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curriculum vitae

Jeroen Cornelissen
Name: Prof. dr. Jeroen J.L.M. Cornelissen
Room: Carre: 4.225
Phone: +31 53489 4380
Fax: +31 53489 4645
Secret.:+31 53489 2980

Jeroen Cornelissen is Professor in Biomolecular Nanotechnology at the University of Twente, Enschede, the Netherlands. He studied chemistry in The Netherlands with a minor in polymer chemistry carried out at the Eindhoven University of Technology with Prof. E.W. Meijer and a major in Supramolecular Chemistry and Catalysis at the University of Nijmegen with Prof. R.J.M. Nolte. He received his PhD (cum laude) from the latter university in 2001 for research carried out under the supervision of Prof. R.J.M. Nolte. After post-doctoral work at the IBM Almaden Research Center in San Jose, U.S.A. he returned to Nijmegen, where he was appointed as an Assistant Professor until 2009. His current research interests are in well-defined polymer architectures, hybrid systems of synthetic macromolecules and biopolymers and the use of viruses as building blocks in functional materials


Name: Dr. J.J.L.M. Cornelissen
Born: August 12, 1972 in Veghel, The Netherlands
Nationality: Dutch
Marital status: Married, two children

Working Experience

  • 2009-present: Full Professor in Biomolecular Nanotechnology, MESA+ Institute, University of Twente, Enschede, the Netherlands
  • 2002-2009: Assistant Professor, Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen, the Netherlands
  • 2001-2002: Post-doctoral researcher, Advanced Organic Materials group IBM Almaden Research Center, San Jose, CA, U.S.A.
  • 1996-2001: PhD in Organic Chemistry / Polymer Chemistry, Katholieke Universiteit Nijmegen, Nijmegen, the Netherlands,
    Thesis: “Polymers and Block Copolymers of Isocyanopeptides – Towards Higher Structural Order in Macromolecular Systems”


  • Veni Innovative Research Grant NWO in 2002
  • 2002 IUPAC Prize for Young Chemists
  • 2002 SNS Bank Prijs
  • Vidi Innovative Research Grant NWO in 2005
  • Emerging Young Investigator in Materials Science, J. Mater. Sci. special issue (2007).
  • 2007 EURYI Award
  • Beijerinck Premium 2008 for Virology from the Royal Netherlands Academy for Arts and Sciences.


  • E. Schwartz, P. Bodis, M. Koepf, J.J.L.M. Cornelissen, A.E. Rowan, S. Woutersen, R.J.M. Nolte, Self-trapped vibrational states in synthetic B-sheet helices, Chemical communications, 2009, 31, 4675-4677 (2009).
  • E. Schwartz, M. Koepf, H., M. Espelt, V.J. Nebot-Carda, R. De Gelder, R.J.M. Nolte, J.J.L.M. Cornelissen, A.E. Rowan, Water soluble azido polyisocyanopeptides as functional beta-sheet mimics, Journal of Polymer Science Part A: Polymer Chemistry, 47, 16, 4150-4164 (2009).
  • A.J. Dirks, S.S. van Berkel, H.I.V. Amatdjais-Groenen, F.J.T. Rutjes, J.J.L.M. Cornelissen, R.J.M. Nolte, Synthesis and aggregation behavior of biohybrid amphiphiles composed of a tripeptidic head group and a polystyrene tail, Soft matter, 5, 8, 1692-1704 (2009).
  • A. de la Escosura, R.J.M. Nolte, J.J.L.M. Cornelissen, Viruses and protein cages as nanocontainers and nanoreactors, Journal of materials chemistry, 19, 16, 2274-2278 (2009).
  • I.C. Reynhout, J.J.L.M. Cornelissen, R.J.M. Nolte, Synthesis of Polymer−Biohybrids: From Small to Giant Surfactants, Accounts of chemical research, 42, 6, 681-692 (2009).
  • K.T. Kim, J.J.L.M. Cornelissen, R.J.M. Nolte, J.C.M. van Hest, A Polymersome Nanoreactor with Controllable Permeability Induced by Stimuli-Responsive Block Copolymers, Advanced materials, 21, 27, 2787-2791 (2009).
  • M. Nallani, R. Woestenenk, H.M. de Hoog, S.F.M. van Dongen, J. Boezeman, J.J.L.M. Cornelissen, R.J.M. Nolte, J.C.M. van Hest, Sorting Catalytically Active Polymersome Nanoreactors by Flow Cytometry, Small, 5, 10, 1138-1143 (2009).
  • E. Schwartz, V. Palermo, C.E. Finlayson, Y. Huang, M.B.J. Otten, A. Liscio, S. Trapani, I. González-Valls, P. Brocorens, J.J.L.M. Cornelissen, K. Peneva, K. Müllen, F.C. Spano, A. Yartsev, S. Westenhoff, R.H. Friend, D. Beljonne, R.J.M. Nolte, P. Samorì, A.E. Rowan, "Helter-Skelter-Like" Perylene Polyisocyanopeptides, Chemistry - A European Journal, 15, 11, 2536-2547 (2009).
  • C.E. Finlayson, R.H. Friend, M.B.J. Otten, E. Schwartz, J.J.L.M. Cornelissen, R.J.M. Nolte, A.E. Rowan, P. Samorì, V. Palermo, A. Liscio, K. Peneva, K. Müllen, S. Trapani, D. Beljonne, Electronic Transport Properties of Ensembles of Perylene-Substituted Poly-isocyanopeptide Arrays, Advanced Functional Materials, 18, 25, 3947-3955 (2008).
  • S.F.M. van Dongen, R.L.M. Teeuwen, M. Nallani, S.S. van Berkel, J.J.L.M. Cornelissen, R.J.M. Nolte and J.C. M. van Hest, Single-Step Azide Introduction in Proteins via an Aqueous Diazo Transfer, Bioconjugate chemistry, 20, 1, 20-23 (2009).
  • S.F.M. van Dongen, M. Nallani, J.J.L.M. Cornelissen, R.J.M. Nolte, J.C.M. van Hest, A Three-Enzyme Cascade Reaction through Positional Assembly of Enzymes in a Polymersome Nanoreactor, Chemistry : a European journal, 15, 5, 1107-1114 (2008).
  • H.J. Kitto, E. Schwartz, M. Nijemeisland, M. Koepf, J.J.L.M. Cornelissen, A.E. Rowan and R.J.M. Nolte, Post-modification of helical dipeptido polyisocyanides using the click reaction, J. Mater. Chem., 18, 46, 5615-5624 (2008).
  • V. Palermo, M.B.J. Otten, A. Liscio, E. Schwartz, P.A.J. de Witte, M.A. Castriciano, M.M. Wienk, F. Nolde, G. De Luca, J.J.L.M. Cornelissen, R.A.J. Janssen, K. Muëllen, A.E. Rowan, R.J.M. Nolte, and P. Samori, The Relationship between Nanoscale Architecture and Function in Photovoltaic Multichromophoric Arrays as Visualized by Kelvin Probe Force Microscopy, J. Am. Chem. Soc., 130, 44, 14605-14614 (2008).
  • A.J. Dirks, R.J.M. Nolte, J.J.L.M. Cornelissen, Protein-Polymer Hybrid Amphiphiles, Advanced materials, 20, 20, 3953-3957 (2008).
  • S.S. van Berkel, A.J. Dirks, S.A. Meeuwissen, D.L.L. Pingen, O.C. Boerman, P. Laverman, F.L. van Delft, J.J.L.M. Cornelissen, F.P.J.T. Rutjes, Application of Metal-Free Triazole Formation in the Synthesis of Cyclic RGD-DTPA Conjugates, Chembiochem, 9, 11, 1805-1815 (2008).
  • A. de la Escosura, M. Verwegen, F.D. Sikkema, M. Comellas-Aragonès, A. Kirilyuk, T. Rasing, R.J.M. Nolte and J.J.L.M. Cornelissen, Viral capsids as templates for the production of monodisperse Prussian blue nanoparticles, Chem. Commun., 13, 1542-1544 (2008).
