The Lab for Professional Learning in High-Tech Health Care specializes in research on expertise and professional development of high-tech health care professionals. Researchers in our network study professional development as well as knowledge and skill acquisition within the broad domain of health professions education. The scope of the research ranges from professional identity development of undergraduate technical medical students to workplace-based assessment of experienced surgeons. The research program is closely aligned with educational development within the high-tech health care curricula of the University of Twente. National and international collaborations strengthen our approach and our results are disseminated through journal publications, conference presentations and workshops among others.