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Dr. Kerensa Broersen

BASIC INFO

Name Kerensa Broersen
E-mail k.broersen@utwente.nl
Room Zuidhorst 111
Phone +31 53 489 3655
Function Associate Professor
 

MORE INFO

Kerensa Broersen is an associate professor in the Applied Stem Cell Technologies group since 2019. She supervises a team of researchers interested in the biochemical and cell biological aspects of the brain as a function of aging. She was trained as a biochemist and obtained her PhD in food chemistry from Wageningen University in The Netherlands. After this she moved to the Medical Research Council - Laboratory of Molecular Biology to work for two years as a postdoc with Bazbek Davletov and Michel Goedert on the aggregation of alpha-synuclein, a protein involved in Parkinson's disease, as a function of a number of membrane-enriched fatty acids. She then worked for three and a half years, first as a postdoc, later as an assistant professor, in the Switch Laboratory, headed by Frederic Rousseau and Joost Schymkowitz, at the Free University of Brussels (VUB) and Flanders Institute for Biotechnology (VIB). Here, she worked on amyloid beta, a hallmark peptide that forms deposits in the brains of Alzheimer’s disease patients. She demonstrated that various amyloid beta peptide isoforms that exist strongly affect each other and can predict outcome of pathology progress. Since 2011 Broersen worked at the University of Twente in the Nanobiophysics Group at the Science and Technology faculty, first as assistant professor and since 2016 as associate professor. In 2018 she joined the laboratory of Randy Schekman at the University of California – Berkeley, for a sabbatical. Here she investigated the non-conventional secretion of the protein tau from neuroblastoma cells and brain organoids. In 2019 Broersen transferred to the Applied Stem Cell Technologies group at the University of Twente and Technical Medical Centre.   

Projects

A gut-brain-on-a-chip platform – understanding bidirectional interaction between the microbiome and the brain
Funded by NWO - Zwaartekracht
                PhD student                      : Lena Koch
                Saxion students                : Said Abdullah
                                                            Brian Teeuw

Non-conventional secretion of tau from neuronal cells 
Funded by Alzheimer Nederland, Fulbright

Exploring the potential of multi-target treatment for Alzheimer’s disease
Funded by ZonMw - Memorabel
                PhD student                      : Federica Cioffi (NBP)

Protein DOMINO: Amyloid exposure and associated risks
Funded by STW
                PhD student                      : Jonathan Vaneyck (NBP)