Staff

Sofie Berghuis

PhD Student

Address MB-HTSR
PO Box 217
7500 AE Enschede

E-mail: a.m.berghuis@utwente.nl

Phone: (053) 489 5189

Background

Sofie Berghuis finished her bachelor in Health Sciences in 2014 at the University of Twente. In 2015 she completed the master Health Sciences with the track Health Technology Assessment and Innovation. Her final research project was on the health economic impact of circulating tumor cells in early stage breast cancer. After graduation Sofie started working as a junior researcher at the department of Health Technology and Services research. In March 2016 she started her PhD on blood based biomarkers in breast cancer.

Research

The main subject of Sofie her research project is blood based biomarkers in breast cancer. Breast cancer is the most frequently diagnosed form of cancer among women. Although progress in diagnostics and treatment advances have been made, the metastatic disease still largely is an incurable condition. To reduce the development of distant metastases, and to treat these best, it is important to detect the metastases and start personalized treatment as early as possible. Currently that is done by using several imaging techniques or combinations of those. Unfortunately these imaging techniques are not able to detect micro metastases or characterize these micro metastases. A possible solution for enabling earlier detection and characterization of possible metastases is the use of liquid biopsies, to detect, for example free circulating DNA, microRNA or circulating tumor cells. The aim of this project is to summarize the state of technology of all currently existing blood based biomarkers and to value these based on their probable impact for future health care.

Education

2015

Master of Science in Health Sciences, University of Twente

2014

Bachelor of Science in Health Sciences, University of Twente

Work Experience

March 2016 – present
PhD Student at the department of Health Technology and Services Research

October 2015 – December 2015
Junior researcher at the department of Health Technology and Services Research

Conference presentations

Berghuis AMS, Koffijberg H, Terstappen LWMM, Rack B, Neubauer H, Fehm T and IJzerman MJ: Using CTC detection to guide systemic treatment in stage IA breast cancer. Proc. SMDM, June 12-14, London, UK.

Berghuis AMS, Koffijberg H, Terstappen LWMM, RACK B, Neubauer H, Fehm T and Ijzerman MJ: What do you believe? An online tool for cost-effectiveness analysis of circulating tumor cell detection based on user beliefs. Proc. SMDM, October 23-26, Vancouver, Canada

CTC Cost-Effectiveness Tool