Andrea Manca is Professor of Health Economics in the Centre for Health Economics at the University of York (UK), and co-editor of the scientific journals Value in Health and a PLOS ONE. His research interests focus on developing methodological solutions to address the issues faced by healthcare decision makers when trying to analyse and interpret health economics and outcomes research data. In many cases these require the use of advanced statistical and decision modelling methods for the analysis of cost effectiveness data, combining quantitative evidence synthesis and health econometrics, and personalised medicine is one example of research and policy areas that require complex health economics modelling. Andrea has more than 15 years of experience in his field of research and has evaluated health technologies in several clinical areas including breast and advanced colorectal cancer, endovascular aneurysm repair, coronary revascularisation, diabetes, neck and chronic low back pain, surgical interventions for urinary stress incontinence, and hysterectomy. He has published more than 60 peer reviewed scientific papers in applied and methodological journals. In 2007 he completed a post‑doctoral Research and Training Fellowship in Health Services Research awarded by The Wellcome Trust. His work on the analysis of multinational cost-effectiveness data received the ISPOR 2008 Research Excellence Award for Methodology. In 2009 Andrea was awarded a prestigious Career Development Fellowship funded by the National Institute for Health Research (NIHR) titled “Developing economic evaluation methods for decision making: the value of access to individual patient data”. Andrea is currently member of the NICE Technology Appraisal Committee, and Deputy Chair of the UK National Institute of Health Research (NIHR) Doctoral Research Fellowships panel.