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BIOS: Lab-on-a-chip group
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2024

Article

Ring-shaped colloidal patterns on saline water films (2024)Journal of colloid and interface science, 673, 788-796. Hack, M. A., van der Linden, M. N., Wijshoff, H., Snoeijer, J. H. & Segers, T.https://doi.org/10.1016/j.jcis.2024.06.015Standardizing designed and emergent quantitative features in microphysiological systems (2024)Nature Biomedical Engineering, 8, 941-962. Nahon, D., Moerkens, R., Aydogmus, H., Lendemeijer, B., Martínez-Silgado, A., Stein, J., Dostanić, M., Frimat, J.-P., Gontan, C., de Graaf, M. N. S., Hu, M., Kasi, D., Koch, L. S., Le, K., Lim, S., Middelkamp, H. H. T., Mooiweer, J., Montreux-Ragot, P., Niggl, E., … Mummery, C. L.https://doi.org/10.1038/s41551-024-01236-0Multimodal Mapping of Electrical and Mechanical Latency of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocyte Layers (2024)ACS nano. Zhang, X., Burattini, M., Duru, J., Chala, N., Wyssen, N., Cofino Fabres, C., Rivera Arbelaez, J. M., Passier, R., Poulikakos, D., Ferrari, A., Tringides, C., Vörös, J., Battista Luciani, G., Miragoli, M. & Zambelli, T.https://doi.org/10.1021/acsnano.4c03896High-Speed Optical Characterization of Protein-and-Nanoparticle–Stabilized Microbubbles for Ultrasound-Triggered Drug Release (2024)Ultrasound in medicine and biology, 50(8), 1099-1107. Nawijn, C. L., Segers, T., Lajoinie, G., Berg, S., Snipstad, S., Davies, C. d. L. & Versluis, M.https://doi.org/10.1016/j.ultrasmedbio.2024.03.011Micro-Engineered Heart Tissues On-Chip with Heterotypic Cell Composition Display Self-Organization and Improved Cardiac Function (2024)Advanced healthcare materials, 13(18). Article 2303664. Cofiño-Fabres, C., Boonen, T., Rivera-Arbeláez, J. M., Rijpkema, M., Blauw, L., Rensen, P. C. N., Schwach, V., Ribeiro, M. C. & Passier, R.https://doi.org/10.1002/adhm.202303664Switching to external flows: Perturbations of developing vasculature within chicken chorioallantoic membrane (2024)Lab on a chip, 24, 3233-3242. Padmanaban, P., Galen, D. v., Salehi-Nik, N., Zakharova, M., Segerink, L. & Rouwkema, J.https://doi.org/10.1039/D4LC00311JAre monodisperse phospholipid-coated microbubbles “mono-acoustic?” (2024)Applied physics letters, 124(23). Article 231601. Spiekhout, S., van Elburg, B., Voorneveld, J., Jong, N. d., Versluis, M., Bosch, J. G. & Segers, T.https://doi.org/10.1063/5.0215736A safety screening platform for individualized cardiotoxicity assessment (2024)iScience, 27(3). Article 109139. Schwach, V., Slaats, R. H., Cofiño-Fabres, C., ten Den, S. A., Rivera-Arbeláez, J. M., Dannenberg, M., van Boheemen, C., Ribeiro, M., van der Zanden, S. Y., Nollet, E. E., van der Velden, J., Neefjes, J., Cao, L. & Passier, R.https://doi.org/10.1016/j.isci.2024.109139Alternative nano-lithographic tools for shell-isolated nanoparticle enhanced Raman spectroscopy substrates (2024)Nanoscale (E-pub ahead of print/First online). Srivastava, K., Jacobs, T. S., Ostendorp, S., Jonker, D., Brzesowsky, F. A., Susarrey-Arce, A., Gardeniers, H., Wilde, G., Weckhuysen, B. M., van den Berg, A., van der Stam, W. & Odijk, M.https://doi.org/10.1039/d4nr00428kElectrowetting assisted shedding of droplets by a shearing airflow in dropwise condensation (2024)International journal of heat and mass transfer, 220. Article 124925. Bonab, M. S., Wijnperle, D., Mugele, F., Kempers, R. & Amirfazli, A.https://doi.org/10.1016/j.ijheatmasstransfer.2023.124925Embedded macrophages induce intravascular coagulation in 3D blood vessel-on-chip (2024)Biomedical microdevices, 26(1). Article 2. Middelkamp, H. H. T., Weener, H. J., Gensheimer, T., Vermeul, K., Heus, L. E. d., Albers, H. J., Berg, A. v. d. & Meer, A. D. v. d.https://doi.org/10.1007/s10544-023-00684-wNanoscale Chemical Diversity of Coke Deposits on Nanoprinted Metal Catalysts Visualized by Tip-Enhanced Raman Spectroscopy (2024)Advanced materials, 36(5). Article 2305984. Filez, M., Walke, P., Le-The, H., Toyouchi, S., Peeters, W., Tomkins, P., Eijkel, J. C. T., De Feyter, S., Detavernier, C., De Vos, D. E., Uji-I, H. & Roeffaers, M. B. J.https://doi.org/10.1002/adma.202305984Fluorescent-Probe Characterization for Pore-Space Mapping with Single-Particle Tracking (2024)Angewandte Chemie, 136(4). Article e202314528. Mayorga Gonzalez, R., Maris, J. J. E., Wagner, M., Ganjkhanlou, Y., Bomer, J. G., Werny, M. J., Rabouw, F. T., Weckhuysen, B. M., Odijk, M. & Meirer, F.https://doi.org/10.1002/ange.202314528Fluorescent-Probe Characterization for Pore-Space Mapping with Single-Particle Tracking (2024)Angewandte Chemie (international edition), 63(4). Article e202314528. González, R. M., Maris, J. J. E., Wagner, M., Ganjkhanlou, Y., Bomer, J., Werny, M., Rabouw, F., Weckhuysen, B., Odijk, M. & Meirer, F.https://doi.org/10.1002/anie.202314528Acoustically Actuated Flow in Microrobots Powered by Axisymmetric Resonant Bubbles (2024)Advanced Intelligent Systems, 6(1). Article 2300465. Mohanty, S., Lin, Y.-H., Paul, A., van den Broek, M. R. P., Segers, T. & Misra, S.https://doi.org/10.1002/aisy.202300465

Conference article

High-Risk Human Papillomavirus Detection: Towards Multiplex Point-of-Care Detection of HPV Using an Easy-to-use Device (2024)IEEE sensors journal. van Dongen, J. E., Folkertsma-Hendriks, L., Steenbergen, R. D. M. & Segerink, L.

Conference contribution

CRISPR/Cas enabled sweat analysis: Paving the way for non-invasive point-of-care detection of pathogens by analyzing Cas12a trans-cleavage performance in Human sweat (2024)In IEEE biosensors proceedings . van Dongen, J. E., Moonen, E. J. M., Segerink, L. & den Toonder, J. M. J.Next-Generation ATR-IR Devices for Monitoring Chemical Processes (2024)In Next-Generation ATR-IR Devices for Monitoring Chemical Processes. Srivastava, K., Ramaswami, B., Veltkamp, H.-W., Boyle, N., Flaman, G., Bomer, J. G., van den Berg, A., van der Stam, W., Burgess, I. & Odijk, M.

PhD Thesis - Research UT, graduation UT

Everything, everywhere, all at once: Micro- and nano-fabrication for sensitive, homogeneous and spatio-temporally-resolved Raman and infrared spectroscopy sensors (2024)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Srivastava, K.https://doi.org/10.3990/1.9789036562171Instrumentation development for spectroscopy at the micro- and nanoscale (2024)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Jorissen, K. F. A.https://doi.org/10.3990/1.9789036561914

PhD Thesis - Research UT, graduation external

Catalyst pore space exploration using fluorescence and X-ray microscopy techniques (2024)[Thesis › PhD Thesis - Research UT, graduation external]. Utrecht University. Mayorga Gonzalez, R.https://doi.org/10.33540/2407

Preprint

Switching to external flows: perturbations of developing vasculature within chicken chorioallantoic membrane (2024)[Working paper › Preprint]. bioRxiv. Padmanaban, P., Galen, D. v., Salehi-Nik, N., Zakharova, M., Segerink, L. & Rouwkema, J.https://doi.org/10.1101/2024.01.11.575208

Review article

Prospects of nano-lithographic tools for the fabrication of surface-enhanced Raman spectroscopy (SERS) substrates (2024)Micro and Nano Engineering, 23. Article 100267. Srivastava, K., Le-The, H., Lozeman, J. J. A., van den Berg, A., van der Stam, W. & Odijk, M.https://doi.org/10.1016/j.mne.2024.100267Innovative electrode and chip designs for transendothelial electrical resistance measurements in organs-on-chips (2024)Lab on a chip, 24(5), 1121-1134. Holzreuter, M. & Segerink, L.https://doi.org/10.1039/D3LC00901G

2023

Abstract

MEMS-Based Microreactor for In Situ/Operando High-Resolution 3D X-Ray Microscopy of Single Catalyst Particles (2023)[Contribution to conference › Abstract] 28th North American Catalysis Society Meeting, NAM 2023. Carnevale, L., Broccoli, A., Mayorga Gonzalez, R., van Swieten, T. P., Groenesteijn, J., Ma, K., Wiegerink, R. J., Weckhuysen, B. M., Meirer, F., Olthuis, W. & Odijk, M.

