Scientific Output


Aasheim HC , Terstappen LWMM, T Logtenberg. Regulated expression of the Eph-Related Receptor Tyrosine Kinase Hek11 in early human B lymphopoiesis. BLOOD 90: 3613-3622 (1997).


Ho AD, Young D, Maruyama M, Law P, Corringham ET, Mason JR, Oldham F, Mills B, Terstappen L, Lane TA. Mobilization and purification of CD34+ cells from normal donors regimens with G-CSF, GM-CSF, or a combination of both. Bone Marrow Transplantation 17: S34-37, (1996).


Gahn B, Haase D, Unterhalt M, Drescher M, Schoch C, Fonatsch C, Terstappen LWMM, Hiddeman W, Buchner Th, Bennett JM, Wormann B. De novo AML with dysplastic hematopoeisis: cytogenetic and prognostic significance. Leukemia 10: 946-951 (1996).


Olweus J, Terstappen LWMM. Lund-Johansen F, Expression and function of receptors for stem cell factor and erythropoietin during lineage commitment of human hematopoietic progenitor cells. BLOOD 88: 1594-1607 (1996).


Ho AD, Young D, Maruyama M, Corringham ET, Mason JR, Thompson P, Grenier K, Law P,Terstappen L, Lane TA. Pluripotent and lineage-committed CD34+ subsets mobilized by G-CSF, GM-CSF,versus a combination of both. Exp Hematology. 24: 1460-1468 (1996).


Civin C I, Almeida-Porada G, Lee MJ, Terstappen LWMM, Zanjani ED. Sustained, retransplantable, multilineage engraftment of highly purified adult human bone marrow stem cells in vivo. BLOOD 88: 4102-4109 (1996).


Waller EK, Olweus J, Lund-Johansen F, Huang S, Nguyen M, Guo GR, Terstappen LWMM. The “common stem cell” hypothesis reevaluated: Human fetal bone marrow contains separate populations of hematopoietic and stromal progenitors. BLOOD 85:2422-2435, (1995).


Prince GM, Nguyen M, Brodsky RA, Lazarus HM, Terstappen LWMM, Medof ME. Peripheral blood harvest of CD34+ hematopoietic precursors in paroxysmal nocturnal hemoglobinuria. BLOOD 85: 3381-3386, (1995).


Waller EK, Huang S, Terstappen LWMM. Changes in growth properties of CD34+, CD38- bone marrow progenitors during fetal development. BLOOD 86:710-718, (1995).


Lane TA, Law P, Maruyama M, Young D, Butgess J, Mullen M, Mealiffe M, Terstappen LWMM, Hardwick A, Moubayed M, Oldham F, Corringham RET, Ho AD. Harvesting and enrichment of hematopoietic stem cells mobilized into the peripheral blood of normal donors by G-CSF or GM-CSF. BLOOD 85: 275-282 (1995).


Olweus J, Lund-Johansen F, Terstappen LWMM. CD64 / FcgR1 is a granulo-monocytic lineage marker on CD34+ hematopoietic progenitor cells. BLOOD 85: 2402-2413, (1995).


de Kruif J, Terstappen LWMM, Boel E, T Logtenberg. Rapid selection of cell subpopulations-specific human monoclonal antibody fragments from a synthetic phage antibody library. PNAS 92: 3938-3942 (1995).


Moore T, Huang S, Terstappen LWMM, Bennett M, Kumar V. Expression of CD43 on murine and human pluripotent hematopoietic stem cells. J. Immunology. 153: 4978-4987 (1994).


Huang S, Terstappen LWMM. Lymphoid and myeloid differentiation of single human CD34+, HLA-DR+, CD38- hematopoietic stem cells.BLOOD 83: 1515-1526 (1994).


Lund-Johansen F, Terstappen LWMM. Differential expression of cell adhesion molecules during granulocyte maturation. J.Leuk. Biol.54:47-55 (1993).


