ISPOR Student Chapter

Educational Symposium


On Thursday, October 12th 2017, the ISPOR University of Twente Student Chapter organizes an educational symposium about how the methodologies that are being taught at the University for developing, evaluating, and implementing healthcare interventions, are being applied in practice. Although the symposium is primarily organized for the educational programs of Health Sciences, Technical Medicine, Biomedical Engineering, and Industrial Engineering and Management, registration is open to all University of Twente students and employees.

Point-of-care tests are a perfect example of healthcare interventions for which the development, evaluation, and implementation are all extremely relevant and challenging. Developing these test is a real technical challenge, as the devices should be easy and quick to use, but also accurate. As for any diagnostic device, evaluating point-of-care test is difficult, as effects are likely to occur only as a consequence of the treatment that is provided according to the diagnosis. These tests are mostly implemented at the general practitioners and appropriate implementation is crucial. Therefore, real-life examples of the development, evaluation, and implementation of point-of-care tests will be used throughout the symposium to address the corresponding methodologies.

The introduction to point-of-care tests and the development of healthcare interventions in general will be provided by prof. dr. Maarten IJzerman and prof. dr. Ron Kusters, who are both affiliated to the University of Twente. Subsequently, national and international speakers from industry, government, and academia will discuss different stages in the development of point-of-care tests. The symposium will end with an interactive discussion, followed by a reception with free drinks. More information about the speakers, as well as a detailed program, are provided below. 

Registration for this symposium is free but mandatory. Students of the applicable educational programs can register at the website of their Study Association (See: Sirius, Paradoks, or Stress). Others can register using this link. For any questions, please feel free to contact the ISPOR University of Twente Student Chapter at

DEVELOPMENT: Dr. Olaf Such, Head of Research and Development, Handheld Diagnostics, Philips BG Emerging Businesses, the Netherlands

Point of care diagnostics pose specific challenges within Product Development. This has to do with a number of requirements that implicitely or explicitly result out of user & customer needs, regulatory requirements and industrialization strategies. The talk will focus on these aspects and discuss the impact to the development process of POC Diagnostic Tests.

Olaf Such is the Head of Research and Development at Philips Handheld Diagnostics since 2016, where he leads the teams responsible for Innovation and Product Realization for this In-Vitro Diagnostics Venture within Philips. He carries a Ph.D. in  Biomedical Engineering and an MBA from RWTH Aachen, Germany.

Previously, he was Head of Strategy & Partnerships for Philips MRI, based in Best, the Netherlands, and was the Global Head of Clinical Science for Philips MRI. Before that, he lead innovation activities on Physiological Measurements and Life Support, bridging high and low care application settings between Hospital and Home, in the Philips Corporate Research organization in Eindhoven, the Netherlands, and Aachen, Germany, from 1998 to 2006.

He is active in IEEE EMBS as a senior member, former Vice President of the German Society of Biomedical Engineering (DGBMT im VDE) and member of the Advisory Board of the EE faculty of the Technical University Eindhoven. He was born in 1966 in Moscow, grew up in Australia, and is married with two children.

EVALUATION: Rebecca Albrow, Senior Technical Adviser, Diagnostics Assessment Programme, National Institute for Health and Care Excellence, United Kingdom

The NICE diagnostics assessment programme has been undertaking cost effectiveness analysis on diagnostic technologies since its inception in 2011. Acknowledging that diagnostic technologies often have lower levels of evidence than pharmaceuticals, modelling is central to our assessments which frequently use a ‘linked evidence’ approach to compensate for the absence of end to end studies. This presentation will provide an overview of how NICE assesses diagnostic technologies, with a particular emphasis on point of care technologies. Using real-world examples from past assessments it will outline how the value proposition of point of care technologies may differ from laboratory based tests, and how these differences are captured within our published reference case.

Rebecca is the Senior Technical Adviser in the NICE Diagnostics Assessment Programme. She has been in the team since 2013, previously working as a Technical Analyst and a Technical Adviser. She joined NICE in 2012, initially working in the Medical Technologies Evaluation Programme.

Rebecca has a Masters of Public Health from the University of Manchester. Prior to joining NICE she spent several years working on NHS NIHR funded research projects investigating the use of new technologies in cervical screening.

FROM RESULTS TO CONSEQUENCES: Prof. dr. Patrick Bossuyt, Professor of Clinical Epidemiology, University of Amsterdam, the Netherlands

Health care professionals rely on medical tests to support diagnostic judgment and clinical decision making: in vitro diagnostics, imaging, microbiology, pathology, function tests, and many more. Like all other interventions, these medical tests should be properly evaluated before they are introduced into clinical practice. Overall, the evaluation of medical tests is changing, from an exclusive attention on the valdiity of test results to a more global appraisal of the consequences of testing itself. Payers, regulators and other decision-makers increasingly emphasize that testing should help to improve health outcomes. This shift comes with several challenges. 

Patrick M. Bossuyt is the professor of Clinical Epidemiology at the Academic Medical Center of the University of Amsterdam, where he leads the Biomarker and Test Evaluation Research program. The BiTE Program aims to appraise and develop methods for evaluating medical tests and biomarkers, and to apply these methods in relevant clinical studies. In doing so, the program wants to strengthen the evidence-base for rational decision-making about the use of tests and testing strategies in health care. Bossuyt spearheaded the STARD initiative for the improved reporting of diagnostic test accuracy studies.

Dr Bossuyt has authored and co-authored several hundred publications in peer reviewed journals and serves on the editorial board of a number of these, including Radiology and Clinical Chemistry. He chairs the Scientific Advisory Committee of the Dutch Health Insurance Board, which oversees the health care benefits covered in the national insurance program.

CHAIR & DISCUSSION LEADER: Hesther Faber, Professional Coach

Hesther Faber is a social psychologist, symposium chair, and professional coach. She worked as a learning and development consultant for different (financial) service providers and governmental institutions from 2001 till 2013. She now works and lives in Friesland with her two kids.

Detailed program:

- Location: Spiegel 1, University of Twente, Enschede, the Netherlands






Registration + Coffee and Tea

13:00 - 13:30

Part I


- Welcome

- Symposium overview

Koen Degeling, President, ISPOR University of Twente Student Chapter

13:30 - 13:40

Presentation I

- Overview Development Cycle

- Introduction to point-of-care tests

Maarten IJzerman, Professor, University of Twente

Ron Kusters, Professor, University of Twente

13:40 - 14:15

Presentation II


Olaf Such, Head of Research and Development, Philips

14:15 - 15:00

Coffee Break

Coffee and Tea with Cake

15:00 - 15:15

Part II

Presentation III


Rebecca Albrow, Senior Technical Adviser,National Institute for Health and Care Excellence (UK)

15:15 - 16:00

Presentation IV

From Results to Consequences

Patrick Bossuyt, Professor of Clinical Epidemiology, University of Amsterdam

16:00 - 16:45


Roundtable discussion on point-of-care tests

All speakers

16:45 - 17:30


Free drinks

17:30 onwards