See Assignments 2011-2012

Vascular complications in percutaneous procedures

Voorstel MDO-opdracht

Opleiding Technische Geneeskunde

Universiteit Twente

A. Algemeen

1. Titel MDO-opdracht: Vascular complications in percutaneous procedures

2. Gegevens instelling/indiener:

Naam indiener: Henk Marquering

Instelling/afdeling: Radiologie/Biomedical Engineering & Physics en Vasculaire Chirurgie


Medisch begeleider: Dr Mark Koelemaij

Technologisch begeleider (UT): F. van der Heijden (EWI/S&S)

B. Faciliteiten

1. Welke faciliteiten zijn nodig voor een adequate uitvoering van de vraagstelling?


2. Wat zijn daarbij mogelijke risico’s voor de voortgang van de opdracht?


C. Overige opmerkingen


D. Inhoudelijke informatie MDO-opdracht

1. Omschrijving van de technisch geneeskundige vraagstelling (maximaal 400 woorden)

N.B.: zo mogelijk directe afstemming tussen medische en technische groep, anders hiervoor contact opnemen met de opleiding TG.


Minimally invasive surgery is increasingly applied because of the proven better outcome and benefits for the patient such as less pain, shorter hospital stay, and less injury.

Examples of such minimally invasive procedure include Endovascular Aortic Repair (EVAR), endovascular coiling of intracranial aneurysms, and Transcatheter Aortic Valve Implantation (TAVI).

These procedures have in common that a device is transported through the iliac and aortic artery after an incision in the groin to the problematic location in the body. Unfortunately, these percutaneous procedures are associated with vascular complications of the iliac artery. These vascular complications include bleeding, vascular rupture, aneurysm spurium, ateriorvenous fistula, dissection, and embolism. There are various clinical and technical procedural parameters associated with these vascular complications. Next to these parameters, the morphology and disease of the vasculature also influence the risk of vascular complications, for example stenosed and calcified arteries.


The goal of this project is to determine the patient-specific risk factors of vascular complications, and to describe how these can be imaged and quantified. These factors should be combined in a general (non-procedural specific) risk model. As a result such a model could be used to support clinical treatment decision making in the consideration of open- or minimally invasive surgery.


Datum: 14-12-2012

Naam indiener: Henk Marquering

Handtekening indiener:

Gaarne dit formulier retourneren aan:

Universiteit Twente

Opleiding Technische Geneeskunde

Gebouw Noordhorst

Postbus 217

7500 AE Enschede