature, namely the transient state. The complex transient cooling phenomena with various cryofluids at various thermodynamic states, namely saturated, sub-cooled, mixture and slush requires a systematic study. Understanding cooling is vital in several application areas where I am involved: ablation of tissues by fast freezing, cryopreservation, food freezing, food processing, cold transportation, aviation and vitrification.