BRAIN- SHIFT

Brain-SHIFT an innovative AI tool to select Subdural Hematoma Invasive or Follow-up Treatment

Organization:

Funded by:	Pioneers in Healthcare Innovation Fund 2022
Postdoc:	Elina Tibeau-Sutre  elina.ts@free.fr Connect with me on LinkedIn
Supervisors:	chair MIA: prof.dr. C. Brune (Christoph) Full Professor +31534893384  c.brune@utwente.nl Building: Zilverling 2061 Personal page Daily supervisor: dr. J.M. Wolterink (Jelmer) Assistant Professor +31534895949  j.m.wolterink@utwente.nl Building: Zilverling 2063 Personal page
Collaboration:	Dr. Kho (Enschede, MST webpage Jorieke Reimer AIOS neurologie MST Connect with me on LinkedIn

Description:

The midline shift is a well-known measurement used in the clinical routine to estimate the deformation of the pathological brain, particularly in the case of a chronic subdural hematoma. However, this measurement is local and does not reflect the pressure encountered by all neurological regions. Then there is an unmet need for new measurements considering the deformation of all parts of the brain. 

The aim of this project is to develop a method to estimate the deformation field encountered by the whole brain when a hematoma is growing in the skull, which is a constrained space. First, anatomical landmarks such as the skull, the midplane of the brain and the hematoma volume will be automatically computed. Then, they will be used by a deep learning network learning to estimate a clinically relevant brain deformation field: a deformation field that allows to estimate a pseudo-healthy scan from the original one.

Ultimately this study will allow to develop new measurements that could be used by the clinical team to decide which treatment should be given to patients with chronic subdural hematomas.

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