Article

Controllable ingestion and release of guest components driven by interfacial molecular orientation of host liquid crystal droplets (2023)Journal of colloid and interface science, 652(Part A), 557-566. Yang, R., Deng, Y., Xie, S., Liu, M., Zou, Y., Qian, T., An, Q., Chen, J., Shen, S., van den Berg, A., Zhang, M. & Shui, L.https://doi.org/10.1016/j.jcis.2023.08.089Laser Controlled Manipulation of Microbubbles on a Surface with Silica-Coated Gold Nanoparticle Array (2023)Small, 19(49). Article 2302939. Li, X., Wang, F., Xia, C., The, H. L., Bomer, J. G. & Wang, Y.https://doi.org/10.1002/smll.202302939Droplet microreactor for high-throughput fluorescence-based measurements of single catalyst particle acidity (2023)Microsystems & nanoengineering, 9. Article 39. Vollenbroek, J. C., Nieuwelink, A.-E., Bomer, J. G., Tiggelaar, R. M., van den Berg, A., Weckhuysen, B. M. & Odijk, M.https://doi.org/10.1038/s41378-023-00495-2Mass production of lumenogenic human embryoid bodies and functional cardiospheres using in-air-generated microcapsules (2023)Nature communications, 14. Article 6685. van Loo, S. R., ten Den, S. A., Araújo-Gomes, N., de Jong, V., Snabel, R., Schot, M. R., Rivera Arbelaez, J. M., Veenstra, G. J., Passier, R., Kamperman, T. & Leijten, J.https://doi.org/10.1038/s41467-023-42297-0Accessibility study of porous materials at the single-particle level as evaluated within a microfluidic chip with fluorescence microscopy (2023)Chem Catalysis, 3(11). Article 100791. Broccoli, A., Carnevale, L., Mayorga Gonzalez, R., Dorresteijn, J. M., Weckhuysen, B. M., Olthuis, W., Odijk, M. & Meirer, F.https://doi.org/10.1016/j.checat.2023.100791In situ spatiotemporal characterization and analysis of chemical reactions using an ATR-integrated microfluidic reactor (2023)Lab on a chip, 23(21), 4690-4700. Srivastava, K., Boyle, N. D., Flaman, G. T., Ramaswami, B., Berg, A. v. d., Stam, W. v. d., Burgess, I. J. & Odijk, M.https://doi.org/10.1039/D3LC00521FDependence of sonoporation efficiency on microbubble size: An in vitro monodisperse microbubble study (2023)Journal of controlled release, 363, 747-755. van Elburg, B., Deprez, J., van den Broek, M., De Smedt, S. C., Versluis, M., Lajoinie, G., Lentacker, I. & Segers, T.https://doi.org/10.1016/j.jconrel.2023.09.047Tracking the dynamics of thrombus formation in a blood vessel-on-chip with visible-light optical coherence tomography (2023)Biomedical optics express, 14(11), 5642-5655. Cuartas Velez, C. A., Middelkamp, H. H. T., van den Berg, A., van der Meer, A. & Bosschaart, N.https://doi.org/10.1364/BOE.500434Microbubble formation by flow focusing: Role of gas and liquid properties, and channel geometry (2023)Journal of fluid mechanics, 972. Article A27. Cleve, S., Lassus, A., Diddens, C., Van Elburg, B., Gaud, E., Cherkaoui, S., Versluis, M., Segers, T. & Lajoinie, G.https://doi.org/10.1017/jfm.2023.704Coated microbubbles swim via shell buckling (2023)Communications Engineering, 2(1). Article 63. Chabouh, G., Mokbel, M., van Elburg, B., Versluis, M., Segers, T., Aland, S., Quilliet, C. & Coupier, G.https://doi.org/10.1038/s44172-023-00113-zLight-driven urea oxidation for a wearable artificial kidney (2023)Catalysis today, 419. Article 114163. Vollenbroek, J. C., Paradelo Rodriguez, A., Mei, B. T., Mul, G., Verhaar, M. C., Odijk, M. & Gerritsen, K. G. F.https://doi.org/10.1016/j.cattod.2023.114163Low-Variance Surface-Enhanced Raman Spectroscopy Using Confined Gold Nanoparticles over Silicon Nanocones (2023)ACS Applied Nano Materials, 6(11), 9657-9669. Jonker, D., Srivastava, K., Lafuente, M., Susarrey-Arce, A., van der Stam, W., van den Berg, A., Odijk, M. & Gardeniers, H. J. G. E.https://doi.org/10.1021/acsanm.3c01249Automated assessment of human engineered heart tissues using deep learning and template matching for segmentation and tracking (2023)Bioengineering and Translational Medicine, 8(3). Article e10513. Rivera-Arbeláez, J. M., Keekstra, D., Cofiño-Fabres, C., Boonen, T., Dostanic, M., ten Den, S. A., Vermeul, K., Mastrangeli, M., van den Berg, A., Segerink, L. I., Ribeiro, M. C., Strisciuglio, N. & Passier, R.https://doi.org/10.1002/btm2.10513Selective Evaporation at the Nozzle Exit in Piezoacoustic Inkjet Printing (2023)Physical review applied, 19(5). Article 054056. Rump, M., Sen, U., Jeurissen, R., Reinten, H., Versluis, M., Lohse, D., Diddens, C. & Segers, T.https://doi.org/10.1103/PhysRevApplied.19.054056Buckling of lipidic ultrasound contrast agents under quasi-static load (2023)Philosophical Transactions of the Royal Society of London A. Mathematical, Physical and Engineering Sciences, 381(2244). Article 20220025. Chabouh, G., Elburg, B. v., Versluis, M., Segers, T., Quilliet, C. & Coupier, G.https://doi.org/10.1098/rsta.2022.0025Oxygen gradient generator to improve in vitro modeling of ischemic stroke (2023)Frontiers in Neuroscience, 17. Article 1110083. Santiago, J., Kreutzer, J., Bossink, E., Kallio, P. & le Feber, J.https://doi.org/10.3389/fnins.2023.1110083C-Term Reduction in 3 μm Open-Tubular High-Aspect-Ratio Channels in AC-EOF Vortex Chromatography Operation (2023)Analytical chemistry, 95(11), 4889-4895. Westerbeek, E., Gelin, P., Olthuis, W., Eijkel, J. & De Malsche, W.https://doi.org/10.1021/acs.analchem.2c04547Microfluidic Impedance Cytometry for Single-Cell Particulate Inorganic Carbon:Particulate Organic Carbon Measurements of Calcifying Algae (2023)Global Challenges, 7(3). Article 2200151. de Bruijn, D. S., van de Waal, D. B., Helmsing, N. R., Olthuis, W. & van den Berg, A.https://doi.org/10.1002/gch2.202200151Supervised machine learning in microfluidic impedance flow cytometry for improved particle size determination (2023)Cytometry. Part A, 103(3), 221-226. de Bruijn, D., ten Eikelder, H., Papadimitriou, V., Olthuis, W. & van den Berg, A.https://doi.org/10.1002/cyto.a.24679Miniaturized Control of Acidity in Multiplexed Microreactors (2023)ACS Omega, 8(8), 7587-7594. Article 8. Balahkrishnan, D., El Maiss, J., Olthuis, W. & Pascual-García, C.https://doi.org/10.1021/acsomega.2c06897Nanoparticle Printing for Microfluidic Applications:: Bipolar Electrochemistry and Localized Raman Sensing Spots (2023)Micromachines, 14(2). Article 453. Broccoli, A., Vollertsen, A. R., Roels, P., van Vugt, A., van den Berg, A. & Odijk, M.https://doi.org/10.3390/mi14020453An optical aptasensor for real-time quantification of endotoxin: From ensemble to single-molecule resolution (2023)Science advances, 9(6). Article eadf5509. Zhu, P., Papadimitriou, V., van Dongen, J. E., Cordeiro, J., Neeleman, Y., Santoso, A., Chen, S., Eijkel, J. C. T., Peng, H., Segerink, L. & Rwei, A.https://doi.org/10.1126/sciadv.adf5509Multiplexed fluidic circuit board for controlled perfusion of 3D blood vessels-on-a-chip (2023)Lab on a chip, 23(1), 168-181. de Graaf, M. N. S., Vivas, A., Kasi, D. G., van den Hil, F. E., van den Berg, A., van der Meer, A. D., Mummery, C. L. & Orlova, V. V.https://doi.org/10.1039/d2lc00686c

Conference contribution

Labs and Organs on Chip for Health and Environment (2023)In 2023 IEEE Nanotechnology Materials and Devices Conference (NMDC) (pp. 570-570) (IEEE Nanotechnology Materials and Devices Conference (NMDC)). IEEE. van den Berg, A.https://doi.org/10.1109/NMDC57951.2023.10343667The effect of embedded macrophages on intravascular coagulation in 3D vessels-on-chips (2023)In Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023. Middelkamp, H. H. T., Weener, H. J., Gensheimer, T., Vermeul, K., de Heus, L. E., Albers, H. J., van den Berg, A. & van der Meer, A.

Meeting Abstract

Dependence of sonoporation efficiency on microbubble size: An in vitro monodisperse microbubble study (2023)The Journal of the Acoustical Society of America, 154(4_supplement), A277-A277. van Elburg, B., Deprez, J., Van den broek, M., De smedt, S., Versluis, M., Lajoinie, G., Lentacker, I. & Segers, T.https://doi.org/10.1121/10.0023517Disturbing bubbles in drop-on-demand piezo-acoustic inkjet printing (2023)The Journal of the Acoustical Society of America, 154(4_supplement), A109-A109. Versluis, M., Reinten, H., Fraters, A., Rump, M., Saade, Y., Diddens, C., Lohse, D. & Segers, T.https://doi.org/10.1121/10.0022952

Patent

Detection of cancer in urine (2023)[Patent › Patent]. Rurup, W. F., Segerink, L., van den Berg, A., Kraaijenhagen, R., Pinedo, H. M., Steenbergen, R. D. M., Nieuwenhuijzen, J. A., Bahce, I. & Kazemier, G.

PhD Thesis - Research UT, graduation UT

Microfluidic Impedance Cytometry for Single Sperm Analysis: Towards Morphology Characterization (2023)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Kruit, S. A.https://doi.org/10.3990/1.9789036558341Microfluidic vessels-on-chips for vascular disease modelling (2023)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Middelkamp, H. H. T.https://doi.org/10.3990/1.9789036557245Functional surface manipulation in micro- and nanofluidic devices (2023)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Yang, Y.https://doi.org/10.3990/1.9789036557764Following the dots: Versatile and modular approach for engineering and analyzing three-dimensional cardiac tissues (2023)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Rivera Arbeláez, J. M.https://doi.org/10.3990/1.9789036555272Microdevices for High-Throughput Screening of Single Catalyst Particles (2023)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Broccoli, A.https://doi.org/10.3990/1.9789036557528Microreactors for In Situ Single Catalyst Particle Characterization Using Advanced Imaging Techniques (2023)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Carnevale, L.https://doi.org/10.3990/1.9789036557566

Poster

Development of a Synovium-on-Chip Model with a Porous Membrane to Study Inflammatory Arthritis (2023)[Contribution to conference › Poster] NanoBioTech Montreux 2023. Spoelstra, L. R., Araújo-Gomes, N., Zakharova - Kolezhuk, M., Welting, T. J. M., Karperien, M., Segerink, L. & Le Gac, S.Fabrication of homogeneous shell-isolated sers substrates for catalytic applications (2023)[Contribution to conference › Poster] 27th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2023. Srivastava, K., Jacobs, T., Ostendorp, S., Jonker, D., Susarrey Arce, A., Gardeniers, H., Wilde, G., Weckhuysen, B. M., van den Berg, A., van der Stam, W. & Odijk, M.3D Porous Microfluidic Architectures for Heart-on-Chip (2023)[Contribution to conference › Poster] 27th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2023. Paul, A., van Dorp, T., Leferink, A. M., Vollertsen, A. R., van der Meer, A. & Odijk, M.Fabrication and Characterization of Plasmon-Active Infra-Red Enhanced Micromembranes for Gas Diffusion Studies (2023)[Contribution to conference › Poster] Micro and Nano Engineering Conference, MNE 2023. Srivastava, K., Lozeman, J. J. A., van den Berg, A., van der Stam, W. & Odijk, M.Digital Single Cancer Biomarker Detection Using CRISPR/Cas Sensing (2023)[Contribution to conference › Poster] CRISPR2023. van Dongen, J. E., Berendsen, J. T. W., Eijkel, J. C. T. & Segerink, L.High-throughput device for in situ study at millisecond spatiotemporal resolution of heterogeneous catalytic reactions at the single particle level with fluorescence microscopy. (2023)[Contribution to conference › Poster] 23rd Netherlands’ Catalysis and Chemistry Conference 2023 (Unpublished). Broccoli, A.

Review article

Use of 3D Printing Techniques to Fabricate Implantable Microelectrodes for Electrochemical Detection of Biomarkers in the Early Diagnosis of Cardiovascular and Neurodegenerative Diseases (2023)ACS Measurement Science Au, 3(5), 315-336. Zilinskaite, N., Shukla, R. P. & Baradoke, A.https://doi.org/10.1021/acsmeasuresciau.3c00028Portable, wearable and implantable artificial kidney systems: needs, opportunities and challenges (2023)Nature Reviews Nephrology, 19(8), 481-490. Ramada, D. L., de Vries, J., Vollenbroek, J., Noor, N., ter Beek, O., Mihăilă, S. M., Wieringa, F., Masereeuw, R., Gerritsen, K. & Stamatialis, D.https://doi.org/10.1038/s41581-023-00726-9

2022

Abstract

Effect of continuous electrical stimulation on engineered 3D cardiac tissues using hPSCs in a versatile platform (2022)[Contribution to conference › Abstract] NanoBioTech-Montreux Conference 2022. Rivera Arbelaez, J. M., Kutucu, C., Snippert, D., Dannenberg, M., Cofino Fabres, C., van den Berg, A., Ribeiro, M., Passier, R. & Segerink, L.Effect of dynamic, intracerebral-like, doxorubicin concentrations on brain stem cancer cells on-chip (2022)[Contribution to conference › Abstract] Microphysiological Systems World Summit, MPS 2022. Komen, J., van den Berg, A., van der Meer, A. & Van Vuurden, D.

