Dr.ir .F.F.J. (Frank) Simonis

Assistant professor
Room: Carré 3621
Phone: +31 53 489 2944
E-mail: f.f.j.simonis@utwente.nl


Frank Simonis studied Biomedical Engineering at the Eindhoven University of Technology (TU/e). His Master’s program included many MR related courses and during that time he did an internship on the magnetic susceptibility of water at the ETH Zürich in the group of professor Pruessmann. He graduated from the TU/e in 2011 on research in the group of professor Nicolay focused on a novel method to obtain T2 maps of the mouse heart. After obtaining his Master’s degree he started his PhD at the University Medical Centre of Utrecht under professor Jan Lagendijk with supervision of dr. Nico van den Berg. In his PhD project the body's physiological response to local RF heating caused by MR measurements was investigated. The capacity of the body to regulate temperature at a local scale (e.g. by elevation of local blood flow) is largely unknown and was a main topic of his research. Next to that, he did research on improving the estimation of the arterial input function, which is an important parameter in dynamic contrast enhanced MRI. He currently teaches MRI and researches new applications of low-field MRI as assistant professor in the Magnetic Detection group.


MRI, low-field, MR imaging in upright position


  • Beeldvormende Technieken
  • Imaging Techniques


  • Simonis FFJ, Raaijmakers AJE, Lagendijk JJW, van den Berg CAT, “Validating subject-specific RF and thermal simulations in the calf muscle using MR-based temperature measurements”, Magnetic Resonance in Medicine 2016, April 27, doi:10.1002/mrm.26244
    [Epub ahead of print]
  • Simonis FFJ, Sbrizzi A, Beld E, Lagendijk JJW, van den Berg CAT, “Improving the arterial input function in dynamic contrast enhanced MRI by fitting the signal in the complex plane”, Magnetic Resonance in Medicine 2016, October;76(4):1236-45; doi: 10.1002/mrm.26023
  • Simonis FFJ, Petersen ET, Lagendijk JJW, van den Berg CAT, “Feasibility of measuring thermoregulation during RF heating of the human calf muscle using MR based methods”, 
    Magnetic Resonance in Medicine 2016, April;75(4):1743-51 doi: 10.1002/mrm.25710 
  • Simonis FFJ, Petersen ET, Bartels LW, Lagendijk JJW, van den Berg CAT, “Compensating for magnetic field inhomogeneity in multigradient-echo-based MR thermometry”, 
    Magnetic Resonance in Medicine 2015, March;73(3):1184-9; doi: 10.1002/mrm.25207
  • Coolen BF, Simonis FFJ, Geelen T, Moonen RP, Arslan F, Paulis LE, Nicolay K, Strijkers GJ, “Quantitative T2 mapping of the mouse heart by segmented MLEV phase-cycled T2 preparation”, Magnetic Resonance in Medicine 2014, August;72(2):409-17; 
    doi: 10.1002/mrm.24952