EndNote is a software tool for managing your own personal library. You can save full-text articles in your own database and use that to build reference lists in your own work.
References can be imported via the import citation options many research databases offer. Full text can be save instantly. The large output style library allows you to use EndNote for in article citations and the reference list for almost all publishing styles and requested formats.
The University of Twente has a license for EndNote that also allows for it to be installed at home, and with the new 7.0 features the synchronization of your EndNote library over different computers has become a stable feature.