Article

Selective Enrichment of Hypermethylated DNA by a Multivalent Binding Platform (2022)Advanced materials interfaces, 9(35). Article 2201557. Kolkman, R. W., Segerink, L. & Huskens, J.https://doi.org/10.1002/admi.202201557Vorticity-induced flow-focusing leads to bubble entrainment in an inkjet printhead: Synchrotron x-ray and volume-of-fluid visualizations (2022)Physical review fluids, 7(10). Article 104004. Rump, M., Saade, Y., Sen, U., Fezzaa, K., Versluis, M., Lohse, D. & Segers, T.https://doi.org/10.1103/PhysRevFluids.7.104004Density Control over MBD2 Receptor-Coated Surfaces Provides Superselective Binding of Hypermethylated DNA (2022)ACS applied materials & interfaces, 14(36), 40579-40589. Kolkman, R. W., Michel-Souzy, S., Wasserberg, D., Segerink, L. I. & Huskens, J.https://doi.org/10.1021/acsami.2c09641Label-Free Microfluidic Impedance Cytometry for Acrosome Integrity Assessment of Boar Spermatozoa (2022)Biosensors, 12(9). Article 679. Kruit, S. A., Bruijn, D. S. d., Broekhuijse, M. L. W. J., Olthuis, W. & Segerink, L. I.https://doi.org/10.3390/bios12090679Pressure-Driven Perfusion System to Control, Multiplex and Recirculate Cell Culture Medium for Organs-on-Chips (2022)Micromachines, 13(8). Article 1359. de Graaf, M. N. S., Vivas, A., van der Meer, A. D., Mummery, C. L. & Orlova, V. V.https://doi.org/10.3390/mi13081359Planar Junctionless Field-Effect Transistor for Detecting Biomolecular Interactions (2022)Sensors (Switzerland), 22(15). Article 5783. Shukla, R. P., Bomer, J. G., Wijnperle, D., Kumar, N., Georgiev, V. P., Singh, A. C., Krishnamoorthy, S., Pascual García, C., Pud, S. & Olthuis, W.https://doi.org/10.3390/s22155783Generation and Culture of Cardiac Microtissues in a Microfluidic Chip with a Reversible Open Top Enables Electrical Pacing, Dynamic Drug Dosing and Endothelial Cell Co-Culture (2022)Advanced Materials Technologies, 7(7). Article 2101355. Vivas, A., IJspeert, C., Pan, J. Y., Vermeul, K., van den Berg, A., Passier, R., Keller, S. S. & van der Meer, A. D.https://doi.org/10.1002/admt.202101355Time-resolved absolute radius estimation of vibrating contrast microbubbles using an acoustical camera (2022)The Journal of the Acoustical Society of America, 151(6), 3993-4003. Article 3993. Spiekhout, S., Voorneveld, J., Elburg, B. v., Renaud, G., Segers, T., Lajoinie, G. P. R., Versluis, M., Verweij, M. D., de Jong, N. & Bosch, J. G.https://doi.org/10.1121/10.0011619Systematic characterization of cleanroom-free fabricated macrovalves, demonstrating pumps and mixers for automated fluid handling tuned for organ-on-chip applications (2022)Microsystems & nanoengineering, 8. Article 54. Bossink, E. G. B. M., Vollertsen, A. R., Loessberg-Zahl, J. T., Meer, A. D. v. d., Segerink, L. I. & Odijk, M.https://doi.org/10.1038/s41378-022-00378-yApplication of generalized dispersion theory to vortex chromatography (2022)Journal of chromatography A, 1670. Article 462970. Westerbeek, E. Y., Gelin, P., Frankel, I., Olthuis, W., Eijkel, J. C. T. & De Malsche, W.https://doi.org/10.1016/j.chroma.2022.462970The Effect of Dynamic, In Vivo-like Oxaliplatin on HCT116 Spheroids in a Cancer-on-Chip Model Is Representative of the Response in Xenografts (2022)Micromachines, 13(5). Article 739. Komen, J., van Neerven, S., Bossink, E. G. B. M., de Groot, N., Nijman, L., van den Berg, A., Vermeulen, L. & van der Meer, A.https://doi.org/10.3390/mi13050739Contractility analysis of human engineered 3D heart tissues by an automatic tracking technique using a standalone application (2022)PLoS ONE, 17. Article e0266834. Rivera-Arbeláez, J. M., Cofiño-Fabres, C., Schwach, V., Boonen, T., ten Den, S. A., Vermeul, K., van den Berg, A., Segerink, L. I., Ribeiro, M. C. & Passier, R.https://doi.org/10.1371/journal.pone.0266834Resonance behavior of a compliant piezo-driven inkjet channel with an entrained microbubble (2022)The Journal of the Acoustical Society of America, 151(4), 2545-2557. Reinten, H., Jethani, Y., Fraters, A., Jeurissen, R., Lohse, D., Versluis, M. & Segers, T.https://doi.org/10.1121/10.0009784Fluidic circuit board with modular sensor and valves enables stand-alone, tubeless microfluidic flow control in organs-on-chips (2022)Lab on a chip, 22(6), 1231-1243. Vivas, A., van den Berg, A., Passier, R., Odijk, M. & van der Meer, A. D.https://doi.org/10.1039/d1lc00999kCeFlowBot: A Biomimetic Flow‐Driven Microrobot that Navigates under Magneto‐Acoustic Fields (2022)Small, 18(9). Article 2105829. Mohanty, S., Paul, A., Matos, P. M., Zhang, J., Sikorski, J. & Misra, S.https://doi.org/10.1002/smll.202105829A New Versatile Platform for Assessment of Improved Cardiac Performance in Human-Engineered Heart Tissues (2022)Journal of Personalized Medicine, 12(2). Article 214. Ribeiro, M. C., Rivera-Arbelaez, J. M., Cofino-Fabres, C., Schwach, V., Slaats, R. H., ten Den, S. A., Vermeul, K., van den Berg, A., Perez-Pomares, J. M., Segerink, L. I., Guadix, J. A. & Passier, R.https://doi.org/10.3390/jpm12020214A metastasis-on-a-chip approach to explore the sympathetic modulation of breast cancer bone metastasis (2022)Materials Today Bio, 13. Article 100219. Conceição, F., Sousa, D. M., Loessberg-Zahl, J., Vollertsen, A. R., Neto, E., Søe, K., Paredes, J., Leferink, A. & Lamghari, M.https://doi.org/10.1016/j.mtbio.2022.100219

Conference contribution

ATR microreactor: A tool for in-situ and spatial reaction monitoring (2022)In 2022 IEEE Sensors, SENSORS 2022 - Conference Proceedings (Proceedings of IEEE Sensors; Vol. 2022-October). IEEE. Srivastava, K., Boyle, N. D., Jorissen, K. F. A., Burgess, I. J., Van Der Stam, W., Van Den Berg, A. & Odijk, M.https://doi.org/10.1109/SENSORS52175.2022.9967095DNA-Origami Enabled Distance-Dependent Sensing (2022)In 2022 IEEE Sensors. IEEE. Dongen, J. E. V., Eijkel, J. C. T. & Segerink, L. I.https://doi.org/10.1109/SENSORS52175.2022.9967092Fabrication of Si-Au nanocone-nanoparticle array for homogeneous enhancement factor in Raman scattering (2022)In Plasmonics: Design, Materials, Fabrication, Characterization, and Applications XX. Article 121970A (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 12197). SPIE. Srivastava, K., Jonker, D., Lafuente, M., Susarrey-Arce, A., van den Berg, A., Gardeniers, H. J. G. E., van der Stam, W. & Odijk, M.https://doi.org/10.1117/12.2632955

Inaugural speech

Vruchtbare samenwerking op kleine schaal (2022)[Book/Report › Inaugural speech]. University of Twente. Segerink, L.

Paper

Digital single cancer biomarker detection by CRISPR/Cas sensing: Towards dynamic profiling for CpG methylation quantification (2022)[Contribution to conference › Paper] NanoBioTech-Montreux Conference 2022. van Dongen, J. E., Berendsen, J. T. W., Eijkel, J. C. T. & Segerink, L.An automated chip with a rapid prototypable cell culturing layer for multiplexed organs-on-chips (2022)[Contribution to conference › Paper] EUROoCS Annual Meeting 2022. Vollertsen, A. R., de Winter, S., van den Berg, A., Odijk, M. & van der Meer, A.Connecting labs for higher level organ-on-chip systems: integration of a pH sensor and a blood vessel-on-chip on a standardized platform (2022)[Contribution to conference › Paper] EUROoCS Annual Meeting 2022. Vollertsen, A. R., Aydogmus, H., Pollet, A., van Meer, B., van den Berg, A., Mastrangeli, M., Den Toonder, J., Odijk, M. & van der Meer, A.

PhD Thesis - Research UT, graduation UT

Enrichment of hypermethylated DNA on chip for cancer diagnostics (2022)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Kolkman, R. W.https://doi.org/10.3990/1.9789036554855Microfluidic and microengineered systems for automated cardiac organ-on-a-chip tissue culture (2022)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Vivas, A.https://doi.org/10.3990/1.9789036554930Novel Biosensors for Early Cancer Detection: Development of Gold Nanoparticle and CRISPR/Cas Assays for the Optical Detection of Cancer Biomarkers in Urine (2022)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. van Dongen, J. E.https://doi.org/10.3990/1.9789464586800Introducing vortex chromatography (2022)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Westerbeek, E.https://doi.org/10.3990/1.9789036554770Engineering a multiplexed Blood-Brain Barrier-on-a-chip (2022)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Zakharova, M.https://doi.org/10.3990/1.9789036554299Recreating the gut on-chip: Sensors and fabrication technologies for aerobic intestinal host – anaerobic microbiota research (2022)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Bossink, E. G. B. M.https://doi.org/10.3990/1.9789036553995Mimicking and surpassing the cancer xenograft model with dynamic, in vivo-like, drug concentrations on-chip (2022)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Komen, J.https://doi.org/10.3990/1.9789036553971Electrochemical reactions on-chip: Combinations with mass spectrometry for drug screening and proteomics (2022)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Führer, P.https://doi.org/10.3990/1.9789036553513

PhD Thesis - Research external, graduation UT

Microfluidic impedance cytometers for the study of single-cell calcifying algae (2022)[Thesis › PhD Thesis - Research external, graduation UT]. University of Twente. de Bruijn, D. S.https://doi.org/10.3990/1.9789036554480

Poster

A Blood-vessel-on-chip to characterize trained immunity in endothelial cells (2022)[Contribution to conference › Poster] EUROoCS Annual Meeting 2022. Le, K., Goosen - Middelkamp, H. H. T., Do, L., Netea, M., Jonkers, I., Orlova, V., Withoff, S., van der Meer, A. & Kumar, V.