  • Nallani, M.; de Hoog, H.-P. M.; Cornelissen, J. J. L. M.; Palmans, A. R. A.; van Hest, J. C. M.; Nolte, R. J. M., Polymersome Nanoreactors for Enzymatic Ring-Opening Polymerization, Biomacromol, 8, 12, 3723-3728 (2007).
  • A.J. Dirks, J.J.L.M. Cornelissen, F.L. van Delft, J.C.M. van Hest, R.J.M. Nolte, A.E. Rowan, F.P.J.T. Rutjes, From (bio)Molecules to Biohybrid Materials with the Click Chemistry Approach, QSAR & Combinatorial Science, 26, 11-12, 1200-1210 (2007).
  • Marta Comellas-Aragonès, Hans Engelkamp, Victor I. Claessen, Nico A. J. M. Sommerdijk, Alan E. Rowan, Peter C. M. Christianen, Jan C. Maan, Benedictus J. M. Verduin, Jeroen J. L. M. Cornelissen & Roeland J. M. Nolte, A virus-based single-enzyme nanoreactor, Nature Nanotechnology, 2, 10, 635-639 (2007).
  • S. S. van Berkel, A. J. Dirks, M. F. Debets, F. L. van Delft, J. J. L. M. Cornelissen, R. J. M. Nolte, F. P. J. T. Rutjes, Metal-free triazole formation as a tool for bioconjugation., ChemBioChem, 8, 13, 1504-1508 (2007).
  • Gerald A. Metselaar, Dr. 1, Erik Schwartz 1, René de Gelder, Dr. 1, Martin C. Feiters, Dr. 1 *, Serge Nikitenko 2, Grigory Smolentsev, Dr. 3, Galina E. Yalovega, Dr. 3, Alexander V. Soldatov, Prof. Dr. 3, Jeroen J. L. M. Cornelissen, Dr. 1, Alan E. Rowan,, X-Ray Spectroscopic and Diffraction Study of the Structure of the Active Species in the NiII-Catalyzed Polymerization of Isocyanides, ChemPhysChem, 8, 12, 1850-1856 (2007).
  • F.D. Sikkema, M. Comellas-Aragones, R.G. Fokkink, B.J.M Verduin, J.J.L.M. Cornelissen, R.J.M. Nolte, Monodisperse Polymer-Virus Biohybrid Nanoparticles, Org. Biom. Chem., 5, 54-57 (2007).
  • E. Schwartz, H.J. Kitto, R. de Gelder, R.J.M. Nolte, A.E. Rowan and J.J.L.M. Cornelissen, Synthesis, characterisation and chiroptical properties of clickable polyisocyanopeptides, J. Mater. Chem., 17, 19, 1876-1884 (2007).
  • G.A. Metselaar, S.J. Wezenberg, J.J.L.M. Cornelissen, R.J.M. Nolte, A.E. Rowan, Lyotropic Liquid Crystalline Behavior of Polyisocyanodipeptides, J. Pol. Sci., Part A: Polym. Chem., 45, 981-988 (2007).
  • I.C. Reynhout, J.J.L.M. Cornelissen and R.J.M. Nolte, Self-assembled Architectures from Biohybrid Triblock Copolymers, J. Am. Chem. Soc., 129, 8, 2327-2332 (2007).
  • G.A. Metselaar, P.J.H.M. Adams, R.J.M. Nolte, J.J.L.M. Cornelissen and A.E. Rowan, Polyisocyanides Derived from Tripeptides of Alanine, Chemistry - A European Journal, 13, 3, 950-960 (2007).
  • van Hest, J.C.M.; Vriezema, D.M.; Garcia, P.M.L.; Cornelissen, J.J.L.M.; Rowan, A.E., & Nolte, R.J.M.;, Enzyme positional assembly in polymeric capsules., Polym. Prepr., 47, 238 (2006).
  • Lambermon, M.H.L; Hendriks, L.J.A.; Schoffelen, S.; Vos, M.R.J.; Hatzakis, N.S.; Carette, N.; Rowan, A.E.; Cornelissen, J.J.L.M.; Michon, T.; Sommerdijk, N.A.J.M., & van Hest, J.C.M.;, Assembly Strategies for Enzyme Immobilization., Polymer Preprints, 47, 209-210 (2006).
