Elisabetta Rossi

Biography

Name: Elisabetta Rossi
Date of birth: 25 March 1975
Place of birth: Camposampiero (PD)
Academic position: Technician - DOSS University of Padova Institutional authorized official- prof. Zaccaria
Bachelor’s degree: Biological Science at the University of Padova, with marks 102/110 cum laude (2001)
Postgraduate studies: Clinical Pathology at the Medical School of the University of Padova, with marks 70/70 cum laude (2006)

Professional positions:

Technician at the at Oncology Section of the DOSS-University of Padova (since 2002).

Scientific activity:

13 publications in peer-reviewed journals; h-index 10

Research interests:

1. Physiology and pathology of the immune system;
2. Immunologic alterations during HIV infection;
3. Predictive value and biologic significance of Circulating Tumor Cells (CTC) in solid tumors.

Visiting fellowships:

2012: LLP-LifelongLearningProgramme Erasmus - Staff Training at the University of Twente (NL) - Department of Medical Cell Biophysics, headed prof. Leon WMM Terstappen

Grants

• 2004-2006: She has collaborated in the study " B cell deregulation during HIV infection: role of the HIV-1 matrix protein p17" (ISS–AIDS Project: # 40G.60, PI Rita Zamarchi).
• 2008-today: She collaborates in the Project Ricerca Sanitaria Finalizzata 2008 conducted at IOV-IRCCS of Padova (PI prof. A. Amadori), entitled " Predictive value and biologic significance of circulating tumour cells (CTC) in solid tumors".
• 2009-today: She collaborates in the Task 4 ("Characterization of circulating tumor cells in breast and ovary cancer ") of the "Progetto Oncologico di Medicina Molecolare: i tumori femminili" conducted at IOV-IRCCS of Padova (PI prof. P. Zanovello).
• 2009-today: She collaborates in the Project "construction of regulatory networks of cancer by integrating gene expression, alternative splicing and microRNA expression data" (PI prof. D.Nitti DOSS Padova), funded by AIRC.
• 2010-today: She collaborates in the Task 2 ("Evaluation of the CTC", coordinator Rita Zamarchi, IOV-IRCCS of Padova) of the Project " Metformin plus chemotherapy in advanced breast cancer: prognostic and predictive tools" (PI A. Gennari, IST Genova), funded by AIRC.
• 2011-today: She collaborates in the study " Predictive value of Circulating Melanoma Cells (CMC) in anti-BRAF treated Metastatic Melanoma" (coordinator Rita Zamarchi, IOV-IRCCS of Padova) of the ACC (Alleanza Contro il Cancro)/Project 3 (PI P. Zanovello, University od Padova).
• 2012-today: She collaborates in the:
  - Specific Programme “Cooperation” – Theme "Health"
  - Call identifier: FP7-HEALTH-2012-INNOVATION-1
  - Proposal No: 305341-2
  - Acronym: CTCtrap
• 2012-today: She coordinates as PI the study: Individualized treatment of patients with advanced NSCLC: potential application for circulating Tumor Cells (CTC) molecular and phenotypical profiling
  - BANDO PROGETTI DI RICERCA
  - GIOVANI RICERCATORI - RICERCA FINALIZZATA 2010
  - Project Code: GR-2010-2303193