2021

Article

The retraction of jetted slender viscoelastic liquid filaments (2021)Journal of fluid mechanics, 929. Article A25. Sen, U., Datt, C., Segers, T., Wijshoff, H., Snoeijer, J. H., Versluis, M. & Lohse, D.https://doi.org/10.1017/jfm.2021.855A Multiplexable Plasmonic Hairpin-DNA Sensor Based On Target-specific Tether Dynamics (2021)ACS sensors, 6(12), 4297–4303. van Dongen, J. E., Spoelstra, L. R., Berendsen, J. T. W., Loessberg-Zahl, J. T., Eijkel, J. C. T. & Segerink, L. I.https://doi.org/10.1021/acssensors.1c02097A CRISPR/Cas12a-assisted in vitro diagnostic tool for identification and quantification of single CpG methylation sites (2021)Biosensors & bioelectronics, 194. Article 113624. van Dongen, J. E., Berendsen, J. T. W., Eijkel, J. C. T. & Segerink, L. I.https://doi.org/10.1016/j.bios.2021.113624Nanotechnology for a Sustainable Future: Addressing Global Challenges with the International Network4Sustainable Nanotechnology (2021)ACS nano, 15(12), 18608-18623. Article 15. Pokrajac, L., Abbas, A., Chrzanowski, W., Dias, G. M., Eggleton, B. J., Maguire, S., Maine, E., Malloy, T., Nathwani, J., Nazar, L., Sips, A., Sone, J., van den Berg, A., Weiss, P. S. & Mitra, S. K.https://doi.org/10.1021/acsnano.1c10919Organ-on-Chip Technology for Aerobic Intestinal Host - Anaerobic Microbiota Research (2021)Organs-on-a-Chip, 4. Article 100013. Bossink, E. G. B. M., Segerink, L. & Odijk, M.https://doi.org/10.1016/j.ooc.2021.100013Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases (2021)Cardiovascular Research, 117(14), 2742-2754. Paloschi, V., Sabater-Lleal, M., Middelkamp, H., Vivas, A., Johansson, S., van der Meer, A., Tenje, M. & Maegdefessel, L.https://doi.org/10.1093/cvr/cvab088Self-Propelled Detachment upon Coalescence of Surface Bubbles (2021)Physical review letters, 127(23). Article 235501. Lv, P., Peñas, P., Le The, H., Eijkel, J., van den Berg, A., Zhang, X. & Lohse, D.https://doi.org/10.1103/PhysRevLett.127.235501High-throughput activity screening and sorting of single catalyst particles with a droplet microreactor using dielectrophoresis (2021)Nature Catalysis, 4(12), 1070-1079. Nieuwelink, A.-E., Vollenbroek, J. C., Tiggelaar, R. M., Bomer, J. G., Berg, A. v. d., Odijk, M. & Weckhuysen, B. M.https://doi.org/10.1038/s41929-021-00718-7Transwell-Integrated 2 µm Thick Transparent Polydimethylsiloxane Membranes with Controlled Pore Sizes and Distribution to Model the Blood-Brain Barrier (2021)Advanced Materials Technologies, 6(12). Article 2100138. Zakharova, M., Tibbe, M. P., Koch, L. S., Le-The, H., Leferink, A. M., van den Berg, A., van der Meer, A. D., Broersen, K. & Segerink, L. I.https://doi.org/10.1002/admt.202100138Virus removal from semen with a pinched flow fractionation microfluidic chip (2021)Lab on a chip, 21(22), 4477-4486. Hamacher, T., Berendsen, J. T. W., van Dongen, J. E., van der Hee, R. M., Cornelissen, J. J. L. M., Broekhuijse, M. L. W. J. & Segerink, L. I.https://doi.org/10.1039/D1LC00643FTime-resolved velocity and pressure field quantification in a flow-focusing device for ultrafast microbubble production (2021)Physical review fluids, 6(11). Article 114202. Cleve, S., Diddens, C., Segers, T., Lajoinie, G. & Versluis, M.https://doi.org/10.1103/PhysRevFluids.6.114202A potential micro-industrial plant for on-chip catalytic hydrogenation of organic liquid (2021)Journal of the Ghana Science Association, 20(1), 49-58. Doku, G. N., Verboom, W. & van den Berg, A.Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro (2021)Haematologica, 106(11). Hoefer, T., Rana, A., Niego, B., Jagdale, S., Albers, H. J., Gardiner, E. E., Andrews, R. K., Van der Meer, A. D., Hagemeyer, C. E. & Westein, E.https://doi.org/10.3324/haematol.2020.250761Meniscus Oscillations Driven by Flow Focusing Lead to Bubble Pinch-Off and Entrainment in a Piezoacoustic Inkjet Nozzle (2021)Physical review applied, 16(4). Article 044052. Fraters, A., Rump, M., Jeurissen, R., van den Berg, M., de Loore, Y., Reinten, H., Wijshoff, H., van der Meer, D., Lohse, D., Versluis, M. & Segers, T.https://doi.org/10.1103/PhysRevApplied.16.044052Asymmetric coalescence of two droplets with different surface tensions is caused by capillary waves (2021)Physical review fluids, 6(10). Article 104002. Hack, M. A., Vondeling, P., Cornelissen, M., Lohse, D., Snoeijer, J. H., Diddens, C. & Segers, T.https://doi.org/10.1103/PhysRevFluids.6.104002Detection of Spontaneous FeOOH Formation at the Hematite/Ni(Fe)OOH Interface during Photoelectrochemical Water Splitting by Operando X-ray Absorption Spectroscopy (2021)ACS catalysis, 11(19), 12324-12335. Ismail, A. S. M., Garcia-Torregrosa, I., Vollenbroek, J. C., Folkertsma, L., Bomer, J. G., Haarman, T., Ghiasi, M., Schellhorn, M., Nachtegaal, M., Odijk, M., van den Berg, A., Weckhuysen, B. M. & De Groot, F. M. F.https://doi.org/10.1021/acscatal.1c02566Determining Particle Size and Position in a Coplanar Electrode Setup Using Measured Opacity for Microfluidic Cytometry (2021)Biosensors, 11(10). Article 353. de Bruijn, D. S., Jorissen, K. F. A., Olthuis, W. & van den Berg, A.https://doi.org/10.3390/bios11100353Microfluidic Electrochemistry Meets Trapped Ion Mobility Spectrometry and High-Resolution Mass Spectrometry - In Situ Generation, Separation, and Detection of Isomeric Conjugates of Paracetamol and Ethoxyquin (2021)Analytical chemistry, 93(37), 12740-12747. Korzhenko, O., Führer, P., Göldner, V., Olthuis, W., Odijk, M. & Karst, U.https://doi.org/10.1021/acs.analchem.1c02791Inducing AC-electroosmotic flow using electric field manipulation with insulators (2021)Lab on a chip, 21(16), 3105-3111. Tiflidis, C., Westerbeek, E. Y., Jorissen, K. F. A., Olthuis, W., Eijkel, J. C. T. & De Malsche, W.https://doi.org/10.1039/d1lc00393cInhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions (2021)Cells, 10(8). Article 1998. Coenen, D. M., Heinzmann, A. C. A., Oggero, S., Albers, H. J., Nagy, M., Hagué, P., Kuijpers, M. J. E., Vanderwinden, J. M., van der Meer, A. D., Perretti, M., Koenen, R. R. & Cosemans, J. M. E. M.https://doi.org/10.3390/cells10081998Effect of surfactants on jet break-up in drop-on-demand inkjet printing (2021)Physics of Fluids, 33(7). Article 072112. Antonopoulou, E., Harlen, O. G., Rump, M., Segers, T. & Walkley, M. A.https://doi.org/10.1063/5.0056803Collagen I based enzymatically degradable membranes for organ-on-a-chip barrier models (2021)ACS biomaterials science & engineering, 7(7), 2998-3005. Arik, Y. B., De sa Vivas, A., Laarveld, D., Van Laar, N., Gemser, J., Visscher, T., van den Berg, A., Passier, R. & van der Meer, A. D.https://doi.org/10.1021/acsbiomaterials.0c00297Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release (2021)Journal of visualized experiments, 172. Article e62251. Nawijn, C., Segers, T., Lajoinie, G., Mørch, Ý., Berg, S., Snipstad, S., de Lange Davies, C. & Versluis, M.https://doi.org/10.3791/62251Highly parallelized human embryonic stem cell differentiation to cardiac mesoderm in nanoliter chambers on a microfluidic chip (2021)Biomedical microdevices, 23(2). Article 30. Vollertsen, A. R., Den, S. A. t., Schwach, V., van den Berg, A., Passier, R., van der Meer, A. D. & Odijk, M.https://doi.org/10.1007/s10544-021-00556-1Measuring barrier function in organ-on-chips with cleanroom-free integration of multiplexable electrodes (2021)Lab on a chip, 21(10), 2040-2049. Bossink, E. G. B. M., Zakharova, M., de Bruijn, D. S., Odijk, M. & Segerink, L. I.https://doi.org/10.1039/d0lc01289kOn-chip electrocatalytic NO sensing using ruthenium oxide nanorods (2021)Sensors and Actuators B: Chemical, 334. Article 129631. Tanumihardja, E., Paradelo Rodríguez, A., Loessberg-Zahl, J. T., Mei, B., Olthuis, W. & van den Berg, A.https://doi.org/10.1016/j.snb.2021.129631Fabrication of freestanding Pt nanowires for use as thermal anemometry probes in turbulence measurements (2021)Microsystems & nanoengineering, 7(1). Article 28. Le-The, H., Küchler, C., van den Berg, A., Bodenschatz, E., Lohse, D. & Krug, D.https://doi.org/10.1038/s41378-021-00255-0Feedback-controlled microbubble generator producing one million monodisperse bubbles per second (2021)Review of scientific instruments, 92(3). Article 035110. van Elburg, B., Collado-Lara, G., Bruggert, G.-W., Segers, T., Versluis, M. & Lajoinie, G.https://doi.org/10.1063/5.0032140Monitoring contractile cardiomyocytes via impedance using multipurpose thin film ruthenium oxide electrodes (2021)Sensors (Switzerland), 21(4). Article 1433. Tanumihardja, E., de Bruijn, D. S., Slaats, R. H., Olthuis, W. & van den Berg, A.https://doi.org/10.3390/s21041433Coccolithophore calcification studied by single-cell impedance cytometry: Towards single-cell PIC:POC measurements (2021)Biosensors & bioelectronics, 173. Article 112808. de Bruijn, D. S., ter Braak, P. M., van de Waal, D. B., Olthuis, W. & van den Berg, A.https://doi.org/10.1016/j.bios.2020.112808Microfluidic organ-on-a-chip model of the outer blood–retinal barrier with clinically relevant readouts for tissue permeability and vascular structure (2021)Lab on a chip, 21(2), 272-283. Arik, Y. B., Buijsman, W., Loessberg-Zahl, J. T., Cuartas Velez, C. A., Veenstra, C., Logtenberg, S., Grobbink, A. M., Bergveld, P., Gagliardi, G., den Hollander, A. I., Bosschaart, N., van den Berg, A., Passier, R. & van der Meer, A.https://doi.org/10.1039/d0lc00639dCell type-specific changes in transcriptomic profiles of endothelial cells, iPSC-derived neurons and astrocytes cultured on microfluidic chips (2021)Scientific reports, 11(1). Article 2281. Middelkamp, H. H. T., Verboven, A. H. A., de Sá Vivas, A. G., Schoenmaker, C., Klein Gunnewiek, T. M., Passier, R., Albers, C. A., 't Hoen, P. A. C., Nadif Kasri, N. & van der Meer, A. D.https://doi.org/10.1038/s41598-021-81933-xMeasuring both pH and O2 with a single on-chip sensor in cultures of human pluripotent stem cell-derived cardiomyocytes to track induced changes in cellular metabolism (2021)ACS sensors, 6(1), 267-274. Tanumihardja, E., Slaats, R. H., van der Meer, A. D., Passier, R., Olthuis, W. & van den Berg, A.https://doi.org/10.1021/acssensors.0c02282Combining Chemical Functionalization and FinFET Geometry for Field Effect Sensors as Accessible Technology to Optimize pH Sensing (2021)Chemosensors, 9(2), 1-12. Article 20. Rani, D., Rollo, S., Olthuis, W., Krishnamoorthy, S. & Pascual-García, C.https://doi.org/10.3390/chemosensors9020020Single Catalyst Particle Diagnostics in a Microreactor for Performing Multiphase Hydrogenation Reactions (2021)Faraday Discussions, 229, 267-280. Article 229. Nieuwelink, A.-E., Vollenbroek, J. C., Ferreira de Abreu, A., Tiggelaar, R. M., van den Berg, A., Odijk, M. & Weckhuysen, B. M.https://doi.org/10.1039/D0FD00006JAutonomous capillary microfluidic devices with constant flow rate and temperature-controlled valving (2021)Soft matter, 17(33), 7781-7791. Li, L., Westerbeek, E. Y., Vollenbroek, J. C., de Beer, S., Shui, L., Odijk, M. & Eijkel, J. C. T.https://doi.org/10.1039/D1SM00625H

Chapter

Particle Size Determination via supervised machine learning in microfluidic impendance spectroscopy (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10 - 14 October 2021, Palm Springs, CA, USA (pp. 1653-1654). de Bruijn, D. S., ten Eikelder, H. R. A., Papadimitriou, V., Olthuis, W. & van den Berg, A.

Conference contribution

3D Blood Vessels-on-Chip for atherosclerosis modelling (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 16931694) (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Middelkamp, H. H. T., van den Berg, A. & van der Meer, A. D.Automated medium recirculation using macro valves for high flow rates in an endothelial cell culture chip (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 1269-1270). Bossink, E. G. B. M., Vollertsen, A. R., Segerink, L., van der Meer, A. & Odijk, M.Calcification state of algae studied with impedance flow cytometry (2021)In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10 - 14 October 2021, Palm Springs, CA, USA (pp. 559-560). The Chemical and Biological Microsystems Society. de Bruijn, D. S., ter Braak, P. M., Van de Waal, D. B., Bomer, J. G., Olthuis, W. & van den Berg, A.Characterization of necrotic and viable spermatozoa in microfluidic impedance cytrometry (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10 - 14 October 2021, Palm Springs, CA, USA (pp. 549-550). Kruit, S. A., de Bruijn, D. S., Olthuis, W. & Segerink, L.Diffusion through single porous particle studied in a microfluidic system (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10 - 14 October 2021, Palm Springs, CA, USA (pp. 1223-1224). Carnevale, L., Gonzalez, R. M., Meirer, F., Olthuis, W., Weckhuysen, B. M. & van den Berg, A.Local deposition of nanoparticles on a PDMS Microfluidic device (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 1381-1382). Broccoli, A., Vollertsen, A. R., Roels, P., van Vugt, A., van den Berg, A. & Odijk, M.Microbial pathogen removal from porcine semen with acoustophoresis (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 255-256). Hamacher, T., Urbansky, A., Broekhuijse, M. L. W. J. & Segerink, L.Multiplexed Organ-on-Chips with integrated macro valves for automated cell culture (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2021 (pp. 1385-1386). Bossink, E. G. B. M., Vollertsen, A. R., Hagen , L. P., van der Meer, A., Segerink, L. & Odijk, M.Numerical study of acoustic streaming on the reduction of Taylor-Aris dispersion for chromatographic applications (2021)In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 1097-1098). The Chemical and Biological Microsystems Society. Gelin, P., Westerbeek, E., Eijkel, J. C. T., Olthuis, W., Maas, D. & De Malsche, W.Towards a multiplexed barcode CRISPR/Cas12a-Assisted platform for the identification and quantification of singele CpG Methylation Sites. (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10 - 14 October 2021, Palm Springs, CA, USA (pp. 741-742). van Dongen, J. E., Berendsen, J. T. W., Eijkel, J. C. T. & Segerink, L.Transient disruption of a Blood-brain Barrier on-chip using focused ultrasound and monodisperse microbubbles. (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10 - 14 October 2021, Palm Springs, CA, USA (pp. 477478). Zakharova, M., Persijn van Meerten, P. A. M., van den Broek, M. R. P., Segerink, L. & Segers, T. J.Virus removal from semen with a pinched-flow fractionation microfluidic chip (2021)In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10 - 14 October 2021, Palm Springs, CA, USA (pp. 1193-1194) (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences). The Chemical and Biological Microsystems Society. Hamacher, T., Berendsen, J. T. W., van Dongen, J. E., van der Hee, R. M., Cornelissen, J. J. L. M., Broekhuijse, M. L. W. J. & Segerink, L.Characterization of necrotic and viable spermatozoa in microfluidic impedance cytometry (2021)In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 549-550). The Chemical and Biological Microsystems Society. Kruit, S. A., de Bruijn, D. S., Olthuis, W. & Segerink, L. I.Diffusion through single porous particles studied in a microfluidic system (2021)In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1223-1224). The Chemical and Biological Microsystems Society. Carnevale, L., Gonzalez, R. M., Meirer, F., Olthuis, W., Weckhuysen, B. M. & van den Berg, A.Particle size determination via supervised machine learning in microfluidic impedance spectroscopy (2021)In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1653-1654). The Chemical and Biological Microsystems Society. de Bruijn, D. S., ten Eikelder, H. R. A., Papadimitriou, V. A., Olthuis, W. & van den Berg, A.

Dataset

Data for the article entitled: Ion Transport through Perforated Graphene (2021)[Dataset Types › Dataset]. 4TU.Centre for Research Data. Ghosh, M., Jorissen, K. F. A., Wood, J. A. & Lammertink, R. G. H.https://doi.org/10.4121/14013545

Paper

Dynamic inflammatory stimulation of hiPSC-endothelial cells in a multiplexed microfluidic chip (2021)[Contribution to conference › Paper] EUROoCS Annual conference 2021. Vollertsen, A. R., Le, K., van den Hil, L., Vermeul, K., van Meer, B., van den Berg, A., Orlova, V. V., Kumar, V., Odijk, M. & van der Meer, A.

