From Neural Circuit Behaviour to Human Sensory-Motor Function

micro meso macro

Within this theme we investigate how human function arises from the neural system and how impaired or lost functionality can be restored by neural sensing or modulation techniques. Sensory, nociceptive and motor function are observed using psychophysical methods, movement sensing and neurophysiological recordings. Stimulation methods are optimized for identification, control or modulation of neural mechanisms underlying human functions of interest. This theme advances our understanding of the human functions under normal as well as pathological conditions and provide starting points for the development of clinically applicable diagnostic, therapeutic and rehabilitation methods.

From Neural Circuit Behaviour to Human Sensory-Motor Function

Softpro logo


The main objective of the SoftPro project is to fulfil Henry Ford’s vision to assist people with upper limb amputations or motor disabilities providing them with robotics-enabled aids. To do so, we need not only to produce new technology and better performing devices; we also need to make the technology accessible to and affordable for real people with real needs. ... read more

Human function level

NeuroCimt / Counteract

Sensing and action to counteract maladaptation in motor performance in patients with neurological disorders: transfer from clinic to daily-life. ... read more

ENHANCE overview

eNHANCE – intelligent multimodal interface to improve autonomy of upper-extremity motor function disabled people

The objective of the eNHANCE project is to develop, demonstrate and initiate exploitation of new concepts to enhance and train upper extremity motor function in people with physical disabilities during daily-life. The new concepts entail an intelligent and natural multimodal adaptive interface that features high-performance natural intention detection using low-cost high data-rate eyetracking and supporting sensor modalities, and intelligently-controlled dexterous arm and hand support. The intelligent control ensures that the user is enabled to perform the intended motor tasks with minimal support, while effectively motivating the user in a personalized and context-aware manner to maximize his/her contribution to ensure maximal therapeutic effect. ... read more

Deep Brain Stimulation in Parkinson's Disease - Towards an intelligent form of neural modulation

The “Deep Brain Stimulation in Parkinson's Disease - Towards an intelligent form of neural modulation” project (also known as the iDBS project) is funded by TWIN, a Dutch initiative to support research on neural modulation. The collaborating partners within the project are University of Twente (UT) and the Academic medical Center in Amsterdam (AMC). ... read more

NeuroSIPE: The movement diagnostic system

A diagnostic system will be developed to capture abnormal brain activations in movement disorders patients, combining functional MRI, measures of muscle activity, video tracking devices and ... read more