Publications

1. Amadori A, Rossi E, Zamarchi R, Carli P, Pastorelli D, Jirillo A: Circulating and Disseminated Tumor Cells in the Clinical Management of Breast Cancer Patients: Unanswered Questions, Oncology 2009, 76:375-386
2. Antonello J, Rossi E, Basso U, Facchinetti A, Zagonel V, Swennenhuis JF, Terstappen LW, Amadori A, Zamarchi R: FEASIBILITY OF GENETIC ABERRATIONS ANALYSIS IN THE CIRCULATING TUMOR CELLS (CTCS), Annals of Oncology 2012, 23:91-91
3. Basso U, Rossi E, Indraccolo S, Barile C, Sava T, Aieta M, Brunello A, Jirillo A, Amadori A, Zamarchi R: Do circulating tumor cells (CTCs) correlate with response to first-line sunitinib in metastatic renal carcinoma?, Ejc Supplements 2009, 7:428-428
4. Ciminale V, Silic-Benussi M, D'Agostino DM, Cavallari I, Zorzan T, Rosato A, Willems L, Lairmore MD, Chieco-Bianchi L, Rossi E: Impact of the HTLV-1 p13II protein on cell growth and tumorigenesis, Aids Research and Human Retroviruses 2003, 19:S22-S22
5. Colombrino E, Rossi E, Ballon G, Terrin L, Indraccolo S, Chieco-Bianchi L, De Rossi A: Human immunodeficiency virus type 1 Tat protein modulates cell cycle and apoptosis in Epstein-Barr virus-immortalized B cells, Experimental Cell Research 2004, 295:539-548
6. Conteduca V, Zamarchi R, Rossi E, Condelli V, Troiani L, Aieta M: Circulating tumor cells: utopia or reality?, Future Oncology 2013, 9:1337-1352
7. Favaro E, Nardo G, Persano L, Masiero M, Moserle L, Zamarchi R, Rossi E, Esposito G, Plebani M, Sattler U, Mann T, Mueller-Klieser W, Ciminale V, Amadori A, Indraccolo S: Hypoxia inducible factor-1 alpha inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death, American Journal of Pathology 2008, 173:1186-1201
8. Jirillo A, Carli P, Zamarchi R, Rossi E, Amadori A: CIRCULATING TUMOR CELLS IN BREAST CANCER, Annals of Oncology 2008, 19:253-253
9. Mandruzzato S, Rossi E, Bernardi F, Tosello V, Macino B, Basso G, Chiarion-Sileni V, Rossi CR, Montesco C, Zanovello P: Large and dissimilar repertoire of Melan-A/MART-1-specific CTL in metastatic lesions and blood of a melanoma patient, Journal of Immunology 2002, 169:4017-4024
10. Moserle L, Indraccolo S, Ghisi M, Frasson C, Fortunato E, Canevari S, Miotti S, Tosello V, Zamarchi R, Corradin A, Minuzzo S, Rossi E, Basso G, Amadori A: The side population of ovarian cancer cells is a primary target of IFN-alpha antitumor effects, Cancer Research 2008, 68:5658-5668
11. Nardo G, Favaro E, Curtarello M, Moserle L, Zulato E, Persano L, Rossi E, Esposito G, Crescenzi M, Casanovas O, Sattler U, Mueller-Klieser W, Biesalski B, Thews O, Canese R, Iorio E, Zanovello P, Amadori A, Indraccolo S: Glycolytic Phenotype and AMP Kinase Modify the Pathologic Response of Tumor Xenografts to VEGF Neutralization, Cancer Research 2011, 71:4214-4225
12. Pizzini S, Bisognin A, Mandruzzato S, Biasiolo M, Facciolli A, Perilli L, Rossi E, Esposito G, Rugge M, Pilati P, Mocellin S, Nitti D, Bortoluzzi S, Zanovello P: Impact of microRNAs on regulatory networks and pathways in human colorectal carcinogenesis and development of metastasis, BMC Genomics 2013, 14:
13. Rossi E, Basso U, Celadin R, Zilio F, Pucciarelli S, Aieta M, Barile C, Sava T, Bonciarelli G, Tumolo S, Ghiotto C, Magro C, Jirillo A, Indraccolo S, Amadori A, Zamarchi R: M30 Neoepitope Expression in Epithelial Cancer: Quantification of Apoptosis in Circulating Tumor Cells by CellSearch Analysis, Clinical Cancer Research 2010, 16:5233-5243
14. Rossi E, Facchinetti A, Grassi A, Rossi CR, Stragliotto S, Pigozzo J, Chiarion-Sileni V, Amadori A, Zanovello P, Zamarchi R: Potential applications of circulating melanoma cells (CMCs) expressing gamma-H2AX, Journal of Clinical Oncology 2013, 31:
15. Rossi E, Facchinetti A, Zamarchi R: Customizing CellSearch platform, Cytometry Part A 2013, 83A:595-598
16. Rossi E, Fassan M, Aieta M, Zilio F, Celadin R, Borin M, Grassi A, Troiani L, Basso U, Barile C, Sava T, Lanza C, Miatello L, Jirillo A, Rugge M, Indraccolo S, Cristofanilli M, Amadori A, Zamarchi R: Dynamic changes of live/apoptotic circulating tumour cells as predictive marker of response to Sunitinib in metastatic renal cancer, British Journal of Cancer 2012, 107:1286-1294
17. Silic-Benussi M, Cavallari L, Zorzan T, Rossi E, Hiraragi H, Rosato A, Horie K, Saggioro D, Lairmore MD, Willems L, Chieco-Bianchi L, D'Agostino DM, Ciminale V: Suppression of tumor growth and cell proliferation by p13(II), a mitochondrial protein of human T cell leukemia virus type 1, Proc Natl Acad Sci U S A 2004, 101:6629-6634
18. Tramentozzi E, Zamarchi R, Pagetta A, Brunati AM, Rossi E, Tibaldi E, Finotti P: Effects of glucose-regulated protein94 (Grp94) on Ig secretion from human blood mononuclear cells, Cell Stress & Chaperones 2011, 16:329-338
19. Tramentozzi E, Zamarchi R, Rossi E, Pagetta A, Frigo G, Finotti P: Inhibition of immunoglobulin secretion from peripheral blood mononuclear cells by glucose-regulated protein94 (Grp94) in allergic subjects, Molecular and Cellular Biochemistry 2012, 365:47-52
20. Vincenzi B, Rossi E, Zoccoli A, Iuliani M, Pantano F, Frezza AM, Silletta M, Tonini G, Zamarchi R, Santini D: CIRCULATING TUMOR CELLS IN SOFT TISSUE SARCOMAS PATIENTS, Annals of Oncology 2012, 23:489-489
21. Zovato S, Opocher G, Rossi E, Indraccolo S, Amadori A, Pastorelli D, Lombardi G, Anglani M, Zamarchi R: Predictive value and biologic significance of circulating tumor cells (CTC) in sporadic and von hippel lindau (VHL) renal cancer, Ejc Supplements 2009, 7:436-437
22. Zovato S, Rossi E, Indraccolo S, Anglani M, Pastorelli D, Lombardi G, Opocher G, Amadori A, Zamarchi R: PREDICTIVE VALUE AND BIOLOGIC SIGNIFICANCE OF CIRCULATING TUMOR CELLS (CTC) IN SPORADIC AND VON HIPPEL LINDAU (VHL) RENAL CANCER, Annals of Oncology 2009, 20: