MESA+ University of Twente
The BIOS Lab-on-a-chip group


Electrochemical sensors and sensor systems

This research area covers the development of knowledge and expertise of the electrode-liquid interface and its application in electrochemical micro-and nanodevices. The three basic detection principles are studied: potentiometry, amperometry and conductometry. Besides developing electrochemical sensors, the integration into lab-on-a-chip systems is implemented using cleanroom microfabrication. This opens up new operational principles such as redox cycling and the use of ultra-micro electrodes. In addition, integration of electrochemical cells in a Lab-on-a-chip enables the conversion of electro-active species.

Application of these electrochemical sensors and systems are in the field of health care, life sciences as well as in the field of environment and sustainability.

Research projects


On-chip spermatozoa testing for artificial insemination


Liquid Chromatography/on-chip-electrochemistry/mass-spectrometry in (bio) analytical chemistry, drug metabolism and proteomics


Cotinine detection


Lactate monitoring for intensive care and endurance sports


Monitoring of the catalytic conversion process on single catalyst particles by impedance spectroscopy


Spatial control of pH in a Lab-on-a-Chip


pH sensing in microvolumes


NO, O2 and pH sensing for vascular engineering

SEM photo of a parylene-covered anopore membrane after pyrolysis and activation, used for novel super capacitor electrodes.

Cyclic voltammograms at 50 mV/s for super capacitor characterization.

For more information contact: Wouter Olthuis








+31 (0)53 489 26 88




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