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OoCCT & BRAINS symposium

The Organ-on-Chip Centre Twente and Centre For Brain-Inspired Nano Systems join forces! On 3 September 2024 OoCCT & BRAINS will co-organise a symposium hosting Magnus Fontes, general manager of Roche, joined by two speakers from the University of Twente. 

SpeakerS

Magnus Fontes: "From single cells to complex systems"

During the last decades the developments in bio and digital technologies have led to a transformation of healthcare. We can now, with high throughput, at the single cell level, measure DNA and RNA and protein abundances, as well as collecting spatial information on the measured single cells. I will give examples of some of the latest biomedical insights derived from such data, with a focus on understanding the human immune system and its interactions with intrinsic or extrinsic perturbations, as well as highlight some of the connected modeling challenges that the community currently struggles with.

Short biography on Magnus Fontes:

Dr. Fontes is Adjunct Professor of Mathematics at Lund University and General Manager of Institut Roche in Paris, France. Institut Roche is Roche’s institute for collaborative and multidisciplinary biomedical research, see https://institut.roche.com/. Magnus Fontes’ research interests and publications cover fundamental mathematics as well as mathematical modeling applications, including development of mathematical modeling methods and algorithms targeting biomedical and clinical applications. His current research is directed towards modeling of pathogen-immune system interactions and systems immunology, trying to uncover new functional biological mechanisms. Magnus Fontes is a co-founder of the bioinformatics software company Qlucore.

Hanumantha Rao Vutukuri

Dr. Vutukuri (BET-NBP) is a tenured assistant professor and lead the Active Soft Matter Lab at the TNW Faculty, University of Twente. His lab's core expertise is developing simplified biomimetic models, such as artificial microswimmers and active lipid vesicles. They use these models to investigate systems far from equilibrium by exploring how to control materials by powering them from within, understanding how order can arise from disorder, by examining lipid membrane's response to highly localized forces and their mechanics, and by studying the transport of artificial microswimmers in complex fluids, all through the lens of soft matter science.

Janine Post

Dr. Post (BET-DBE) her research is aimed toward understanding the mechanisms regulating cartilage hypertrophy and degenerative cartilage diseases. For this she employ a variety of molecular biology, biochemical and biophysical techniques in combination with computational modeling to understand signaling pathways important in the development, maintenance and loss of cartilage homeostasis.


Programme

Location: tbd

  • 15:00 - 15:15 h: Hanumantha Rao Vutukuri
  • 15:15 - 15:30 h: Janine Post
  • 15:30 - 16:30 h: Magnus Fontes
  • 16:30 - 17:00 h: drinks and networking