Clinical Neurophysiology

The research of this group is performed at the interface of neuroscience and neurophysiology. Strongly driven by clinical needs, we focus on central nervous system disorders, aiming to develop improved diagnostics and guide novel treatments for clinical neurology.

We have various research themes, that are strongly interrelated, and where the EEG is an important measurement tool. There is strong collaboration with various other groups at the University of Twente and the department of neurology and clinical neurophysiology of the Medisch Spectrum Twente (MST).

Most group members and PhD students also work part-time in a clinical setting, which strongly assists in the translation of the research to the clinical reality. In addition, in most research projects clinical data from neurological patients is involved, e.g. EEG measurements or recordings obtained in the Intensive Care Unit of the MST.


Specific topics are epilepsy, ischaemia/stroke, neuromonitoring and neuromodulation.

In the first three topics, a common element is the use of the EEG as a diagnostic tool, assisted by computational modeling and the use of transcranial magnetic stimulation.

Neuromodulation focuses on applications for chronic pain, using spinal cord stimulation, tinnitus, and epilepsy (vagus nerve stimulation).