3. IVY: Implicit improvement of vitality in breast cancer patients

Winner of the Roche Patient Innovation Award 2019


Fatigue, vitality, self-concept bias, cognitive bias modification


More than 50% of all breast cancer patients experience fatigue symptoms during and after their treatment course. Recent evidence shows that fatigue is partly driven by cognitive biases, such as the self-as-fatigued identity bias, which may be corrected with computer-based Cognitive Bias Modification (CBM) techniques. Effectiveness of CBM has been demonstrated in a variety of domains, but is innovative for fatigue treatment in patients.

The aim of the IVY project is the intervention design of a (preventive) CBM-training. The intervention is developed in a co-creation approach with patients and various breast cancer health professionals. Currently, the new application is tested in a proof of concept design with patients undergoing  neo-adjuvant treatment and compare the primary and secondary outcome measures in a group that used the IVY app and a group of patients without access to IVY. In addition, a qualitative study explores the experiences using IVY and will identify essential aspects for the further development of the eHealth intervention and the keys for implementation in daily oncological practice.


Ziekenhuis Groep Twente, BVN



Contact person(s) in the SMHA lab:

Christina Bode, Marcel Pieterse