  • S.J. Wezenberg, G.A. Metselaar, A.E. Rowan, J.J.L.M. Cornelissen, D. Seebach and R.J.M. Nolte, Synthesis, characterization and folding behavior of ?-amino acid derived polyisocyanides, Chem. Eur. J., 12, 10, 2778-2786 (2006).
  • M.B.J. Otten, E. Schwartz, P.A.J. de Witte, J.J.L.M. Cornelissen, M.M. Wienk, R.A.J. Janssen, R.J.M. Nolte, A.E. Rowan, Helical Perylene Polymers for Application in Photovoltaic Devices, PMSE, 94, 743 (2006).
  • J.J.L.M. Cornelissen, A.J. Dirks, I.C. Reynhout, R.J.M. Nolte, Self-Organization of Polymer-Protein Hybrid Amphiphiles, PMSE, 94, 87 (2006).
  • I.C. Reynhout, J.J.L.M. Cornelissen, R.J.M. Nolte, Complex Nanostructures from Biohybrid Block Copolymers, PMSE, 94, 155 (2006).
  • A.J. Dirks, N.S. Hatzakis, J.J.L.M. Cornelissen, R.J.M. Nolte, Functional Biohybrid Amphiphiles, PMSE, 94, 369 (2006).
  • A. (Ton) J. Dirks, Sander S. van Berkel, Nikos S. Hatzakis, Joost A. Opsteen, Floris L. van Delft, Jeroen J. L. M. Cornelissen, Alan E. Rowan, Jan C. M. van Hest, Floris P. J. T. Rutjes and Roeland J. M. Nolte, Preparation of Biohybrid Amphiphiles via the Copper Catalysed Huisgen [3 + 2] Dipolar Cycloaddition Reaction, Chemical Communications, 33, 4172-4174 (2005).
  • A. Kros, W. Jesse, G.A. Metselaar, J.J.L.M. Cornelissen, Rod-rod Diblock Copolymer Formation by Change-of-Mechanism Ni Catalyzed Polymerization of N-carboxy anhydrides and Isocyanides, Angew. Chem. Int. Ed. Eng., 44, 28, 4349-4352 (2005).
  • D.M. Vriezema, M. Comellas Aragonés, J.A.A.W. Elemans, J.J.L.M. Cornelissen, A.E. Rowan, R.J.M. Nolte, Self-Assembled Nanoreactors, Chemical Reviews, 36, 32, 1445-1489 (2005).
  • G.A. Metselaar, J.J.L.M. Cornelissen, A.E. Rowan, R.J.M. Nolte, Acid- initiated stereospecific polymerization of isocyanopeptides, Angewandte Chemie International Edition, 117, 13, 2026-2029 (2005).
  • G. Mantovani, F. Lecolley, L. Tao, D.M. Haddleton, J. Clerx, J.J.L.M. Cornelissen, K. Velonia, Design and synthesis of new N-maleimido-functionalized hydrophilic polymers via copper-mediated living radical polymerization: a suitable alternative to PEGylation chemistry, J. Am. Chem. Soc., 127, 9, 2966-2973 (2005).
  • G.A. Metselaar, J.J.L.M. Cornelissen, A.E. Rowan, Prof., R.J.M. Nolte, Acid-Initiated Stereospecific Polymerization of Isocyanopeptides, Angewandte Chemie (International ed.), 44, 13, 1990-1993 (2005).
  • I.C. Reynhout, D.W.P.M. Löwik, J.C.M. van Hest, J.J.L.M. Cornelissen, R.J.M. Nolte, Solid phase synthesis of Biohybrid Block Copolymers, Chem. Commun., 5, 602-604 (2005).
  • F. de Loos, I.C. Reynhout, J.J.L.M. Cornelissen, A.E. Rowan, R.J.M. Nolte, Construction of Functional Porphyrin-Polystyrene nano-architectures by ATRP, Chemical Communications, 1, 60-62 (2005).
  • J.J.L.M. Cornelissen, A.J. Dirks, J.A. Opsteen, I.C. Reynhout, N. Hatzakis, J. Sly, A.E. Rowan, J.C.M. van Hest, R.J.M. Nolte, Functional Nano-Sized Assemblies from Amphiphilic Biohybrid Macromolecules, Polymer Preprints, 46, 41 (2005).
