In addition to the optical and electron microscopy facilities with various imaging modes to investigate a sample in microspace (1 m = 10-6 m) and nanospace (1 nm = 10-9 m), MAC-Twente offers a variety of chemical analysis techniques to explore the surface and internal structure of a specimen. Most of the techniques are commonly used to study inorganic materials but some of these can be used on specimens of organic nature too. The chemical analysis techniques offered by MAC-Twente will, e.g., give the elemental composition and in some cases also the chemistry of shallow surfaces of the sample and its bulk. Knowledge of the chemical constitution of the surface is required in areas such as adhesion, catalysis, photonics and chemical modification. Analyses can be done on scales from nanometres to micrometres in the normal direction, and from nanometres to millimetres in the lateral direction. Concentrations can be determined down to 0.1 atomic % . The MAC-Twente analysis facilities are completed by technologies for characterisation of samples in liquid.