Staff

s.siesling

Full Professor (part-time)

 

 

 

Address

Sabine Siesling

 

MB-HTSR

 

PO Box 217

 

7500 AE Enschede

 

 

E-mail

s.siesling@utwente.nl

Telephone

(053) 489 5374

Fax

(053) 489 2159

 

Background

Sabine Siesling was born on the 29th of July 1972 in Hengelo (O) the Netherlands. She is involved in several (inter-) national studies (i.e. National Cancer Control Plan, trends in cancer in the Netherlands, EUROCARE, RARECARE, EUROCHIP, EUROCOURSE). Her main interests is the role of interventions (reaching from care pathways to technological innovations) in quality and cost-effectiveness of oncological care (i.a. in breast, lung, colorectal and rare cancers). She is involved in the project concerning the individualization of follow-up programs for cancer patients. Also the specific role of imaging techniques in oncological care in relation to geographical differences in incidence and outcome (i.e. cervical cancer, mesothelioma, melanoma) is topic of interest.

Curriculum Vitae

Present position:

Jan’11-now Comprehensive Cancer Centre The Netherlands, location Groningen/Enschede, head of the department of Research

Jun’08-dec’10 Comprehensive Cancer Centre North East, head of the department of Research

Sept’99-Jun’08 Comprehensive Cancer Centre Stedendriehoek Twente, head of the department of Research and Registration

Jan’08-now University Twente, researcher department Health Technology and Services Research (HTSR)

Education:

Febr’96 -Aug’99 PhD: “Clinical, genetical and epidemiological aspects of Huntington Disease” department of Neurology, Leiden University Hospital, Leiden, the Netherlands, promoter Prof. R.A.C. Roos. Registration as Epidemiologist

Sep’90 - Febr’96 Biomedical Sciences, Leiden University, the Netherlands

Internships (as part of the study Biomedical Sciences):

Feb’95 - Jan’96 “Assessment of movement in Hun­tington’s Disease, a one year follow-up”

department of Neurology, Prof R.A.C.Roos, Leiden University, the Netherlands

factor analysis; clinical-trial “Clozapin, a possible treatment in Hun­tington’s Disease?”

Sep’94 - Dec’94 “Serum level of superoxid dismutase as a pro­gnostic factor in malignant ischemic stroke”

department of Neurology, Prof.W.Hacke, Kopfklinik Univer­si­tät Heidelberg, Germany

Mrt’94 - Jul’94 “The effect of intracellular glutathione on the production of cytokines”

department of Rheumatology, Leiden University Hospital, Leiden, the Netherlands

Nov’93 - Apr’94 “Clinical use of otoacoustic emissions in children from 4 to 8 years”

department Ear, Nose and Throat, Leiden University Hospital, Leiden, the Netherlands

Memberships:

Nov’92-Nov’93 board of the Medical Faculty Leiden University

Jan’02-now chair of the Working Group of the Netherlands Cancer Registry

Nov’03-Nov’04 member of the “cancer care” working group of the National Cancer Control Plan

Oct’04-Apr’06 supervisor of the “Health indicators” working group of the Nat. Cancer Control Plan

Jan ‘07-now supervisor of the “Monitor Working group” of the Nat.Cancer Control Plan

2006-now member of the EUROCARE-3 projectgroup: Incidence, survival and mortality of cancer in Europe

2007-now member of the RARECARE projectgroup: Indicators of Health Care, incidence, survival and prevalence of rare cancers in Europe (Workpackage 5)

member of the Dutch Society of Epidemiologists

member of the Society for Public Health and Research

member of the European Network of Cancer Registries (ENCR)

member of the International Agency of Cancer Registries (IACR)

member of the Committee of Technical Medical Science, University Twente, Enschede

member of the Epidemiological Society Twente

member of the Working community Netherlands Society for Cancer Relief/Queen Wihelmina Foundation

member of the scientific Committee UKACR&NCR meeting oct 2006

Publications

Publication<list

Hanneke AHJ Klopper-Kes, Sabine Siesling, Nienke Meerdink, Celeste PM Wilderom, Wim H van Harten, Quantifying culture gaps between physicians and managers in Dutch hospitals: a survey, BMC Health Services Research 2010, 10:86 Article URL http://www.biomedcentral.com/1472-6963/10/86

Jan J. Jobsen, Lambert Naudin ten Cate, Marnix L.M. Lybeert, Elzbieta M. van der Steen-Banasik, Astrid Scholten, Job van der Palen, Annerie Slot, Marika C. Stenfert Kroese, Eltjo M.J. Schutter, Sabine Siesling, The number of metastatic sites for stage IIIA endometrial carcinoma, endometrioid cell type, is a strong negative prognostic factor, Gynecologic Oncology 117 (2010) 32–36