  • J.J.L.M. Cornelissen, M. Fischer, R. van Waes, R. van Heerbeek, P.C.J. Kamer, J.N.H. Reek, N.A.J.M. Sommerdijk, R.J.M. Nolte, Synthesis, Characterization and Aggregation Behavior of Block Copolymers containing a Polyisocyanopeptide Segment, Polymer, 45, 22, 7417-7430 (2004).
  • D.M. Vriezema, A. Kros, R. de Gelder, J.J.L.M. Cornelissen, A.E. Rowan and R.J.M. Nolte, Electroformed giant vesicles from thiophene containing rod-coil diblock copolymers, Macromolecules, 37, 12, 4736-4739 (2004).
  • J.J.L.M. Cornelissen, W.S. Graswinckel, A.E. Rowan, N.A.J.M. Sommerdijk, R.J.M. Nolte, Conformational analysis of dipeptide-derived polyisocyanides, Journal of polymer science. Part A, Polymer chemistry, 41, 11, 1725-1736 (2003).
  • P.A.J. de Witte, M. Castriciano, J.J.L.M. Cornelissen, L. Monsù Scolaro, R.J.M. Nolte, A.E. Rowan, Helical Polymer-Anchored Porphyrin Nanorods, Chemistry : a European journal, 9, 8, 1775-1781 (2003).
  • J.J.L.M. Cornelissen, N.A.J.M. Sommerdijk, R.J.M. Nolte, Determination of the helical sense in alanine based polyisocyanides, Macromolecular Chemistry and Physics, 203, 10-11, 1625-1630 (2002).
  • P. Samorí, C. Ecker, I. Gössl, P.A.J. de Witte, J.J.L.M. Cornelissen, G.A. Metselaar, M.B.J. Otten, A.E. Rowan, R.J.M. Nolte and J.P. Rabe, High Shape Persistence in Single Polymer Chains Rigidified with Lateral Hydrogen Bonded Networks, Macromolecules, 35, 13, 5290-5294 (2002).
  • J.J.L.M. Cornelissen, R. van Heerbeek, P.C.J. Kamer, J.N.H. Reek, N.A.J.M. Sommerdijk, R.J.M. Nolte, Silver Nanoarrays Templated by Block Copolymers of Carbosilane Dendrimers and Polyisocyanopeptides, Advanced Materials, 14, 7, 489-492 (2002).
  • J.J.L.M. Cornelissen, W.S. Graswinckel, P.J.H.M. Adams, G.H. Nachtegaal, A.P.M. Kentgens, N.A.J.M. Sommerdijk, R.J.M. Nolte, Synthesis and characterization of polyisocyanides derived from alanine and glycine dipeptides, Journal of polymer science. Part A, Polymer chemistry, 39, 24, 4255-4264 (2001).
  • J.J.L.M. Cornelissen, J.J.J.M. Donners, R. de Gelder, W.S. Graswinckel, A.E. Rowan, N.A.J.M. Sommerdijk, and R.J.M. Nolte, Beta-Helical polymers from isocyanopeptides, Science, 293, 5530, 676-680 (2001).
  • J.J.L.M. Cornelissen, M. Fischer, N.A.J.M. Sommerdijk, R.J.M. Nolte, Helical superstructures from charged poly(styrene)-poly(isocyanodipeptide) block copolymers, Science, 280, 5368, 1427-1430 (1998).
  • Clerx, J.; Spiering, M.M.; Zhuang, Z.; Benkovic, S.J.; Cornelissen, J.J.L.M.; Rowan, A.E., & Nolte, R.J.M.;, Artificial Processive Enymes based on the T4 Replisome., Polymer Preprints, 47, , 207- (2006).
  • K. Velonia, J.J.L.M. Cornelissen, M.C. Feiters, A.E. Rowan and R.J.M. Nolte, Chapter 7: Aggregation of Amphiphiles as a Tool to Create Novel Functional NanoObjects, Nanostructure Science and Technology, Series Ed.: Lockwood, David J., 119, (2005).