PhD Thesis - Research UT, graduation UT

Semen Refinement: Microfluidic separation techniques for the removal of micro-organisms from semen for the veterinary industry (2021)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Hamacher, T.https://doi.org/10.3990/1.9789036552684Understanding wet age-related macular degeneration: an organ-on-a-chip model of the outer blood-retinal barrier (2021)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Arik, Y. B.https://doi.org/10.3990/1.9789036551670Electrochemical sensors for organ-on-chips: RuO2 for amperometric and potentiometric sensors (2021)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Tanumihardja, E.https://doi.org/10.3990/1.9789036551038Surface enhanced vibrational spectroscopy: Implementations in lab-on-a-chip (2021)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Lozeman, J. J. A.https://doi.org/10.3990/1.9789036550994Microfluidic devices functionalized with PNIPAm: Switchable wettability for reversible emulsion generation and capillary flow control (2021)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Li, L.https://doi.org/10.3990/1.9789036551779

Poster

Influence of acid treatment on the calcite exoskeleton of algae via impedance flow cytometry (2021)[Contribution to conference › Poster] NanoBioTech-Montreux 2021. de Bruijn, D. S., van de Waal, D., Olthuis, W. & van den Berg, A.Towards a Multiplexed Barcode CRISPR/Cas12a-Assisted Platform for the Identification and Quantification of Single CpG Methylation Sites (2021)[Contribution to conference › Poster] 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2021. van Dongen, J. E., Berendsen, J. T. W., Eijkel, J. C. T. & Segerink, L.Localized surface plasmon resonance based gold nanoparticle-hairpin assay for optical detection of single DNA molecules (2021)[Contribution to conference › Poster] 31st Anniversary World Congress on Biosensors, Biosensors 2021. van Dongen, J. E., Kolkman, R. W., Wasserberg, D., Knippenborg, L. V., Eijkel, J. C. T. & Segerink, L.A versatile platform that allows mechanical and electrical stimulation to improve maturation of hPSC-derived 3D engineered heart tissues (2021)[Contribution to conference › Poster] NanoBioTech-Montreux 2021. Rivera Arbelaez, J. M., Cofino Fabres, C., Boonen, T. M. P. M., Schwach, V., van den Berg, A., Segerink, L., Ribeiro, M. & Passier, R.Benchmarking the developmental stage of hPSCCMs upon stimulated maturation using a platform for 3D engineered heart tissues (2021)[Contribution to conference › Poster] EUROoCS Annual conference 2021. Cofino Fabres, C., Snabel, R., Rivera Arbelaez, J. M., Boonen, T. M. P. M., Ribeiro, M., Schwach, V., Veenstra, G. J. & Passier, R.Comparing on-chip colorectal cancer spheroid drug response to xenografts (2021)[Contribution to conference › Poster] EUROoCS Annual conference 2021. Komen, J., Bossink, E. G. B. M., van den Berg, A. & van der Meer, A.Engineering 3D vascularized heart tissues using hPSC derived cardiac cells (2021)[Contribution to conference › Poster] 11th World Congress on Alternatives and Animal Use in the Life Sciences 2021. Rivera Arbelaez, J. M., Ribeiro, M., Cofino Fabres, C., Schwach, V., Stein, J. M., Mummery, C. L., van den Berg, A., Segerink, L. & Passier, R.ForceTracker: A versatile tool for contractile force assessment in 3D Organ-on-Chip platforms (2021)[Contribution to conference › Poster] EUROoCS Annual conference 2021. Rivera Arbelaez, J. M., Dostanic, M., Stein, J. M., van den Berg, A., Segerink, L. I., Mummery, C. L., Sarro, P. M., Mastrangeli, M., Ribeiro, M. C. & Passier, R.Modeling cardiotoxicity utilizing human pluripotent stem cell-derived cardiomyocytes: towards protective therapy for the heart (2021)[Contribution to conference › Poster] EUROoCS Annual conference 2021. Schwach, V., Slaats, R. H., Cofino Fabres, C., ten Den, S. A., Rivera Arbelaez, J. M., Ribeiro, M., Cao, L. & Passier, R.Particle size determination in impedance flow cytometry using measured opacity (2021)[Contribution to conference › Poster] 21st International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2021. Jorissen, K. F. A., Olthuis, W. & van den Berg, A.

Preprint

Self-Propelled Detachment upon Coalescence of Surface Bubbles (2021)[Working paper › Preprint]. ArXiv.org. Lv, P., Peñas, P., The, H. L., Eijkel, J., van den Berg, A., Zhang, X. & Lohse, D.https://doi.org/10.48550/arXiv.2112.01157

Review article

Facilitating implementation of organs-on-chips by open platform technology (2021)Biomicrofluidics, 15(5). Article 051301. Vollertsen, A. R., Vivas, A., van Meer, B., van den Berg, A., Odijk, M. & van der Meer, A. D.https://doi.org/10.1063/5.0063428Bottom-Up Assembled Photonic Crystals for Structure-Enabled Label-Free Sensing (2021)ACS nano, 15(6), 9299-9327. Wang, J., Pinkse, P. W. H., Segerink, L. I. & Eijkel, J. C. T.https://doi.org/10.1021/acsnano.1c02495Mimicking and surpassing the xenograft model with cancer-on-chip technology (2021)EBioMedicine, 66. Article 103303. Komen, J., van Neerven, S. M., van den Berg, A., Vermeulen, L. & van der Meer, A. D.https://doi.org/10.1016/j.ebiom.2021.103303

Working paper

Fluidic Circuit Board with Modular Sensor and Valves Enables Stand-Alone, Tubeless Microfluidic Flow Control in Organs-on-Chips (2021)[Working paper › Working paper]. bioRxiv. Vivas, A., Berg, A. v. d., Passier, R., Odijk, M. & Meer, A. D. v. d.https://doi.org/10.1101/2021.11.24.469685

2020

Abstract

Effect of Microfluidic Processing on the Viability of Boar and Bull Spermatozoa (2020)[Contribution to conference › Abstract] 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2020. Hamacher, T., Berendsen, J. T. W., Kruit, S.-M. A., Broekhuijse, M. L. W. J. & Segerink, L.A modular microfluidic parallel dispensing system (2020)[Contribution to conference › Abstract] 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2020. de Boer, D., Vollertsen, A. R., van den Berg, A., van der Meer, A. & Odijk, M.

Article

Patterning Biological Gels for 3D Cell Culture inside Microfluidic Devices by Local Surface Modification through Laminar Flow Patterning (2020)Micromachines, 11(12). Article 1112. Loessberg-Zahl, J. T., Beumer, J., van den Berg, A., Eijkel, J. C. T. & van der Meer, A. D.https://doi.org/10.3390/mi11121112Modular microreactor with integrated reflection element for online reaction monitoring using infrared spectroscopy (2020)Lab on a chip, 20(22), 4166-4174. Lozeman, J. J. A., Elsbecker, T., Bohnenn, S., de Boer, H. L., Krakers, M., Mul, G., van den Berg, A. & Odijk, M.https://doi.org/10.1039/d0lc00704hReduction of Taylor-Aris dispersion by lateral mixing for chromatographic applications (2020)Lab on a chip, 20(21), 3938-3947. Westerbeek, E. Y., Bomer, J. G., Olthuis, W., Eijkel, J. C. T. & De Malsche, W.https://doi.org/10.1039/d0lc00773kPoint-of-care CRISPR/Cas nucleic acid detection: Recent advances, challenges and opportunities (2020)Biosensors & bioelectronics, 166(112445). Article 112445. van Dongen, J. E., Berendsen, J. T. W., Steenbergen, R. D. M., Wolthuis, R. M. F., Eijkel, J. C. T. & Segerink, L. I.https://doi.org/10.1016/j.bios.2020.112445Controlled pharmacokinetic anti-cancer drug concentration profiles lead to growth inhibition of colorectal cancer cells in a microfluidic device (2020)Lab on a chip, 20(17), 3167-3178. Komen, J., Westerbeek, E. Y., Kolkman, R. W., Roesthuis, J., Lievens, C., van den Berg, A. & van der Meer, A. D.https://doi.org/10.1039/d0lc00419gMultiplexed blood-brain barrier organ-on-chip (2020)Lab on a chip, 20(17), 3132-3143. Zakharova, M., Palma do Carmo, M. A., van der Helm, M. W., Le-The, H., de Graaf, M. N. S., Orlova, V., van den Berg, A., van der Meer, A. D., Broersen, K. & Segerink, L. I.https://doi.org/10.1039/d0lc00399aEffect of microfluidic processing on the viability of boar and bull spermatozoa (2020)Biomicrofluidics, 14(4). Article 044111. Hamacher, T., Berendsen, J. T. W., Kruit, S. A., Broekhuijse, M. L. W. J. & Segerink, L. I.https://doi.org/10.1063/5.0013919Plasmonic Nanocrystal Arrays on Photonic Crystals with Tailored Optical Resonances (2020)ACS applied materials & interfaces, 12(33), 37657-37669. Wang, J., Le-The, H., Karamanos, T., Suryadharma, R. N. S., van den Berg, A., Pinkse, P. W. H., Rockstuhl, C., Shui, L., Eijkel, J. C. T. & Segerink, L. I.https://doi.org/10.1021/acsami.0c05596Ballistic Energy Conversion with 78% Efficiency and System Integration (2020)Cell reports, 1(7). Article 100110. Xu, D., Duan, L., van den Berg, A., Eijkel, J. C. T. & Xie, Y.https://doi.org/10.1016/j.xcrp.2020.100110Determining the antioxidant properties of various beverages using staircase voltammetry (2020)Heliyon, 6(6). Article e04210. Schilder, W. H., Tanumihardja, E., Leferink, A. M., van den Berg, A. & Olthuis, W.https://doi.org/10.1016/j.heliyon.2020.e04210Mass Transport Determined Silica Nanowires Growth on Spherical Photonic Crystals with Nanostructure-Enabled Functionalities (2020)Small, 16(24). Article 2001026. Wang, J., Westerbeek, E. Y., van den Berg, A., Segerink, L. I., Shui, L. & Eijkel, J. C. T.https://doi.org/10.1002/smll.202001026In vitro microfluidic disease model to study whole blood-endothelial interactions and blood clot dynamics in real-time (2020)Journal of visualized experiments, 159. Article e61068. Manz, X. D., Albers, H. J., Symersky, P., Aman, J., van der Meer, A. D., Bogaard, H. J. & Szulcek, R.https://doi.org/10.3791/61068Trajectory Deflection of Spinning Magnetic Microparticles: The Magnus Effect at the Microscale (2020)Journal of Applied Physics, 127(19). Article 194702. Solsona, M., Keizer, H., de Boer, H. L., Klein, Y. P., Olthuis, W., Abelmann, L. & van den Berg, A.https://doi.org/10.1063/1.5145064Multilevel Spherical Photonic Crystals with Controllable Structures and Structure-Enhanced Functionalities (2020)Advanced Optical Materials, 8(10). Article 1902164. Wang, J., Le The, H., Shui, L., Bomer, J. G., Jin, M., Zhou, G., Mulvaney, P., Pinkse, P. W. H., van den Berg, A., Segerink, L. & Eijkel, J. C. T.https://doi.org/10.1002/adom.201902164Droplet encapsulation of electrokinetically-focused analytes without loss of resolution (2020)Lab on a chip, 20(12), 2209-2217. Papadimitriou, V., Kruit, S. A., Segerink, L. I. & Eijkel, J. C. T.https://doi.org/10.1039/D0LC00191KIncreasing the Sensitivity of Electrochemical DNA Detection by a Micropillar-Structured Biosensing Surface (2020)Langmuir, 36(16), 4272-4279. Movilli, J., Kolkman, R. W., Rozzi, A., Corradini, R., Segerink, L. I. & Huskens, J.https://doi.org/10.1021/acs.langmuir.0c00144Correction to "High Aspect Ratio Fin-Ion Sensitive Field Effect Transistor: Compromises toward Better Electrochemical Biosensing" (2020)Nano letters, 20(4), 2934-2934. Rollo, S., Rani, D., Leturcq, R., Olthuis, W. & García, C. P.https://doi.org/10.1021/acs.nanolett.0c01081A cardiomyocyte show of force: A fluorescent alpha-actinin reporter line sheds light on human cardiomyocyte contractility versus substrate stiffness (2020)Journal of molecular and cellular cardiology, 141, 54-64. Ribeiro, M. C., Slaats, R. H., Schwach, V., Rivera Arbelaez, J. M., Tertoolen, L. G. J., van Meer, B. J., Molenaar, R., Mummery, C. L., Claessens, M. M. A. E. & Passier, R.https://doi.org/10.1016/j.yjmcc.2020.03.008Comparative Analysis of Urine Fractions for Optimal Bladder Cancer Detection Using DNA Methylation Markers (2020)Cancers, 12(4). Article 859. Hentschel, A., Nieuwenhuijzen, J. A., Bosschieter, J., van Splunter, A. P., Lissenberg-Witte, B. I., van der Voorn, P., Segerink, L., van Moorselaar, R. J. A. & Steenbergen, R. D. M.https://doi.org/10.3390/cancers12040859Enhanced Protein Crystallization on Nafion Membranes Modified by Low-Cost Surface Patterning Techniques (2020)Crystal growth & design, 20(4), 2174-2186. Polino, M., Portugal, C. A. M., The, H. L., Tiggelaar, R., Eijkel, J., Crespo, J. G., Coelhoso, I. M., Pina, M. P. & Mallada, R.https://doi.org/10.1021/acs.cgd.9b00969Free Flow Ion Concentration Polarization Focusing (FF-ICPF) (2020)Analytical chemistry, 92(7), 4866–4874. Papadimitriou, V. A., Segerink, L. I. & Eijkel, J. C. T.https://doi.org/10.1021/acs.analchem.9b04526Flow-Free Microfluidic Device for Quantifying Chemotaxis in Spermatozoa (2020)Analytical chemistry, 92(4), 3302. Berendsen, J. T. W., Kruit, S. A., Atak, N., Willink, E. & Segerink, L.https://doi.org/10.1021/acs.analchem.9b05183Dimension-reconfigurable bubble film nanochannel for wetting based sensing (2020)Nature communications, 11(1). Article 814. Ma, Y., Sun, M., van den Berg, A., Eijkel, J. C. T. & Xie, Y.https://doi.org/10.1038/s41467-020-14580-xAg nano-assemblies on Si surface via CTAB-assisted galvanic reaction for sensitive and reliable surface-enhanced Raman scattering detection (2020)Sensors and Actuators B: Chemical, 304. Article 127224. Lu, H., Jin, M., Ma, Q., Yan, Z., Liu, Z., Wang, X., Akinoglu, E. M., van den Berg, A., Zhou, G. & Shui, L.https://doi.org/10.1016/j.snb.2019.127224Discharging behavior of confined bipolar electrodes: Coupled electrokinetic and electrochemical dynamics (2020)Electrochimica acta, 330. Article 135275. Eden, A., Scida, K., Arroyo-Currás, N., Eijkel, J. C. T., Meinhart, C. D. & Pennathur, S.https://doi.org/10.1016/j.electacta.2019.135275Exploring Voltage Mediated Delamination of Suspended 2D Materials as a Cause of Commonly Observed Breakdown (2020)The Journal of physical chemistry C, 124(1), 430-435. Loessberg-Zahl, J., de Bruijn, D. S., van den Beld, W. T. E., Dollekamp, E., Grady, E., Keerthi, A., Bomer, J., Radha, B., Zandvliet, H. J. W., Bol, A. A., van den Berg, A. & Eijkel, J. C. T.https://doi.org/10.1021/acs.jpcc.9b08500Modular operation of microfluidic chips for highly parallelized cell culture and liquid dosing via a fluidic circuit board (2020)Microsystems & nanoengineering, 6(1). Article 107. Vollertsen, A. R., de Boer, D., Dekker, S., Wesselink, B. A. M., Haverkate, R., Rho, H. S., Boom, R. J., Skolimowski, M., Blom, M., Passier, R., van den Berg, A., van der Meer, A. D. & Odijk, M.https://doi.org/10.1038/s41378-020-00216-zWafer-scale fabrication and modification of silicon nano-pillar arrays for nanoelectronics, nanofluidics and beyond (2020)International Journal of Nanotechnology, 17(7-10), 583-606. Jonker, D., Kooijman, L., Pordeli, Y., van der Wel, B., Berenschot, E., Borgelink, B., Le-The, H., de Boer, M., Eijkel, J., Hueting, R., Tiggelaar, R., van Houselt, A., Gardeniers, H. & Tas, N.https://doi.org/10.1504/IJNT.2020.111322

