Publications

2023

13. Krab-Hüsken, L. E.; Pei, L.; de Vries, P. G.; Lindhoud, S.; Paulusse, J. M. J.; Jonkheijm, P.; Wong, A. S. Y.* “Conceptual Modeling enables Systems Thinking in Sustainable Chemistry and Chemical Engineering” J. Chem. Educ. 2023, 100, 12, 4577–4584. https://doi.org/10.1021/acs.jchemed.3c00337.

This work appearedand in C2W Mens&Molecule as "Uitzoomen en vooruitkijken: conceptueel modelleren in de klas" and in UT News as "Scheikunde leren vergemakkelijken met conceptueel modeleren (NL)" and "Facilitating learning chemistry with conceptual modeling (EN)".

12. Koyuncu, A. H.; Movilli, J.; Sahin, S.; Kriukov, D. V.; Huskens, J.;* Wong, A. S. Y.* “Polylysine-coated surfaces drive competition in chemical reaction networks to enable molecular information processing” ChemSystemsChem 2023, 6, e20230003, 1-7. https://doi.org/10.1002/syst.202300030. 

This work appeared in C2W Mens&Molecule as "Evenwichtsverstorende coating (NL)" and "Equilibrium disrupting coating (EN)", and was selected as Cover Art in ChemSystemsChem (https://doi.org/10.1002/syst.202300052). 

The image shows a microfluidic channel with multilayer polylysine surfaces, which provide the potential to bestow an acid-base equilibrium with the capacity of signal transduction. Cover design by Niels van der Velde (University of Twente, NL)

11. ter Harmsel, M.; Maguire, O. R.; Runikhina, S. A.; Wong, A. S. Y.; Huck, W. T. S.*; Harutyunyan, S. R.* “A catalytically active small organic molecule oscillator” Nature 2023, 621, 87–93. https://doi.org/10.1038/s41586-023-06310-2 

2022

10. Kriukov, D. V.; Koyuncu, A. H.; Wong, A. S. Y.* "History dependence in a chemical reaction network enables dynamic switching" Small 2022, 18, 2107523, 1-7. https://doi.org/10.1002/smll.202107523

This work appeared in UT News as "Calculating with chemical reactions with a memory" (in Dutch "Rekenen met slimme chemie die kan onthouden"). 

2015-2020

9. Maguire, O. R.; Wong, A. S. Y.; Westerdiep, J. H.; Huck, W. T. S.* “Early Warning Signals in Chemical Reaction Networks” Chem. Commun. 2020, 56, 3725-3728 DOI: 10.1039/D0CC01010C

8. Maguire, O. R.; Wong, A. S. Y.; Baltussen, M. G.; van Duppen, P.; Pogodaev, A. A.; Huck, W. T. S.* “Dynamic Environments as a Tool to preserve Desired Output in a Chemical Reaction Network” Chem. Eur. J. 2020, 26, 1676-1682. DOI: 10.1002/chem.201904725

7. Cafferty, B. J.; Wong, A. S. Y.; Semenov, S. N.; Belding, L.; Gmuer, S.; Huck, W. T. S.; and Whitesides. G. M.* “Robustness, Entrainment, and Hybridization in Dissipative Molecular Networks, and the Origin of Life” J. Am. Chem. Soc. 2019, 141 (20), 8289-8295. DOI: 10.1021/jacs.9b02554

6. Pogodaev, A. A.; Wong, A. S. Y.; Huck, W. T. S.* “Photochemical Control over Oscillations in Chemical Reaction Networks” J. Am. Chem. Soc. 2017, 139, 15296-15299. DOI: 10.1021/jacs.7b08109

5. Wong, A. S. Y.*; Huck, W. T. S.* “Grip on Complexity in Chemical Reaction Networks” Beilstein J. Org. Chem.2017, 13, 1486–1497. DOI: 10.3762/bjoc.13.147

4. Postma, S. G. J.; te Brinke, D.; Vialshin, I. N.; Wong, A. S. Y.; Huck, W. T. S.* “A Trypsin-based Bistable Switch Tetrahedron”, Tetrahedron Lett. 2017, 73 (33), 4896–4900. DOI: 10.1016/j.tet.2017.04.053

3. Wong, A. S. Y.; Pogodaev, A. A.; Vialshin, I. N.; Helwig, B.; Huck, W. T. S.* “Molecular Engineering of Robustness and Resilience in Enzymatic Reaction Networks” J. Am. Chem. Soc. 2017, 139 (24), 8146 – 8151. DOI: 10.1021/jacs.7b00632 

2. Wong, A. S. Y.; Postma, S. G. J.; Vialshin, I. N.; Semenov, S. N.; Huck, W. T. S.* “The Influence of Molecular Structure on the Properties of Out-of-equilibrium Oscillating Enzymatic Reaction Networks” J. Am. Chem. Soc. 2015, 137, 12415−12420. DOI: 10.1021/jacs.5b08129

1. Semenov, S. N.^#; Wong, A. S. Y.^#; Van der Made, R. M.; Postma, S. G. J.; Groen, J.; Van Roekel, H. W. H.; De Greef, T. F. A.; Huck, W. T. S.* “Rational Design of Functional and Tunable Oscillating Enzymatic Networks” Nat. Chem. 2015, 7, 160-165. ^#Authors with equal contributions. DOI: 10.1038/nchem.2142

2. Fink, M. J.; Wong, A. S. Y.; Whitesides, G. M. "Sparse and non-sparse coding in molecular data storage" 2021, Patent No. WO 202 1/062220.

1. Wong, A. S. Y.; Fink, M. J.; Mohamed, K. A.; Whitesides, G. M. "Array-based molecular computation on reactive surfaces". 2021, Patent No. WO/2021/041667.