  • J.A. Opsteen, J.J.L.M. Cornelissen, J.C.M. van Hest, Block Copolymer Vesicles, Pure Appl. Chem., 76, 7-8, 1309-1319 (2004).
  • G.A. Metselaar,; R. de Gelder,; M.C. Feiters,; S. Nikitenko,; G.Y. Smolentsev,; G.E. Yalovega,; A.V. Soldatov,; J.J.L.M. Cornelissen,; A.E. Rowan,; R.J.M. Nolte.;, X-ray Spectroscopic and Diffraction Study of the Structure of the Active Species in the Ni(II) Catalyzed Polymerization of Isocyanides., ChemPhysChem, 8, 1850-1856 (2007).
  • G.A. Metselaar,; Matthijs B.J. Otten,; J.J.L.M. Cornelissen,; A.E. Rowan. R.J.M. Nolte,, Polyisocyanides: stiffed foldamers," Foldamers. Structure, properties and applications., Huc S. Hecht vol. Wiley-VCH Verlag GmbH & Co., Weinheim., 367-402 (2007).
  • H.-P.M. de Hoog, D.M. Vriezema, M. Nallani, S. Kuiper, J.J.L.M. Cornelissen, A.E. Rowan and R.J.M. Nolte, Tuning the properties of PS-PIAT block copolymers and their assembly into polymersomes, Soft matter, 4, 5, 1003-1010 (2008).
  • S.F.M. van Dongen, M. Nallani, S. Schoffelen, J.J.L.M. Cornelissen, R.J.M. Nolte, J.C.M. van Hest, A Block Copolymer for Functionalisation of Polymersome Surfaces, Macromolecular rapid communications, 29, 4, 321-325 (2008).
  • Kitto, Heather J.; Schwartz, Erik; Nijemeisland, Marlies; Koepf, Matthieu; Cornelissen, Jeroen J. L. M.; Rowan, Alan E.; Nolte, Roeland J. M., Post-modification of helical dipeptido polyisocyanides using the 'click' reaction., Journal of Materials Chemistry, 18, 46, 5615-5624 (2008).
  • Kuiper, Suzanne M.; Nallani, Madhavan; Vriezema, Dennis M.; Cornelissen, Jeroen J. L. M.; van Hest, Jan C. M.; Nolte, Roeland J. M.; Rowan, Alan E., Enzymes containing porous polymersomes as nano reaction vessels for cascade reactions., Organic & Biomolecular Chemistry, 6, 23, 4315-4318 (2008).
  • Palermo, Vincenzo; Otten, Matthijs B. J.; Liscio, Andrea; Schwartz, Erik; de Witte, Pieter A. J.; Castriciano, Maria Angela; Wienk, Martijn M.; Nolde, Fabian; De Luca, Giovanna; Cornelissen, Jeroen J. L. M.; Janssen, Rene A. J.; Mullen, Klaus; Rowan, Alan, The Relationship between Nanoscale Architecture and Function in Photovoltaic Multichromophoric Arrays as Visualized by Kelvin Probe Force Microscopy., Journal of the American Chemical Society, 130, 44, 14605-14614 (2008).
  • Elemans, Johannes A. A. W.; Cornelissen, Jeroen J. L. M.; Feiters, Martinus C.; Rowan, Alan E.; Nolte, Roeland J. M., Bio-inspired supramolecular catalysis., Supramolecular Catalysis, 143-164 (2008).
  • Kentgens, Arno P. M.; van Eck, Ernst R. H.; Gowda, Chandrakala; Nolte, Roeland J. M.; Cornelissen, Jeroen J. L. M.; Rowan, Alan E., Magic angle spinning and micro-MAS NMR spectroscopy of biomimetic polymers., Polymer Preprints, 49, 1, 693-694 (2008).
  • Lim, Eunhee; Tu, Guoli; Schwartz, Erik; Cornelissen, Jeroen J. L. M.; Rowan, Alan E.; Nolte, Roeland J. M.; Huck, Wilhelm T. S., Synthesis and Characterization of Surface-Initiated Helical Polyisocyanopeptide Brushes., Macromolecules, 41, 6, 1945-1951 (2008).