Terstappen LWMM, Gandour D, Huang S, Lund -Johansen F, Manion K, Mickaels R, Nguyen M, Olweus J, Toepker S: Assessment of hematopoietic cell differentiation by multidimensional flow cytometry. J. Hematotherapy. 2: 431-477 (1993).


Picker LJ, Treer JR, Nguyen M,Terstappen LWMM, Hogg N, Yednock T. Coordinate Expression of b1 and b2 Integrin "Activation" Epitopes During T Cell Responses in Secondary Lymphoid Tissue. Eur J Immunol. 23: 2751-2757 (1993).


Wormann B, Safford M, Konemann S, Buchner T, Hiddemann W, Terstappen LW. Detection of aberrant antigen expression in acute myeloid leukemia by multiparameter flow cytometry. Recent Results Cancer Res 131:185-96 (1993).


Terstappen LWMM, Huang S: Analysis of bone marrow stem cells. Blood Cells, 20: 45-63 (1994).


Chia Huei Chen, Wendy Lin, Shou Shye, Ruth Kibler, Kathy Grenier, Diether Recktenwald, Leon WMM Terstappen. Automated enumeration of CD34+ cells in peripheral blood and bone marrow. J of Hematotherapy 3: 3-13 (1994).


Terstappen LWMM, Lund-Johansen F. Hematopoietic progenitors in fetal and adult tissue. Blood Cells 20: 392-396 (1994).


Olweus J, Lund-Johansen F, Terstappen LWMM. Cell surface antigen expression during early hematopoietic cell differentiation in adult and fetal bone marrow. Immunomethods 5: 179-188 (1994).


Huang S, Terstappen LWMM Formation of both hematopoietic microenvironment and hematopoietic stem cells from single sorted human bone marrow stem cells. Nature, 360: 745-749 (1992). Correction: Nature, 368: 664 (1994).


Wörmann B , Safford M, Könemann S, Zurlutter K, Piechotka K, Schreiber K, Loken MR, Sauerland C, Büchner Th, Hiddemann W, Terstappen LWMM.Prospective study on the clinical relevance of residual disease in patients with acute myeloid leukemia in complete remission. Hematology and Blood Transfusion 36:675-680, (1994)


Picker LJ, Treer JR, Ferguson-Darnell B, Collins P, Buck D, Terstappen LWMM. Control of lymphocyte circulation in man: I Differential regulation of the peripheral lymph node homing receptor L-Selectin on T cells during the virgin to memory cell transition. J Immunology, 150: 1105-1121 (1993).


Picker LJ, Treer JR, Ferguson-Darnell B, Collins P, Bergstresser PR, Terstappen LWMM. Control of lymphocyte circulation in man: II. Differential regulation of the cutaneous lymphocyte-associated antigen (CLA), a tissue-selective homing receptor for skin-homing T cells. J Immunology, 150: 1122-1136 (1993).


Terstappen LWMM, Nguyen M, Huang S, Lazerus H, Medof E. Defective and normal hematopoietic stem cells in paroxysmal nocturnal hemoglobinuria. Br J Haematol, 84, 504-514 (1993).


Verwer B, Terstappen LWMM. Automatic lineage assignment of acute leukemias by flow cytometry. Cytometry 14: 862-875 (1993).


Reading C, Huh Y, Estey E, Claxton DF, Sanchez G, Terstappen L, O’Brien M, Baron S, Deisseroth A. Aberrant surface phenotype expression in acute myelogenous leukemia. BLOOD 81: 3083-3090 (1993).


Collins RH, Anastasi J, Terstappen LWMM, Nikaein A, Fay JW, Klintmalm G. Donor-derived long-term multilineage hematopoiesis in a liver transplant recipient. N. Engl.J. Med. 328: 762-765 (1993).


Terstappen LWMM, Loken MR. Leukocyte differential counting. Flowcytometry in hematology. Laereum O.D., Bjerknes R.(eds) Academic Press, London, 95-107 (1992).