M. A. G. Elferink, S. Siesling, O. Visser, H. J. Rutten, J. H. J. M. van Krieken, R. A. E. M. Tollenaar & V. E. P. P. Lemmens Large variation between hospitals and pathology laboratories in lymph node evaluation in colon cancer and its impact on survival, a nationwide populationbased study in The Netherlands, Annals of Oncology Advance Acces published July 1, 2010

M.A.G. Elferink,P. Krijnen, M.W.J.M. Wouters, V.E.P.P. Lemmens, M.L.E.A. Jansen-Landheer, C.J.H. van de Velde, J.A. Langendijk, C.A.M. Marijnen, S. Siesling, R.A.E.M. Tollenaar, Variation in treatment and outcome of patients with rectal cancer by region, hospital type and volume in the Netherlands, EJSO xx (2010) 1-9

M.A.G. Elferink, M.W.J.M. Wouters, P. Krijnen, V.E.P.P. Lemmens, M.L.E.A. Jansen-Landheer, C.J.H. van de Velde, S. Siesling, R.A.E.M. Tollenaar Disparities in quality of care for colon cancer between hospitals in the Netherlands, EJSO xx (2010) 1-10

M.W.J.M. Wouters, S. Siesling, M.L. Jansen-Landheer, M.A.G. Elferink,

J. Belderbos, J.W. Coebergh, F.M.N.H. Schramel, Variation in treatment and outcome in patients with non-small cell lung cancer by region, hospital type and volume in the Netherlands, EJSO xx (2010) 1-10

de Kok IM, van der Aa MA, van Ballegooijen M, Siesling S, Karim-Kos HE, van Kemenade FJ, Coebergh JW; Trends in cervical cancer in the Netherlands until 2007: Has the bottom been reached? On behalf of the Working Group Output of the Netherlands Cancer Registry. Int J Cancer. 2010 Jul 12. [Epub ahead of print]

van Steenbergen LN, Elferink MA, Krijnen P, Lemmens VE, Siesling S, Rutten HJ, Richel DJ, Karim-Kos HE, Coebergh JW; Improved survival of colon cancer due to improved treatment and detection: a nationwide population-based study in The Netherlands 1989-2006. on behalf of the Working Group Output of The Netherlands Cancer Registry. Ann Oncol. 2010 May 3. [Epub ahead of print]

Elferink MA, van Steenbergen LN, Krijnen P, Lemmens VE, Rutten HJ, Marijnen CA, Nagtegaal ID, Karim-Kos HE, de Vries E, Siesling S; Marked improvements in survival of patients with rectal cancer in the Netherlands following changes in therapy, 1989-2006. Working Group Output of the Netherlands Cancer Registry.

Eur J Cancer. 2010 May;46(8):1421-9. Epub 2010 Feb 19.

Driece HA, Siesling S, Swuste PH, Burdorf A., Assessment of cancer risks due to environmental exposure to asbestos, J Expo Sci Environ Epidemiol. 2010 Jul;20(5):478-85. Epub 2009 Oct 28.PMID: 19865072 [PubMed - in process]Related citations

Van der Aa, I.de Kok, S.Siesling. M van Ballegooijen, JW Coebergh. “Geen basis voor verlaging

onderste leeftijdsgrens van bevolkingsonderzoek op baarmoederhalskanker” NtvG 2009; 16: 754-758

Driece HA, Siesling S, Swuste PH, Burdorf A. "Assessment of cancer risks due to environmental

exposure to asbestos." J Expo Sci Environ Epidemiol. 2009 Oct 28. [Epub ahead of print]

van der Aa MA, Siesling S, v d Poll-Franse LV, Schutter EM, Lybeert ML, Coebergh JW.

“Age-specific differences in the treatment of cervical cancer in the east and the south of The Netherlands 1989-2004.”Eur J Obstet Gynecol Reprod Biol. 2009 Nov;147(1):78-82. Epub 2009 Aug 26.

Schaapveld M, Visser O, Siesling S, Schaar CG, Zweegman S, Vellenga E. “Improved survival among younger but not among older patients with Multiple Myeloma in the Netherlands, a population-based study since 1989.” Eur J Cancer. 2009 Aug 12. [Epub ahead of print]

van Uden-Kraan CF, Drossaert CH, Taal E, Smit WM, Moens HJ, Siesling S, Seydel ER, van de Laar

MA.”Health-related Internet use by patients with somatic diseases: frequency of use and characteristics of users.” Inform Health Soc Care. 2009 Jan;34(1):18-29.

van der Aa MA, Siesling S, Kruitwagen RF, Lybeert ML, Coebergh JW, Janssen-Heijnen ML. “Comorbidity and age affect treatment policy for cervical cancer: a population-based study in the south of The Netherlands, 1995-2004.” Eur J Gynaecol Oncol. 2008;29(5):493-8.


