Former master assignements

FORMER STUDENTS

Emese van Dalen, BSc

Biomedical Engineering, Physiological Signals & Systems, University of Twente
Contact: emesevandalen@hotmail.com / https://www.linkedin.com/in/emese-van-dalen/
September 2023 - April 2024

 Assignment
Hypotension is a common complication during or shortly after the anaesthesia induction, referred to as post-induction hypotension. My research aims to predict post-induction hypotension based on patient and surgery characteristics and medication and physiological data using Machine Learning models. The ultimate goal is to utilize the predictive model as a decision support tool for the anaesthesiologist, improving patient safety. 

Collaborating partner
Medisch Spectrum Twente Enschede - Anesthesiology

Committee
Prof. Dr. D. W. Donker (Chair)
Dr. J.W. Potters (Daily (medical) supervisor UT)
M.P. Mulder, MSc (Daily (technical) supervisor UT)
Dr. M. Poel (External supervisor UT)
Drs. R.M. Krol (Process supervisor)


Mirjam Markusse, BSc

Technical Medicine, Medical Sensing & Stimulation, University of Twente
Contact: m.markusse@student.utwente.nl
August 2022 - September 2023

Assignment
Though hypotension is common during surgery, its treatment is of more reactive than preventive in nature. My research focuses on advanced signal analysis and machine learning methods to predict hypotension, and guide haemodynamic management in the operating room.

Collaborating partner
Medisch Spectrum Twente Enschede - Anesthesiology

Committee
Prof. Dr. D. W. Donker (Chair)
Dr. J.W. Potters (Medical supervisor)
Dr. L. Fresiello (Technological supervisor UT)
M.P. Mulder, MSc (Technological supervisor UT)
Drs. R.M. Krol (Process supervisor)


Maaike Wösten, BSc

Technical Medicine, Medical Sensing & Stimulation, University of Twente
Applied Mathematics, Systems, Analysis and Computational Sciences
Contact: http://www.linkedin.com/in/maaike-wösten-152b6a153
September 2022 - October 2023

Assignment
To improve the clinical management of patients supported with VA-ECMO, it is important to continuously monitor the condition of the heart. The heart and the VA-ECMO circuit both contribute to the patient’s hemodynamics. This complicates monitoring the condition of the heart accurately. Therefore, in this research, we aim to describe the contribution of the native heart using cardiovascular models and clinical data.

Collaborating partner
University Medical Centre Utrecht, Intensive Care Centrum
Research Group: Mathematics of Systems Theory, University of Twente

Committee
Prof. Dr. H. Zwart (Chair)
Prof. Dr. D. W. Donker (Medical supervisor) 
Dr. L. Fresiello (Technological supervisor UT)
Dr. Lisette M. Vernooij (Additional supervisor)
Drs. R.M. Krol (Process supervisor)


Wibrich Boskma, BSc

Technical Medicine, Medical Sensing & Stimulation, University of Twente
Applied Mathematics, Systems, Analysis and Computational Sciences
Contact: www.linkedin.com/in/wibrich-boskma
October 2022 – October 2023

Assignment
This research aims to develop and validate a bedside stand-alone device to measure functional residual capacity in mechanical ventilated children as a tool to assess their pulmonary status and the effect of ventilator settings. With the results, a decision support model can be designed to improve ventilation settings, lung recruitment and clinical practice in the paediatric intensive care unit.

Collaborating partner
University Medical Centre Groningen – Paediatric Intensive Care Unit

Committee
Prof. Dr. D. W. Donker (Chair)
Dr. M.C.J. Kneyber, MD PhD FCCM  (Medical supervisor)
Drs. R.G.T. Blokpoel  (Medical supervisor)
A.A. Koopman, MSc.  (Technical medicinal supervisor)
Dr. E. Mos-Oppersma  (Technical supervisor UT)
Drs. J. de Witte  (Process supervisor)


Marit Bot, BSc

Technical Medicine, Medical Sensing & Stimulation, University of Twente
Contact: https://www.linkedin.com/in/marit-bot-745b74222/
Jan 2023 – Dec 2023

Assignment
Discovering underlying markers in the identification of sepsis. Using waveforms measured at the Emergency Department as input for an unsupervised deep learning model, I aim to uncover clusters of sepsis patients and relate the findings.

Collaborating partner
University Medical Centre Groningen – Emergency Room

Committee
Prof. Dr. D. W. Donker (Chair)
Prof. Dr. J.C. ter Maaten (Medical Supervisor)
M.P. Mulder, MSc (Technological supervisor UT)
Drs. J. de Witte (Process supervisor)


Gerwin Numan, BSc

Biomedical Engineering, Medical Device Design, University of Groningen
Contact : g.k.numan@utwente.nl or g.k.numan@student.rug.nl
February 2023 - July 2023

Assignment
The goal is to develop a 3D anatomical model of the aorta which can be attached to the in silico- in vitro blood circulation simulator. By creating a compliant aorto, which can be attached to the simulator, investigations on  Extracorporeal Membrane Oxygenation (ECMO) therapy can be performed. When the pump of the ECMO is inserted into the aorta, the setup can be altered to mimic patient specific conditions, investigate patient-device interactions, measure the region of collision, flow pattern and flow development during ECMO treatment. 

Committee
dr. ir. L. Fresiello (Daily Supervisor UT)
dr. ir. R. Fluit (First Examiner, University of Groningen)
Prof. Dr. D. W. Donker (Second Examiner, University of Twente


Anna Schoonhoven, BSc
Technical Medicine, Medical Sensing & Stimulation, University of Twente
Contact: https://www.linkedin.com/in/anna-schoonhoven-50692b160/
January 2022 - December 2022

Assignment
Accurate identification of sepsis and prediction of patients at risk is essential to improve treatment. In this research, I try to predict sepsis within 48 hours among patients with early sepsis in the Emergency Room, based on several features from waveforms derived from EMG and PPG wearables with machine-learning methods.

Collaborating partner
University Medical Centre Groningen - Emergency Room

Committee
Prof. Dr. Ir. H.J. Hermens (Chair)
Prof. Dr. J.C. ter Maaten (Medical supervisor)
Prof. Dr. D. W. Donker (Technological supervisor UT)
M.P. Mulder, MSc (Technological supervisor UT)
dr. M. Groenier (Process supervisor)