Terstappen LWMM, Huang S, Picker LJ. Flow cytometric assessment of human T-cell differentiation in thymus an bone marrow. BLOOD 79; 666-677 (1992).


Terstappen LWMM, Safford M, Unterhalt M, Könemann S, Zurlutter K, Piechotka K, Drescher M, Aul C, Büchner Th, Hiddemann W, Wörmann B. Flow cytometric characterization of acute myeloid leukemias. IV. Comparison of the differentiation pathway of normal hematopoietic progenitor cells. Leukemia 6: 993-1001 (1992)


Terstappen LWMM, Levin J. Bone marrow differential counts obtained by multidimensional flow cytometry. Blood Cells 18:311-330 (1992).


Terstappen LWMM, Buescher S, Nguyen M, Reading C. Differentiation and maturation of growth factor expanded early human hematopoeitic progenitors assessed by multidimensional flow cytometry. Leukemia 6: 1001-1011 (1992).


Terstappen LWMM, Nguyen M, Lazerus H, Medof E. Expression of DAF (CD55) and CD59 antigens during normal hematopoeitic cell differentiation. J Leuk Biol, 52: 652-660 (1992).


Loken MR, Civin CI, Shah VO, MJ Fackler, Segers-Nolten I, Safford M, Terstappen LWMM. Flow cytometric characterization of erythroid, lymphoid and monomyeloid lineages in normal human bone marrow. Flowcytometry in hematology. Laereum O.D., Bjerknes R. (eds) Academic Press, London, 95-107 (1992).


Terstappen LWMM, Könemann S, Safford M, Loken MR, Zurlutter K, Büchner Th, Hiddemann W, Wörmann B. Flow cytometric characterization of acute myeloid leukemias. I. Significance of light scattering properties. Leukemia 5; 315-321 (1991).


Terstappen LWMM, Huang S, M Safford, Lansdorp PM,Loken MR. Sequential generations of hematopoietic colonies derived from single non lineage committed progenitor cells. BLOOD 77; 1218-1227 (1991).


Terstappen LWMM, Johnson D, Mickaels RA, Chen J, Olds G, Hawkins JT, Loken MR, Levin J. Multidimensional flow cytometric blood cell differentiation without erythrocyte lysis. Blood Cells 17: 585-602 (1991).


Terstappen LWMM, Safford M, Könemann S, Loken MR, Zurlutter K, Büchner Th, Hiddemann W, Wörmann B. Flow cytometric characterization of acute myeloid leukemias. II. Phenotypic heterogeneity at presentation. Leukemia 5; 757-767 (1991).


Lansdorp PM, Smith C, M Safford, Terstappen LWMM, Thomas TE. Single laser three color immunofluorescence staining procedures based on energy transfer between phycoerythrin and cyanine 5. Cytometry 12; 723-730 (1991).


Terstappen LWMM, Mickaels R, Dost R, Loken MR. Increased light scattering resolution facilitates multidimensional flow cytometric analysis. Cytometry 11; 506-512 (1990).


Terstappen LWMM, Loken MR. Myeloid cell differentiation in normal bone marrow and acute myeloid leukemia assessed by multi-dimensional flow cytometry. Analytical Cellular Pathology 2; 229-240 (1990).


Terstappen LWMM, Johnsen S, Segers-Nolten I, Loken MR. Identification and characterization of normal human plasma cells by high resolution flow cytometry. BLOOD 76; 1739-1747 (1990).


Terstappen LWMM, Safford M, Loken MR. Flow cytometric analysis of human bone marrow III. Neutrophil development. Leukemia 4; 657-663 (1990).


Picker LJ, Terstappen LWMM, Rott LS, Streeter PR, Stein H, Butcher EC. Differential expression of homing-associated adhesion molecules by T-Cell subsets in man. J Immunology 145; 3247-3255 (1990).