Comment/Letter to the editor

Erratum: Rayleigh-Taylor instability by segregation in an evaporating multicomponent microdroplet (Journal of Fluid Mechanics (2020) 899 (A22) DOI: 10.1017/jfm.2020.449) (2020)Journal of fluid mechanics, 908. Article E1. Li, Y., Diddens, C., Segers, T., Wijshoff, H., Versluis, M. & Lohse, D.https://doi.org/10.1017/jfm.2020.1076

Conference contribution

Versatile fabrication and integration method of optical oxygen sensors in organ-on-chips (2020)In 2020 IEEE sensors (IEEE SENSORS; Vol. 2020). IEEE. Bossink, E. G. B. M., Slob, J. V. M., Wasserberg, D., Segerink, L. & Odijk, M.https://doi.org/10.1109/SENSORS47125.2020.9278735High-performance ceramic EOF pump realized by massively parallel sacrificial silicon nano-pillar moulding (2020)In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sicences: uTAS 2019 (pp. 1188-1189). The Chemical and Biological Microsystems Society. Kooijman, L. J., Pordeli, Y., van der Wel, B. Y., Berenschot, J. W., Eijkel, J. C. T. & Tas, N. R.3D-Printing of a Lemon Battery via Fused Deposition Modelling and Electrodeposition (2020)In 2020 IEEE International Conference on Flexible and Printable Sensors and Systems (FLEPS). IEEE. Dijkshoorn, A., Šćulac, L., Sanders, R. G. P., Olthuis, W., Stramigioli, S. & Krijnen, G.https://doi.org/10.1109/FLEPS49123.2020.9239462Controlling AC-Electroosmotic vortex flows by shaping the channel cross section (2020)In 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2020): Proceedings of a meeting held 4-9 October 2020, Online (pp. 38-39). Article 0038. The Chemical and Biological Microsystems Society. Tiflidis, C., Westerbeek, E., Jorissen, K., Olthuis, W., Eijkel, J. & De Malsche, W.Measuring barrier function in a gut-on-chip (2020)In μTAS 2020: The 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 943-944). Bossink, E. G. B. M., Zakharova, M., Odijk, M. & Segerink, L.Highly parallelized human embryonic stem cell differentiation in nanoliter chambers (2020)In MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 861-862). The Chemical and Biological Microsystems Society. Vollertsen, A. R., ten Den, S. A., Schwach, V., van den Berg, A., Passier, R., van der Meer, A. D. & Odijk, M.Large-area fabrication of Au nanoantennas for surface enhanced infrared spectroscopy without an adhesion layer (2020)In Enhanced Spectroscopies and Nanoimaging 2020. Article 1146818 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 11468). SPIE. Lozeman, J. J. A., Srivastava, K., Le-The, H., van den Berg, A. & Odijk, M.https://doi.org/10.1117/12.2566757Magnetophoretic sorting of fluid catalytic cracking particles (2020)In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 1633-1634) (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society. Solsona, M., Nieuwelink, A.-E., Odijk, M., Meirer, F., Abelmann, L., Olthuis, W., Weckhuysen, B. M. & van den Berg, A.Optical accessibility imporvements for the characterization of the nanopede (2020)In MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 126-127). The Chemical and Biological Microsystems Society. de Kruiff, E. A. G., Kennedy, C. L., Tregouet, C. B. M., van Blaaderen, A., Eijkel, J. C. T. & Odijk, M.Overcoming mass transfer limitations by introducing vortex chromatography (2020)In 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2020): Proceedings of a meeting held 4-9 October 2020, Online (pp. 621-622). Article M2-233.d. The Chemical and Biological Microsystems Society. Westerbeek, E. Y., Gonzalez Amaya, G., Olthuis, W., Eijkel, J. C. T. & de Malsche, W.Synovial membrane on chip: a new tool to study co-culture response to mechanical stimulation (2020)In Proceedings of the 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020. Article Th8-854.e. Paggi, C. A., Zakharova, M., Segerink, L., le Gac, S., Moreira Teixeira Leijten, L. S. & Karperien, M.Using 3D-printing to fabricate a microfluidic vascular model to mimic arterial thrombosis (2020)In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 1070-1071). The Chemical and Biological Microsystems Society. Albers, H. J., Linssen, J. E. A., Costa, P. F., Middelkamp, H. H. T., van der Hout, L., Malda, J., Passier, R., van den Berg, A. & van der Meer, A. D.

Paper

Autonomous capillary microfluidic devices with constant flow rate and temperature-controlled valving (2020)[Contribution to conference › Paper] 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2020. Li, L., Westerbeek, E. Y., Vollenbroek, J. C., Shui, L., Odijk, M. & Eijkel, J. C. T.Ocean Carbon Cycle Studied by Single-cell Impedance Cytometry on Calcifying Algae (2020)[Contribution to conference › Paper] 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2020. de Bruijn, D. S., ter Braak, P. M., Van de Waal, D. B., Olthuis, W. & van den Berg, A.Optical accessibility improvements for the characterization of the Nanopede (2020)[Contribution to conference › Paper] 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2020. de Kruiff, E. A. G., Kennedy, C. L., Tregouet, C. B. M., van Blaaderen, A., Eijkel, J. C. T. & Odijk, M.

Patent

Microfluidic device for selection of semen (2020)[Patent › Patent]. de Wagenaar, B., Segerink, L., Olthuis, W., Sprenkels, A. J. & van den Berg, A.

PhD Thesis - Research UT, graduation UT

Modular, automated microfluidics for highly parallelized cell culture: An open, standardized platform approach to microfluidic stem cell differentiation (2020)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Vollertsen, A. R.https://doi.org/10.3990/1.9789036550734Thrombosis-on-a-Chip: Microfluidic Cell Culture Models with Whole Blood Perfusion (2020)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Albers, H. J.https://doi.org/10.3990/1.97890365497073D Hierarchical Particle Assemblies with Nanostructure-Enabled Functionalities (2020)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Wang, J.https://doi.org/10.3990/1.9789036549424Improving Organ on‐Chip Physiology: Exploring the barrier in blood‐brain barrier on‐chip systems (2020)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Tibbe, M. P.https://doi.org/10.3990/1.9789036549301Microreactors for single catalyst particle diagnostics: Measuring catalytic activity at high-throughput in multi-phase flows (2020)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Vollenbroek, J. C.https://doi.org/10.3990/1.9789036549325

Preprint

Trajectory Deflection of Spinning Magnetic Microparticles, the Magnus Effect at the Microscale (2020)[Working paper › Preprint]. Solsona, M., Keizer, H., de Boer, H., Klein, Y. P., Olthuis, W., Abelmann, L. & van den Berg, A.https://doi.org/10.48550/arXiv.2004.14264Plasmonic Bubble Nucleation and Growth in Water: Effect of Dissolved Air (2020)[Working paper › Preprint]. ArXiv.org. Li, X., Wang, Y., Zaytsev, M. E., Lajoinie, G., The, H. L., Bomer, J. G., Eijkel, J. C. T., Zandvliet, H. J. W., Zhang, X. & Lohse, D.https://doi.org/10.48550/arXiv.2002.00688

Review article

Organ-on-a-chip: The next generation platform for risk assessment of radiobiology (2020)RSC advances, 10(65), 39521-39530. Quan, Y., Sun, M., Tan, Z., Eijkel, J. C. T., Van Den Berg, A., Van Der Meer, A. & Xie, Y.https://doi.org/10.1039/d0ra05173jSpectroelectrochemistry, the future of visualizing electrode processes by hyphenating electrochemistry with spectroscopic techniques (2020)Analyst, 145(7), 2482-2509. Lozeman, J. J. A., Führer, P., Olthuis, W. & Odijk, M.https://doi.org/10.1039/c9an02105aUrea removal strategies for dialysate regeneration in a wearable artificial kidney (2020)Biomaterials, 234. Article 119735. van Gelder, M. K., Jong, J. A. W., Folkertsma, L., Guo, Y., Blüchel, C., Verhaar, M. C., Odijk, M., van Nostrum, C. F., Hennink, W. E. & Gerritsen, K. G. F.https://doi.org/10.1016/j.biomaterials.2019.119735

2019

Article

Tunable microstructured membranes in organs-on-chips to monitor transendothelial hydraulic resistance (2019)Tissue engineering. Part A, 25(23-24), 1635-1645. Das, P., van der Meer, A. D., Vivas, A., Arik, Y. B., Remigy, J. C., Lahitte, J. F., Lammertink, R. G. H. & Bacchin, P.https://doi.org/10.1089/ten.tea.2019.0021Application of Transmural Flow Across In Vitro Microvasculature Enables Direct Sampling of Interstitial Therapeutic Molecule Distribution (2019)Small, 15(46). Article 1902393. Offeddu, G. S., Possenti, L., Loessberg-Zahl, J. T., Zunino, P., Roberts, J., Han, X., Hickman, D., Knutson, C. G. & Kamm, R. D.https://doi.org/10.1002/smll.201902393Microfluidics and catalyst particles (2019)Lab on a chip, 19(21), 3575-3601. Solsona, M., Vollenbroek, J. C., Tregouet, C. B. M., Nieuwelink, A.-E., Olthuis, W., van den Berg, A., Weckhuysen, B. M. & Odijk, M.https://doi.org/10.1039/c9lc00318eContinuous focusing, fractionation and extraction of anionic analytes in a microfluidic chip (2019)Lab on a chip, 19(19), 3238-3248. Papadimitriou, V. A., Segerink, L. I. & Eijkel, J. C. T.https://doi.org/10.1039/c9lc00434cShape-defined solid micro-objects from poly(D,L-lactic acid) as cell-supportive counterparts in bottom-up tissue engineering (2019)Materials Today Bio, 4. Article 100025. Leferink, A. M., Tibbe, M. P., Bossink, E. G. B. M., de Heus, L. E., van Vossen, H., van den Berg, A., Moroni, L. & Truckenmüller, R. K.https://doi.org/10.1016/j.mtbio.2019.100025Scalable microphysiological system to model three-dimensional blood vessels (2019)APL Bioengineering, 3(2). Article 026105. de Graf, M. N. S., Cochrane, A., van den Hil, F. E., Buijsman, W., van der Meer, A., van den Berg, A., Mummery, C. L. & Orlova, V. V.https://doi.org/10.1063/1.5090986Fluorescence-Based Observation of Transient Electrochemical and Electrokinetic Effects at Nanoconfined Bipolar Electrodes (2019)ACS applied materials & interfaces, 11(14), 13777-13786. Scida, K., Eden, A., Arroyo-Currás, N., Mackenzie, S., Satik, Y., Meinhart, C. D., Eijkel, J. C. T. & Pennathur, S.https://doi.org/10.1021/acsami.9b01339Modeling Faradaic Reactions and Electrokinetic Phenomena at a Nanochannel-Confined Bipolar Electrode (2019)The Journal of physical chemistry C, 123(9), 5353-5364. Eden, A., Scida, K., Arroyo-Currás, N., Eijkel, J. C. T., Meinhart, C. D. & Pennathur, S.https://doi.org/10.1021/acs.jpcc.8b10473

