Scientific Output


Miller MC, Gerald V Doyle GV, Leon WMM Terstappen LWMM. Significance of Circulating Tumor Cells detected by the CellSearch® System in Patients with Metastatic Breast Colorectal and Prostate Cancer. J Oncology Vol 2010, Article ID 617421, 2010.


Li X, Breukers C, Ymeti A, Pattanapanyasat K, Sukapirom K, Terstappen LWMM, Greve J. Clinical Evaluation of a Simple Image Cytometer for CD4 Enumeration on HIV Infected Patients. Cytometry Part B 78B, 31-36, 2010.


Tol J, Koopman, Miller MC, Tibbe A, Cats A, Creemers GJM, Vos AH, Nagtegaal ID, Terstappen LWMM, Punt CJA. Circulating tumour cells early predict progression-free and overall survival in advanced colorectal cancer patients treated with chemotherapy and targeted agents. Annals of Oncology 21: 1006-1012, 2010.


Reid AHM, Attard G, Danila DC, Oommen NB, Olmos D, Fong PC, Molife LR, Hunt J, Messiou C, Parker C, Dearnaley D, Swennenhuis JF, Terstappen LW, Lee G, Kheoh T, Molina A, Ryan C, Small E, Scher HI, de Bono JS. Significant and sustained anti-tumor activity in post-docetaxel castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate. JCO 28,1489-1495, 2010.


Coumans F, Doggen CJM, Attard G, de Bono JS, Terstappen LWMM. All circulating EpCAM+CD45-CK+ but not EpCAM+CD45+CK+ objects predict overall survival in castration-resistant prostate cancer. Ann Oncol 21, 1851-1857, 2010.



Strijbos MH, Gratama JW, Schmitz PIM, Rao C, Onstenk W, Doyle GV, Miller C, de Wit R, Terstappen LWMM, Sleijfer S. Circulating Endothelial Cells, Circulating Tumour Cells, Tissue Factor, Endothelin-1 and Overall Survival In Prostate Cancer Patients Treated With Docetaxel. European Journal Of Cancer, 46: 2027–2035, 2010.


Simkens LHJ, Tol J, Terstappen LWMM, Teerenstra S, Punt CJA, Nagtegaal ID. The predictive and prognostic value of circulating endothelial cells in advanced colorectal cancer patients receiving first-line chemotherapy and bevacizumab. Ann Oncol, 21: 2477-2448, 2010.


Wu, C.C., Reinhoudt, D.R., Otto, C., Velders, A., Subramaniam, V., (2010) Protein Immobilization on Ni(II) Ion Patterns Prepared by Microcontact Printing and Dip-pen Nanolithography. ACSNano Vol. 4(2), 1083-1091.


Pully, V.V., Lenferink, A. Subramaniam, V., Blitterswijk, C. van., Otto, C. (2010) Microbioreactors for Raman of Stromal Cell Differentiation. Anal. Chem. 82, p. 1844 – 1850.


Pully, V.V. Lenferink, A., Otto, C., (2010) Hybrid Rayleigh-, Raman and TPE fluorescence spectral confocal microscopy of living cells. J. of Raman Spectroscopy 41(6), p. 599-608.


Rayavarapu, R.G., Petersen, W., Hartsuiker, L., Chin, P., Janssen, H., van Leeuwen, F.W.B., Otto, C., Manohar, S., van Leeuwen, T.G. (2010) In vitro toxicity studies of polymer-coated gold nanorods, Nanotechnology 21(14) 145101.


Escalante, M., Lenferink, A., Zhao, Y., Tas, N., Huskens, J., Hunter, C.N., Subramaniam, V., Otto, C. (2010) Long-range energy propagation in Nanometer arrays of light harvesting antenna complexes, Nano Letters 10, 1450-1457.


Pully, V.V. Lenferink, A., Otto, C., (2010) Raman-Fluorescence hybrid microspectroscopy of cell nuclei. Vibrational Spectroscopy 53, 12-18.


Orsel, K., Garbacik, E.T, Jurna, M., Korterik, J.P., Otto, C., Herek, J.L., Offerhaus, H.L. (2010) Heterodyne Interferometric Polarization Coherent anti-Stokes Raman scattering (HIP-CARS) spectroscopy, J. of Raman Spectroscopy 40, 1-4, doi: 10.1002/jrs.2621.


Murade, C.U., Subramaniam, V., Otto, C., Bennink, M.L., (2010) Force spectroscopy and fluorescent microscopy of dsDNA-YOYO-1 complexes: Implications for the structure of dsDNA in the overstretching region. Nucleic Acids Research, 38(10), 3423 - 3431


Tucker, J.D., Siebert, C.A., Escalante, M., Adams, P.G., Olsen, J.D., Otto, C., Stokes, D.L., Hunter, C.N. (2010) Membrane invaginations in Rhodobacter Sphaeroides is initiated at curved regions of the cytoplasmic membrane, then forms budded and fully detached spherical Vesicles. Molecular Microbiology 76(4), 833-847.


J.S. Lee, W. Zhou, F. Meng, D. Zhang, C. Otto, and J. Feijen. (2010) Thermosensitive hydrogel-containing polymersomes for controlled drug delivery. Journal of Controlled release, 146, 400-408. doi: 10.1016/j.corel.2010.06.002.


Jurna, M. Garbacik, E. Korterik, J., Herek, J., Otto, C., Offerhaus, H.L., (2010) Visualizing resonances in the complex plane with vibrational phase contrast CARS, Anal. Chem. 82(18), 7656 – 7659.


Pol, E. van der, Hoekstra, A.G., Sturk, A., Otto, C., Leeuwen, T.G. van, Nieuwland, R., (2010) Optical and Non-optical methods for detection and characterization of microparticles and exosomes. Journal of Thrombosis and Haemostasis. 8, 2596-2607.


Hartsuiker, L., Zeijen, N.J.L., Terstappen, L.W.M.M., Otto, C. (2010) A comparison of breast cancer tumor cells with varying expression of the Her2/neu receptor by Raman microspectroscopic imaging, Analyst, 135, 3220-3226, DOI:10.1039/C0AN00524J.


Jin, M., Pully, V.V., Otto, C., van de Berg, A., Carlen, E.T. (2010) High density periodic arrays of ultra-precise sub-wavelength Nanopyramids for surface enhanced Raman scattering, J. Phys. Chem. C 114(50), 21953-21959.