S Siesling, LV van de Poll-Franse, JJ Jobsen, OJ Repelaer van Driel, AC Voogd. “Trends en variaties in mammasparende operaties in Zuidoost-en Oost-Nederland in de periode 1990-2002” Ned Tijdschr Geneeskd 2005;149:1941-6

M van der Heijden-van der Loo, PD Bezemer, A Hennipman, S Siesling, PJ van Diest, V Bongers, PHM Peeters. “ Introduction of sentinel node biopsy and stage migration of breast cancer” EJSO, The Journal of Cancer Surgery, 32 (2006) 710-714; 2006

S Siesling, O Visser, JAAM van Dijck, JWW Coebergh. “Trends in incidentie van en sterfte aan kanker in de periode 1989-2003 in Nederland” Ned Tijdschr Geneeskd 2006;150;2490-6

S Siesling, O Visser, JAAM van Dijck, JWW Coebergh. Rectificatie figuren en tabel “Veranderingen in incidentie van kanker in Nederland in de periode 1989-2003” Ned Tijdschr Oncologie, jaargang 3 nr 6 278; 2006

S Siesling, M Elferink, JAAM van Dijck, JP Pierrie, W Blokx. “Extra-mammaire Paget’s Disease in the Netherlands” Eur J Surg Oncol 2007; 33(8): 951-5.

H Sinninghe Damste, S Siesling, A Burdorf. “Invloed van milieublootstelling aan asbest in de regio Goor op het optreden van het maligne mesothelioom onder vrouwen” Ned Tijdschr Geneeskd 2007;151:2453-9

S Siesling.,LV van de Poll-Franse, JJ Jobsen., OJ Repelaer van Driel., AC Voogd. “Explanatory factors for variation in the use of Breast Conserving Surgery and Radiotherapy in the Netherlands, 1990-2001” The Breast 2007;16;606-614

A Burdorf, B Järvholm, S Siesling ”Asbestos exposure and differences in occurrence of peritoneal mesothelioma in the Netherlands and Sweden” Occup. Environ. Med. 2007; 64;839-842

PH Spruit, S Siesling, MAG Elferink, EJA Vonk and CJM Hoekstra ” Regional radiotherapy versus an axillary lymph node dissection after lumpectomy: a safe alternative for an axillary lymph node dissection in a clinically uninvolved axilla in breast cancer. A case control study with 10 years follow up.” Rad Oncol 2007;2:40

S.Siesling, M. vd Aa, JW Coebergh, E.Pukkala on behalf of the Working Group of the Netherlands Cancer Registry. “Time-space trends in cancer incidence in The Netherlands in 1989-2003” Int J Cancer 2008;122:2106-2114

Van der Aa MA, Schutter EM, Looijen-Salamon M, Martens JE, Siesling S. “Differences in screening history, tumour characteristics and survival between women with screen-detected versus not screen-detected cervical cancer in the east of the Netherlands” Eur J Obstetrics & Gynaecology and Respoductive Biology, on line 2007

Jobsen JJ, Lybeert ML, van der Steen-Banasik EM, Slot A, van der Palen J, Naudin ten Cate LN, Scholten A, Coen V, Schutter EM, Siesling S “Multicentre study on outcome and risk factors in endometrial carcinoma pathological stage II” Int Journal Gynaecology, on line 2007

Van der Aa MA, Siesling S, Louwman, Pukkala, Coebergh ” Geographical relationships between health related factors and incidence of cervical cancer” Eur J Cancer Prevention, accepted 2007

Van der Aa MA, Pukkala E, Coebergh JW, Antilla A, Siesling S “Mass screening programmes and trends in cervical cancer in Finland and the Netherlands” Int J Cancer 2008;122:1854-1858

Van der Aa, Siesling, Kruitwagen, Lybeert, Coebergh, Janssen-Heijnen “Co-morbidity and age affect treatment policy for cervical cancer: a population based study in the south of the Netherlands, 1995-2004” accepted Eur J Gyn Oncology 2007

Karim-Kos HE, de Vries E, Soerjomataram I, Lemmens V, Siesling S, Coebergh JWW. “Recent trends of cancer in Europe: A combned approach of incidence, survival and mortality for 17 cancer sites since the 1990s” in press Eur J Cancer 2008