Conference contribution

Diffusion from steady-state profile (DSSP) for low cost, low concentration measurement of diffusion (2019)In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences: uTAS 2019 (pp. 1530-1531). The Chemical and Biological Microsystems Society. Loessberg-Zahl, J. T., Gillrie, M., Kamm, R. D., van den Berg, A., van der Meer, A. & Eijkel, J. C. T.Ion concentration polarization for particle mesoporosity differentiation (2019)In 23rd International Conference on Miniaturized Systems for chemistry and Life Sciences: uTAS 2019 (pp. 1009-1010). The Chemical and Biological Microsystems Society. Papadimitriou, V., Solsona, M., Olthuis, W. & Eijkel, J. C. T.Microfluidic fabrication of hierarchical photonic crystal microspheres and their applications (2019)In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences: uTAS 2019 (pp. 154-155). The Chemical and Biological Microsystems Society. Wang, J., Le The, H., Shui, L., Bomer, J. G., Segerink, L. & Eijkel, J. C. T.On-demand droplet generator for extraction of electrokinetically focused analytes (2019)In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences: uTAS 2019 (pp. 977-978). The Chemical and Biological Microsystems Society. Papadimitriou, V., Kruit, S.-M. A., Segerink, L. & Eijkel, J. C. T.A microfluidic device for testing static and dynamic, in vivo like, drug concentration effects on cancer cells (2019)In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Komen, J., Westerbeek, E. Y., van der Meer, A. & van den Berg, A.Asessing barrier properties using impedance spectroscopy in a semi-circular, blood-brain barrier on-chip (2019)In Microtas 2019. Avgidis, F., Tibbe, M. P., Leferink, A. M. & Segerink, L.Assessing barrier properties using impedance spectroscopy in a semi-circular, blood-brain barrier on-chip (2019)In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 (pp. 422-423) (23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019). The Chemical and Biological Microsystems Society. Avgidis, F., Tibbe, M., Leferink, A. & Segerink, L.Electrokinetic enhancement of ion transport through changing membrane topology (2019)In 2019 AIChE Annual Meeting (AIChE Annual Meeting, Conference Proceedings; Vol. 2019-November). American Institute of Chemical Engineers. Benneker, A., Gumuscu, B., Derckx, E., Wood, J., Eijkel, J. & Lammertink, R.Ion concentration polarisation for particle mesoporosity differentiation (2019)In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 (pp. 1009-1010). The Chemical and Biological Microsystems Society. Papadimitriou, V. A., Solsona, M., Olthuis, W., van den Berg, A. & Eijkel, J. C. T.Multiplexed organ-on-chip device for increased throughput analysis of the tissue barrier function (2019)In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 (pp. 432-433). The Chemical and Biological Microsystems Society. Zakharova, M., van der Helm, M., do Carmo, M. P., Le-The, H., Tibbe, M., van der Meer, A., Broersen, K., Eijkel, J. & Segerink, L.The magnus force on spinning microparticles (2019)In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 (pp. 594-595). The Chemical and Biological Microsystems Society. Solsona, M., Keizer, H., de Boer, H. L., Klein, Y. P., Olthuis, W., Abelmann, L. & van den Berg, A.

Poster

Gold Nanoparticle Assays: A New Golden Standard for Optical DNA Detection (2019)[Contribution to conference › Poster] 7th CHemistry As INnovating Science Conference, CHAINS 2019. van Dongen, J. E., Le The, H., Kolkman, R. W., Wasserberg, D., Huskens, J., Eijkel, J. C. T. & Segerink, L.Algal carbon fixation studied by electrical impedance spectroscopy on single cells (2019)[Contribution to conference › Poster] NanoBioTech-Montreux 2019. de Bruijn, D. S., ter Braak, P. M., van de Waal, D., Olthuis, W. & van den Berg, A.Gold Nanoparticle Assays: A New Golden Standard for Optical DNA Detection (2019)[Contribution to conference › Poster] MESA+ Meeting 2019. van Dongen, J. E., Wasserberg, D., Eijkel, J. C. T. & Segerink, L. I.Designing and testing a microfluidic chip for sorting spermatozoa from somatic cells to shorten the handling time of testicular bioplsies for azoospermic males (2019)[Contribution to conference › Poster] ESHRE Annual Meeting. Berendsen, J. T. W., Meijer, H. A., Wetzels, A. & Segerink, L.Multiplexed organ-on-chip device for increased throughput analysis of the tissue barrier function (2019)[Contribution to conference › Poster] 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2019. Zakharova, M., van der Helm, M., Palma Do Carmo, M., Le The, H., Tibbe, M., van der Meer, A., Broersen, K., Eijkel, J. & Segerink, L.On-line impedimetric monitoring of single cell electrical lysis in a microfluidic device (2019)[Contribution to conference › Poster] 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2019. Sukas, S., van den Berg, A., Terstappen, L. & le Gac, S.S microfluidic device to investigate chemotactic behavior of spermatozoa (2019)[Contribution to conference › Poster] ESHRE Annual Meeting. Atak, N., Berendsen, J. T. W., Loessberg-Zahl, J. T. & Segerink, L. I.Separation of viruses from spermatozoa using a microfluidic chip to achieve pinched-flow fractionation (2019)[Contribution to conference › Poster] NanoBioTech-Montreux 2019. Hamacher, T., Berendsen, J. T. W., Broekhuijse, M. & Segerink, L.

Review article

The influence of geometry and other fundamental challenges for bio-sensing with field effect transistors (2019)Biophysical Reviews, 11(5), 757-763. Rollo, S., Rani, D., Olthuis, W. & Pascual-García, C.https://doi.org/10.1007/s12551-019-00592-5

2018

Article

Standardized and modular microfluidic platform for fast Lab on Chip system development (2018)Sensors and Actuators B: Chemical, 272, 468-478. Dekker, S., Buesink, W., Blom, M., Alessio, M., Verplanck, N., Hihoud, M., Dehan, C., César, W., Le Nel, A., van den Berg, A. & Odijk, M.https://doi.org/10.1016/j.snb.2018.04.005Ion Transport through Perforated Graphene (2018)The journal of physical chemistry letters, 9(21), 6339-6344. Ghosh, M., Jorissen, K. F. A., Wood, J. A. & Lammertink, R. G. H.https://doi.org/10.1021/acs.jpclett.8b02771Ruthenium oxide nanorods as potentiometric ph sensor for organs-on-chip purposes (2018)Sensors (Switzerland), 18(9). Article 2901. Tanumihardja, E., Olthuis, W. & van den Berg, A.https://doi.org/10.3390/s18092901Large-scale fabrication of free-standing and sub-μm PDMS through-hole membranes (2018)Nanoscale, 10(16), 7711-7718. Le-The, H., Tibbe, M., Loessberg-Zahl, J., Palma Do Carmo, M., van der Helm, M., Bomer, J., Van Den Berg, A., Leferink, A., Segerink, L. & Eijkel, J.https://doi.org/10.1039/c7nr09658e

Chapter

Capillary pinning assisted patterning of cell-laden hydrogel microarrays in microchips (2018)In Methods in Molecular Biology: Methods and Protocols (pp. 225-238) (Methods in Molecular Biology; Vol. 1771). Humana Press. Gumuscu, B. & Eijkel, J. C. T.https://doi.org/10.1007/978-1-4939-7792-5_18

Conference contribution

Microfluidic Construction of Hierarchical Composite Superballs for Sensing Application (2018)In Eurosensors 2018. MDPI. Wang, J., Shui, L., Segerink, L. & Eijkel, J. C. T.https://doi.org/10.3390/proceedings2130750Droplet microreactor for reaction monitoring at elevated temperatures and pressure (2018)In MicroTAS : 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences November 11-15, 2018, Kaohsiung, Taiwan (pp. 2131-2133). The Chemical and Biological Microsystems Society. Vollenbroek, J. C., Nieuwelink, A. E., Bomer, J. G., Tiggelaar, R. M., van den Berg, A., Weckhuysen, B. M. & Odijk, M.A miniaturized clark oxygen sensor for organ-on-chip devices (2018)In MicroTAS 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Science (pp. 889-892). The Chemical and Biological Microsystems Society. Bossink, E. G. B. M., Henry, O. Y. F., Benz, M. A., Segerink, L., Ingber, D. E. & Odijk, M.Construction of hierarchical microspheres with nanowrinkled surfaces and their application (2018)In MicroTAS 2018: The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 655-657). Wang, J., Segerink, L., Eijkel, J. C. T. & Shui, L.Continuous flow particle focusing by AC-actuation (2018)In MicroTAS 2018: The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1152-1154). The Chemical and Biological Microsystems Society. Tiflidis, C., Olthuis, W., Eijkel, J. & de Malsche, W.https://doi.org/10.13140/RG.2.2.22147.55848Free-flow depletion zone isotachophoresis (FFdz-ITP) (2018)In MicroTAS 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2013-2015). The Chemical and Biological Microsystems Society. Papadimitriou, V. A., van Zwol, R., Segerink, L. I. & Eijkel, J. C. T.Human induced pluripotent stem cell-derived endothelial cells in thrombosis-on-a-chip devices (2018)In MicroTas 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2392-2393). The Chemical and Biological Microsystems Society. Albers, H. J., da Silva Simão, J. P., Middelkamp, H. H. T., Mummery, C. L., Passier, R., van den Berg, A., Orlova, V. V. & van der Meer, A. D.Microdroplets in high temperature gradients generating porous catalytic microbeads (2018)In MicroTas 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1110-1113). The Chemical and Biological Microsystems Society. Tregouet, C., Bomer, J., Odijk, M., Lohse, D. & van den Berg, A.Modular ATR FT-IR microreactor chip for optimizing reaction conditions (2018)In MicroTAS 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2117-2120). The Chemical and Biological Microsystems Society. Lozeman, J. J. A., Vollenbroek, J. C., Bomer, J. G., de Boer, H. L., van den Berg, A. & Odijk, M.Spectroelectrochemical detection of p-benzoquinone and hydroquinone in an electrochemical microreator with an integrated ATR-IR IRE (2018)In MicroTAS 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2127-2130). The Chemical and Biological Microsystems Society. Führer, P., Lozeman, J. J. A., de Boer, H. L., Bomer, J. G., Olthuis, W. & Odijk, M.Standardized, Modular Parallelization Platform for Microfluidic Large-Scale Integration Cell Culturing Chips (2018)In MicroTAS 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2199-2201). The Chemical and Biological Microsystems Society. Vollertsen, A. R., Dekker, S., Wesselink, B. A. M., Haverkate, R., Bomer, J. G., Rho, H. S., Boom, R. J., Skolimowski, M., Blom, M., van der Meer, A., Passier, R., van den Berg, A. & Odijk, M.Gradual capacitance for particle tracking in micro-channels (2018)In MicroTAS 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, (pp. 99-101). The Chemical and Biological Microsystems Society. Solsona, M., Westerbeek, E., Olthuis, W. & van den Berg, A.

Other

Increasing the Efficiency of Motility Based Separation of Spermatozoa (2018)[Contribution to conference › Other] EMBS Micro and Nantechnology in Medicine Conference, MNMC 2018. Berendsen, J. T. W., Eijkel, J. C. T. & Segerink, L.

Poster

Porous sbum-micrometer PDMS membranes as cell culture substrates in a microfludiic chip (2018)[Contribution to conference › Poster] 9th International Conference on Microtechnologies in Medicine and Biology, MMB 2018. Tibbe, M. P., Le The, H., Leferink, A. M., Eijkel, J. C. T. & Segerink, L. I.Separation of spermatozoa from erythrocytes for testicular biopsies using tumbling mechanism in pinch flow fractionation (2018)[Contribution to conference › Poster] 9th International Conference on Microtechnologies in Medicine and Biology, MMB 2018. Berendsen, J. T. W., Eijkel, J. C. T. & Segerink, L. I.Transwell integrated porous sub-micrometer PDMS membranes as alternative cell culture platform (2018)[Contribution to conference › Poster] EMBS Micro and Nantechnology in Medicine Conference, MNMC 2018. Tibbe, M., Le The, H., Eijkel, J., van den Berg, A., Leferink, A. & Segerink, L.