Terstappen LWMM, Z Hollander,Meiners H, Loken MR. Quantitative comparison of myeloid antigens on five lineages of mature peripheral blood cells. J of Leukocyte Biology 48: 138-148 (1990).


Terstappen LWMM, de Grooth BG, Nolten GMJ, Greve J. Cytotoxic lymphocytes in B-cell chronic lymphocytic leukemia. A flow cytometric study of peripheral blood and bone marrow. Blut 60:81-87 (1990).


Terstappen LWMM, Meiners H, Loken MR. A rapid sample preparation technique for flow cytometric analysis of immunofluorescence allowing absolute enumeration of cell subpopulations. J Immunol Methods 123; 103-112 (1989).


Terstappen LWMM, de Grooth BG, Visscher K, van Kouterik FA, Greve J. Four-Parameter White Blood Cell Differential Counting Based on Light Scattering Measurements. Cytometry 9: 39-43 (1988).


Terstappen LWMM, de Grooth BG, van Berkel W,ten Napel CHH, Greve J. Application of Orthogonal Light Scattering for Routine Screening of Lymphocyte Samples. Cytometry 9: 220-225 (1988).


Terstappen LWMM. de Grooth BG, van Berkel W,ten Napel CHH, Greve J. Flow Cytometric Characterization of Chronic Lymphocyte Leukemias using Orthogonal Light Scattering and Quantitative Immunofluorescence. Blut 56: 201-208 (1988).


Terstappen LWMM , de Grooth BG, van Berkel W,ten Napel CHH, Greve J. Abnormal distribution of CD8 subpopulation in B- Chronic Lymphocytic Leukemia identified by Flow Cytometry. Leukemia Research 12: 551-557 (1988).


Terstappen LWMM , de Grooth BG, van Berkel W,ten Napel CHH, Greve J. The Effects of Splenic Irradiation on Lymphocyte Subpopulations in B-Chronic Lymphocytic Leukemia. Eur J of Haematol 41: 496-505 (1988).


Terstappen LWMM, Shah VO., Conrad MP. ,Recktenwald, D., LokenMR. Discriminating between Damaged and Intact Cells in Fixed Flow Cytometric Samples. Cytometry 9: 477-484 (1988).


Terstappen LWMM, Loken MR. 5 Dimensional Flow Cytometry as a New Approach for Blood and Bone Marrow Differentials. Cytometry 9: 548-556 (1988).


Terstappen LWMM. Flow Cytometric Characterization of White Blood Cells of Healthy Donors and Patients with Lymphocytic Diseases. ISBN 90-9002197-3, June 1988 (Thesis).


Terstappen LWMM, de Grooth BG, Nolten GMJ, ten Napel CHH, van Berkel W, GreveJ. Physical discrimination between human T lymphocyte subpopulations by means of Light Scattering, revealing two populations of T8-positive cells. Cytometry 7: 178-183 (1986).


Terstappen LWMM, de Grooth BG, ten Napel CHH, van Berkel W, Greve J.Discrimination of Human Cytotoxic Lymphocytes from Regulatory and B-lymphocytes by Orthogonal Light Scattering. J Immunol Methods 95: 211-216 (1986).


de Grooth BG, Terstappen LWMM, Puppels GJ, Greve J. Light-Scattering Polarization Measurements as a New Parameter in Flow Cytometry. Cytometry 8: 539-544 (1987).


Terstappen LWMM, de Grooth BG, Nolten GMJ, ten Napel CHH, van Berkel W, GreveJ. Flow Cytometric determination of Circulating Immune Complexes with the Indirect Granulocyte Phagocytosis Test. Cytometry 6: 316-320 (1985).


Terstappen LWMM , Arends RPJH, ten Napel CHH. Hereditair Lymfoedeem, een vaak miskende vorm van chronisch oedeem; Klinisch onderzoek bij 2 families met de ziekte van Meige.Ned. Tijdschrift. Geneesk. 129: 208-212 (1985).