Prof. Passier envisions the development of contracting and fluid-pumping mini-hearts that closely mimic the developmental, structural, and functional characteristics of human hearts, both in health and disease. His goal is to establish a screening platform for target identification and validation, capturing the diversity of patient responses. This innovative strategy aims to unlock new therapeutic opportunities and create better, safer drugs for treating heart disease. By developing predictable human heart models, we can significantly decrease the use of animals in experimental research, promoting ethical practices in the scientific community.
Discover how mini hearts-on-chips can transform cardiovascular disease treatment, reducing reliance on animal testing while advancing innovative human heart models.