Review article

The diagnostic accuracy of methylation markers in urine for the detection of bladder cancer: A systematic review (2018)Epigenomics, 10(5), 673-687. Bosschieter, J., Lutz, C., Segerink, L. I., Vis, A. N., Zwarthoff, E. C., van Moorselaar, R. J. A., van Rhijn, B. W. G., Heymans, M. W., Jansma, E. P., Steenbergen, R. D. M. & Nieuwenhuijzen, J. A.https://doi.org/10.2217/epi-2017-0156

2017

Article

Integrating Internal Standards into Disposable Capillary Electrophoresis Devices to Improve Quantification (2017)Analytical chemistry, 89(5), 2886-2892. Bidulock, A. C. E., Dubský, P., van den Berg, A. & Eijkel, J. C. T.https://doi.org/10.1021/acs.analchem.6b04172Improving the Resolution of 3D-Printed Molds for Microfluidics by Iterative Casting-Shrinkage Cycles (2017)Analytical chemistry, 89(4), 2227-2231. Sun, M., Xie, Y., Zhu, J., Li, J. & Eijkel, J. C. T.https://doi.org/10.1021/acs.analchem.6b05148Sensing oxygen at the millisecond time-scale using an ultra-microelectrode array (UMEA) (2017)Sensors and Actuators B: Chemical, 238, 1008-1016. van Rossem, F., Bomer, J. G., de Boer, H. L., Abbas, Y., de Weerd, E., van den Berg, A. & Le Gac, S.https://doi.org/10.1016/j.snb.2016.06.156Top-and-side dual-view microfluidic device with embedded prism (2017)Sensors and Actuators B: Chemical, 248, 753-760. Kazama, Y., Carlen, E. T., van den Berg, A. & Hibara, A.https://doi.org/10.1016/j.snb.2017.04.013

Conference contribution

Diffusiophoresis of gold in silica driven by the nanometric interfacial layer (2017)In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 269-270). The Chemical and Biological Microsystems Society. Tregouet, C., Le The, H., Odijk, M., Snoeijer, J., Eijkel, J., Lohse, D. & van den Berg, A.Electrical simulations and experimental results of 4-electrode AC transepithelial electrical resistance measurements in gut-on-a-chip (2017)In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1114-1115) (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society. van der Helm, M., Henry, O., Hamkins-Indik, T., Cronce, M., Leineweber, W., Odijk, M., van der Meer, A., Eijkel, J., Ingber, D. E., van den Berg, A. & Segerink, L.Continuous Extraction Depletion Zone Isotachophoresis (Edz-ITP) (2017)In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 58-59). The Chemical and Biological Microsystems Society. Papadimitriou, V. A., Segerink, L. I., van den Berg, A. & Eijkel, J. C. T.A gut-on-a-chip study: Enabling on-demand manipulation of the outer cell microenvironment in a multicompartmental 3D culture array (2017)In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1013) (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society. Gümüscü, B., Albers, H. J., van den Berg, A., Eijkel, J. & van der Meer, A. D.Chipholder-integrated 3d-printed pneumatic logic controllers for microfluidic chips (2017)In The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 645) (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS(; Vol. 2017). The Chemical and Biological Microsystems Society. Loessberg-Zahl, J., Vollenbroek, J., van der Meer, A., Eijkel, J. & van den Berg, A.Concentration polariztion to measure nano-pore accessibility (2017)In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 1497-1498) (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society. Solsona, M., Nieuwelink, A.-E., Papadimitriou, V. A., Eijkel, J. C. T., Meirer, F., Abelmann, L., Olthuis, W., Weckhuysen, B. M. & van den Berg, A.Configurable gel geometry via flow patterning for angiogenisis assays (2017)In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1074-) (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society. Loessberg-Zahl, J., Makkinga, D., van der Meer, A., Eijkel, J. & van den Berg, A.Large-area fabrication of sub-μm PDMS through hole membranes (2017)In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 375-376) (International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS); Vol. 2017). The Chemical and Biological Microsystems Society. Le-The, H., Palma do Carmo, M. A., van der Helm, M. W., Bomer, J. G., Segerink, L. I., van den Berg, A. & Eijkel, J. C. T.

Dataset

Desalination by Electrodialysis Using a Stack of Patterned Ion-Selective Hydrogels on a Microfluidic Device (2017)[Dataset Types › Dataset]. DATA Archiving and Networked Services (DANS). Benneker, A., Haase, A. S., Gümüscü Sefünc, B., Hempenius, M. A., van den Berg, A., Lammertink, R. G. H. & Eijkel, J. C. T.https://doi.org/10.4121/uuid:e7432dc5-0aee-4d2e-82a2-45d60166162e

Poster

A multiplexed organ-on-chip device with individually addressable channels (2017)[Contribution to conference › Poster] 2nd International Organ-on-Chip Symposium, IOOCS17, 2017. Palma Do Carmo, M., van der Helm, M. W., van der Meer, A., van den Berg, A., Eijkel, J. C. T. & Segerink, L.Reversible on-chip fabrication of a porous biopolymer membrane used for blood-brain barrier on-chip applications (2017)[Contribution to conference › Poster] 2nd International Organ-on-Chip Symposium, IOOCS17, 2017. Tibbe, M. P., van den Berg, A. & Segerink, L.

2016

Article

Potentiometric measurement with a Kelvin probe: Contactless measurement of chloride ions in aqueous electrolyte (2016)Sensors and Actuators B: Chemical, 236, 1126-1132. Abbas, Y., Zhu, X., de Boer, H. L., Tanvir, N. B., Olthuis, W. & van den Berg, A.https://doi.org/10.1016/j.snb.2016.06.150Self-assembled monolayers of 1-alkenes on oxidized platinum surfaces as platforms for immobilized enzymes for biosensing (2016)Applied surface science, 383, 283-293. Alonso, J. M., Bielen, A. A. M., Olthuis, W., Kengen, S. W. M., Zuilhof, H. & Franssen, M. C. R.https://doi.org/10.1016/j.apsusc.2016.05.006Oxidation and adduct formation of xenobiotics in a microfluidic electrochemical cell with boron doped diamond electrodes and an integrated passive gradient rotation mixer (2016)Lab on a chip, 16(20), 3990-4001. van den Brink, F. T. G., Wigger, T., Ma, L., Odijk, M., Olthuis, W., Karst, U. & van den Berg, A.https://doi.org/10.1039/c6lc00708b

Poster

A microfluidic platform to study the blood-brain barrier (2016)[Contribution to conference › Poster] 1st International Organ-on-chip symposium, IOOCS16. van der Helm, M., Frimat, J.-P., Odijk, M., van den Berg, A., Eijkel, J. & Segerink, L.Reversible on-chip fabrication of a porous biopolymer membrane used for blood-brain barrier on-chip applications (2016)[Contribution to conference › Poster] NanoBioTech-Montreux 2016. Tibbe, M. P., van den Berg, A. & Segerink, L.

Review article

Surface- and Tip-Enhanced Raman Spectroscopy in Catalysis (2016)The journal of physical chemistry letters, 7(8), 1570-1584. Hartman, T., Wondergem, C. S., Kumar, N., van den Berg, A. & Weckhuysen, B. M.https://doi.org/10.1021/acs.jpclett.6b00147

2015

Article

Microfluidic single sperm entrapment and analysis (2015)Lab on a chip, 15(5), 1294-1301. de Wagenaar, B., Berendsen, J. W. T., Bomer, J. G., Olthuis, W., van den Berg, A. & Segerink, L. I.https://doi.org/10.1039/c4lc01425a

Conference contribution

Connecting to concrete: wireless monitoring of chloride ions in concrete structures (2015)In Eurosensors 2015 (pp. 965-968) (Eurosensors; Vol. 120). Elsevier. Abbas, Y., ten Have, B., Hoekstra, G. I., Douma, A., de Bruijn, D., Olthuis, W. & van den Berg, A.https://doi.org/10.1016/j.proeng.2015.08.827

Editorial

Chip-based capillary electrophoresis platforms: Toward point-of-care applications (2015)Bioanalysis, 7(11), 1385-1387. Eijkel, J.https://doi.org/10.4155/bio.15.64

2014

Conference contribution

Towards paper-based point of care affinity proteomics (2014)In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 64-66). The Chemical and Biological Microsystems Society. Chinnasamy, T., Segerink, L. I., Nystrand, M., Gantelius, J. & Andersson Svahn, H.

Poster

A microfluidic platform to study and modulate the blood-brain barrier (2014)[Contribution to conference › Poster] EMBS Micro and Nanotechnology in Medicine Conference, MNMC 2014. van der Helm, M. W., Frimat, J.-P., Odijk, M., van den Berg, A. & Segerink, L.Microfluidic single sperm entrapment and analysis (2014)[Contribution to conference › Poster] EMBS Micro and Nanotechnology in Medicine Conference, MNMC 2014. de Wagenaar, B., Berendsen, J. T. W., Huisintveld, N., Olthuis, W., van den Berg, A. & Segerink, L.

2012

Article

Lab-on-a-chip technology for clinical diagnostics: The fertility chip (2012)Nederlands tijdschrift voor klinische chemie en laboratoriumgeneeskunde, 37(1), 61-63. Segerink, L. I., Sprenkels, A. J., Oosterhuis, G. J. E., Vermes, I. & Van Den Berg, A.https://www.nvkc.nl/sites/default/files/NTKC/2012-1-p61-p63.pdf

Poster

Label-free cell cycle analysis by impedance sensing (2012)[Contribution to conference › Poster] NanoBioTech-Montreux 2012. de Wagenaar, B., Segerink, L., Sprenkels, A. J. & van den Berg, A.

Review article

Riding the waves (2012)Lab on a chip, 12(14), 2433-2434. Van Den Berg, A.https://doi.org/10.1039/c2lc90065c

2011

Conference contribution

A cheap 2D fluorescence detection system for μM-sized beads on-chip (2011)In 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 (pp. 556-558). Segerink, L. I., Koster, M. J., Sprenkels, A. J., Vermes, I. & Van Den Berg, A.

2009

Chapter

Preface (2009)In Miniaturization and Mass Spectrometry (pp. V-VIII). Royal Society of Chemistry. le Gac, S. & van den Berg, A.https://pubs.rsc.org/en/content/chapter/bk9780854041299-fp005/978-0-85404-129-9

2008

Article

Viability analysis and apoptosis induction of breast cancer cells in a microfluidic device: effect of cytostatic drugs (2008)Biomedical microdevices, 10(08332/5), 727-737. Komen, J., Wolbers, F., Franke, H. R., Andersson, H., Vermes, I. & van den Berg, A.https://doi.org/10.1007/s10544-008-9184-5

Conference contribution

Quantum dots-based probes conjugated to Annexin V for photostable apoptosis detection and imaging (2008)In Colloidal Quantum Dots for Biomedical Applications III: SPIE BIOS, 19-24 January 2008 San Jose, California, United States. Article 68660I (Proceedings of SPIE; Vol. 6866). SPIE. Gac, S. L., Vermes, I. & Van Den Berg, A.https://doi.org/10.1117/12.787662

2007

Conference contribution

Design and optimization of fraction collector for capillary electrophoresis (2007)In Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 (pp. 1408-1410) (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007). The Chemical and Biological Microsystems Society. Zalewski, D. R., Schlautmann, S., Schasfoort, R. B. M. & Gardeniers, H. J. G. E.Sonoporation with single bubbles in microfluidic systems (2007)In 6th International Symposium on Therapeutic Ultrasound: 30 August-2 September 2006, Oxford (United Kingdom) (pp. 492-497) (AIP Conference Proceedings; Vol. 911). American Institute of Physics. Le Gac, S., Zwaan, E., van den Berg, A. & Ohl, C.-D.https://doi.org/10.1063/1.2744319

2006

Paper

Influence of apoptotic cells on macrophages and induction of phagocytosis studied in PDMS microchips using photostable staining (2006)[Contribution to conference › Paper] 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2006. Le Gac, S., Vermes, I. & Van Den Berg, A.

Patent

Biochip and process for the production of a biochip (2006)[Patent › Patent]. Bomer, J. G., Sprenkels, A. J., Ingham, C. J., van Hylckama Vlieg, J. E. T., de Vos, W. M. & van den Berg, A.https://patents.google.com/patent/WO2006112709A2/HIGH THROUGHPUT SCREENING METHOD FOR ASSESSING HETEROGENEITY OF MICROORGANISMS (2006)[Patent › Patent]. Ingham, C., De Vos, Willem, M., van Hylckama Vlieg, J., Bomer Johan, G., Sprenkels Adrianus, J. & Van Den Berg,, A.High throughput screening method for assessing heterogeneity of microorganisms (2006)[Patent › Patent] (Submitted). Ingham, C. J., Sprenkels, A., van Hylckama Vlieg, J. E. T., Bomer, J., de Vos, W. M. & van den Berg, A.https://patents.google.com/patent/WO2006112709A2/

2000

Article

Evanescent wave sensing: new features for detection in small volumes (2000)Sensors and Actuators A: Physical, 85(1-3), 158-162. Pandraud, G., Koster, T. M., Gui, C., Dijkstra, M., van den Berg, A. & Lambeck, P.https://doi.org/10.1016/S0924-4247(00)00367-8

1999

Poster

Development of an Analytical System for Real Time Monitoring of Fermentation and Cell Culture Processes Based on Micro-Chip and Conventional Capillary Electrophoresis and Capillary Electrochromatography (1999)[Contribution to conference › Poster] 12th International Symposium on High Performance Capillary Electrophoresis and Related Microscale Techniques 1999. Billiet, H. A. H., Macka, M., Haddad, P. R., Fowler, P., Frank, J., van Dedem, G. W. K., Fintschenko, Y. & van den Berg, A.

1990

Article

Modification of ISFESTs by covalent anchoring of poly(hydroxyethyl methacrylate) hydrogel. Introduction of a thermodynamically defined semiconductor-sensing membrane interface (1990)Analytica chimica acta, 230(3), 59-65. Sudhölter, E. J. R., van der Wal, P. D., Skowronska-Ptasinska, M., van den Berg, A., Bergveld, P. & Reinhoudt, D. N.https://doi.org/10.1016/S0003-2670(00)82761-0New membrane materials for potassium-selective ion-sensitive field-effect transistors (1990)Analytica chimica acta, 231(4), 41-52. van der Wal, P. D., Skowronska-Ptasinska, M., van den Berg, A., Bergveld, P., Sudhölter, E. J. R. & Reinhoudt, D. N.https://doi.org/10.1016/S0003-2670(00)86395-3
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