Rest tremor is the most common and easily recognized symptom of Parkinson’s disease (PD), but still many questions exist with regard to its origin and the neuronal pathways involved. Less well recognized in PD, but often more disabling is the occurrence of action tremor, which is any tremor that is produced during voluntary muscle contraction. In general, deep brain stimulation in the subthalamic nucleus (STN-DBS) operates with different magnitudes of clinical efficacy based on the specific motor deficit, but its effect may also be task-specific. These differential effects of DBS on PD motor symptoms are hardly explained in literature. We have explored if rest and action tremor react in a differential way to clinically effective and less effective DBS using quantitative tremor analysis methods.
Wednesday 12 November 2014, 16:30 - 17:30 h
Building Carré - room CR 3.718