Hand assessment with the PowerGlove: towards application in Parkinson’s disease patients during Deep Brain Stimulation implantation
Background and problem statement
Parkinson’s disease is a movement disorder characterized by tremor, muscle rigidity and a slowing and loss of physical movement. A novel treatment of Parkinson’s disease is deep brain stimulation (DBS). An electrode placed in the brain electrically stimulates a small area of the brain continuously. Assessment of the hand is very important prior, during and after DBS implantation surgery. It is clinically scored using e.g. the Unified Parkinson's Disease Rating Scale (UPDRS).
Recently, in the PowerSensor project new sensors (inertial and magnetic) have been developed that are applied in a PowerGlove to measure movement of the hand and fingers, and the interaction between the hand and environment in terms of forces and moments.
Application of this PowerGlove during DBS implantation surgery will enable more accurate measure of hand function and quantification of the Parkinson’s disease motor symptoms. Therefore, important outcome parameters that are related to the UPDRS need to be defined.
The objective of this study is to develop and test a measurement protocol for hand assessment using the PowerGlove, that can be applied in Parkinson patients during DBS implantation, to quantify Parkinson’s disease motor symptoms.
- Selection of movement tasks that are relevant for hand assessment in Parkinson, based on e.g. the UPDRS
- Experiments in healthy subjects with the PowerGlove aiming to evaluate the defined tasks in terms of feasibility, reliability, accuracy and outcome parameters
•Experiments in healthy subjects
•Data Analysis of the PowerGlove
Principal Investigator track
Central motor control
Supervision and info